Von Willebrand factor and ADAMTS13 activity as clinical severity markers in patients with COVID-19COVID-19 환자의 임상 중증도 마커로서의 폰 빌레브란트 인자 및 ADAMTS13 활성Article Published on 2021-08-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, SARS, 바이오마커, [키워드] ADAMTS13 age and gender Antigen clinical outcomes Clinical severity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outpatient COVID-19 outpatients COVID-19 patient COVID-19 patients D-dimer diagnosed disease severity Endothelial dysfunction endothelial injury enrolled evaluate fibrinogen healthy individual highest hypercoagulability ICU patient ICU Patients Imbalance increase increase in Inpatient Inpatients intensive care intensive care unit lead lowest marker mechanism Medical conditions Non-COVID-19 Patient patients with COVID-19 plasma predict Prospective Study prothrombotic state recruited reduction reduction in thrombotic thrombotic risk von Willebrand factor vWF were measured with COVID-19 [DOI] 10.1007/s11239-021-02457-9 PMC 바로가기 [Article Type] Article
Machine Learning Approaches to Identify Patient Comorbidities and Symptoms That Increased Risk of Mortality in COVID-19Article Published on 2021-07-312022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age and gender Analysis assist association Asthma cardiovascular disease Care caused Cerebrovascular disease chronic obstructive CKD Cohort combinations Comorbidities Comorbidity condition COPD COVID-19 COVID-19 patient CVD dataset Deceased Determining feature highlight hospital resources hypertension implication Increased individual machine machine learning malignancy Meta-analysis morbidity and mortality Mortality mortality risk pandemic performed Predictive predictor Providing pulmonary disease respiratory risk SARS-CoV-2 SARS-CoV-2 virus severe symptom severity significantly suggested symptom severity the disease the patient those who survived type 2 diabetes while with COVID-19 [DOI] 10.3390/diagnostics11081383 PMC 바로가기 [Article Type] Article
Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers의료 종사자의 AZD1222/Covishield 백신 단일 용량에 대한 면역 반응Article Published on 2021-07-292022-09-10 Journal: Nature Communications [Category] SARS, 변종, 진단, 치료기술, [키워드] ACE2 Adaptive immunity age and gender antibody antibody level antibody levels Antibody titer Antibody titers approval AZD1222 B.1.1.7 B.1.351 B.1.351 variant blocking antibodies carried Cohort COVID-19 vaccine dose ELISpot assay ELISpot assays Ex vivo HCW HCWs Health care Health care worker health care workers Health occupations healthcare worker Healthcare workers IFNγ immunogenicity large cohort naïve Neutralization assay PROTECT RBD Receptor binding domain response SARS-CoV-2 Seroconversion seroconvert seroconverted significantly higher single dose sub-cohort sVNT T cell T cell response the RBD titre titres Vaccine vaccine dose vaccinees Vaccines variant variants wild-type SARS-CoV-2 wild-type virus [DOI] 10.1038/s41467-021-24579-7 PMC 바로가기 [Article Type] Article
Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infectionCOVID-19 환자에서 변경된 MicroRNA 발현은 SARS-COV-2 감염의 확인을 가능하게합니다.Research Article Published on 2021-07-282022-08-13 Journal: PLoS Pathogens [Category] SARS, 신종인플루엔자, 유전자 메커니즘, 진단, 치료기술, [키워드] Accuracy age and gender Altered applied artificial intelligence artificial intelligence methodology bioinformatics circulating miRNA circulating miRNAs COVID-19 COVID-19 case COVID-19 cases COVID-19 patient COVID-19 patients Critical defined detect disease down-regulated expression H1N1 healthy control healthy controls healthy donors Host host miRNA host miRNA response host molecule host response host-encoded microRNA identify IMPROVE induce Infection Inflammatory Influenza influenza A machine learning analysis management microRNA miR-1275 miR-195-5p miR-23a-3p miR-31-5p miR-3215-3p miR-423-5p miR-4742-3p miR-776-3p miR423 miR423-5p miRNA miRNA profile miRNA signature miRNAs Next-generation sequencing outcome Oxygenation Patient Patient management plasma profile robust SARS-COV-2 infection severity Supervised machine learning analysis up-regulated upregulated Viral viral pathogenesis was used while [DOI] 10.1371/journal.ppat.1009759 PMC 바로가기 [Article Type] Research Article
COVID-19 pandemic related long-term chronic stress on the prevalence of depression and anxiety in the general populationResearch Published on 2021-07-282022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] age and gender Anxiety anxiety symptom association changes in chi-square test conducted consequence correlated COVID-19 COVID-19 pandemic cross-sectional demographic data Depression depressive Depressive symptoms discrepancy Effect enrolled evaluate Factor Factors GAD-7 General population Health Impact Insomnia intrinsic ISI Logistic regression analysis Long-term stress mental health mental health problem outbreak pandemic participant Patient Pearson PHQ-9 physical potential risk Prevalence protective factor Psychological questionnaire reaction Result risk factor severity significantly Stress supplementary material Symptom Symptoms variable were measured [DOI] 10.1186/s12888-021-03385-x PMC 바로가기 [Article Type] Research
COVID-19 pandemic related long-term chronic stress on the prevalence of depression and anxiety in the general populationResearch Published on 2021-07-282022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, SARS, [키워드] age and gender Anxiety anxiety symptom association changes in chi-square test conducted consequence correlated COVID-19 COVID-19 pandemic cross-sectional demographic data Depression depressive Depressive symptoms discrepancy Effect enrolled evaluate Factor Factors GAD-7 General population Health Impact Insomnia intrinsic ISI Logistic regression analysis Long-term stress mental health mental health problem outbreak pandemic participant Patient Pearson PHQ-9 physical potential risk Prevalence protective factor Psychological questionnaire reaction Result risk factor severity significantly Stress supplementary material Symptom Symptoms variable were measured [DOI] 10.1186/s12888-021-03385-x PMC 바로가기 [Article Type] Research
Sleep quality among undergraduate students of a medical college in Nepal during COVID-19 pandemic: an online surveyResearch Article Published on 2021-07-212022-10-31 Journal: F1000Research [Category] Coronavirus, MERS, SARS, [키워드] activities Adjusting age age and gender analyzed average changes in collected conducted COVID-19 COVID-19 pandemic cross-sectional detrimental effect Endocrine female Good Health immune changes index less Logistic regression analysis male medical students Mental Nepal outcome persist physical Pittsburgh poor quality positive Psychological Quality Quality of life questionnaire raised random Result shown significantly higher Sleep sleep deprivation sleep quality Stata stratified total score was used worsening [DOI] 10.12688/f1000research.53904.2 PMC 바로가기 [Article Type] Research Article
Age and Gender Disparities in Adverse Events Following COVID-19 Vaccination: Real-World Evidence Based on Big Data for Risk ManagementMedicine Published on 2021-07-192022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Adverse adverse event AEs age age and gender coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccine death disparity Emergency use authorization female females Gender Hospitalization male mRNA vaccines Older real-world data Real-world study reported Reporting Safe serious AEs System Vaccine vaccine adverse event reporting system [DOI] 10.3389/fmed.2021.700014 PMC 바로가기 [Article Type] Medicine
An artificial neural network model to predict the mortality of COVID-19 patients using routine blood samples at the time of hospital admission: Development and validation study입원 시 일상적인 혈액 샘플을 사용하여 COVID-19 환자의 사망률을 예측하는 인공 신경망 모델: 개발 및 검증 연구Multicenter Study Published on 2021-07-162022-09-11 Journal: Medicine [Category] SARS, 바이오마커, [키워드] age and gender ANN applied Artificial neural network AUC Biomarker Blood blood sample Care characteristic classification CNN Convolutional neural network COVID-19 COVID-19 patient COVID-19 patients dataset demographic variable develop development downloaded early stage forest plot Google maps Health Health care help high mortality hospital Hospital admission IMPROVE in-hospital mortality Korean Laboratory Mortality name normalized pandemic parameter Patient patient records patients predict Probability receiver receiver operating characteristic retrieved risk sensitivity shown specificity training data Treatment validation study variable Wuhan Wuhan, China [DOI] 10.1097/MD.0000000000026532 PMC 바로가기 [Article Type] Multicenter Study
Impact of Coronavirus Disease 2019 Pandemic on Crowding: A Call to Action for Effective Solutions to “Access Block”Observational Study Published on 2021-07-162022-10-04 Journal: Western Journal of Emergency Medicine [Category] 임상, [키워드] Action age and gender baseline Care changes in Clinical data Complete conditions coronavirus disease COVID-19 COVID-19 pandemic crowding disease emergency department Epidemic foundation healthcare hospital Hospitalization identification Impact involved IRCCS Italy lack management Matteo occur outbreak pandemic Pandemics Patient Pavia per day Policlinic Prevent reduced required Result retrospective solution Treatment vital signs Volume [DOI] 10.5811/westjem.2021.2.49611 PMC 바로가기 [Article Type] Observational Study