Mechanism of Caspase-1 Inhibition by Four Anti-inflammatory Drugs Used in COVID-19 TreatmentCOVID-19 치료에 사용되는 4가지 항염증제에 의한 Caspase-1 억제 메커니즘Article Published on 2022-02-062022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, 치료제, [키워드] “cytokine storm” active site activity alleviate Amino acid analyzed anti-inflammatory drug Anti-inflammatory drugs antioxidant carbonyl caspase caspase-1 cause causes Colchicine Compound Computational methods Corticosteroid covalent bond COVID-19 COVID-19 infection COVID-19 therapy COVID-19 treatment cytokine cytokine release Cytokine storm Cytokines death Dexamethasone drug drugs effective excessive cytokine production help indicated Inflammatory Inflammatory response inhibition inhibitor mechanism Methylprednisolone molecular protease protons raloxifene reported residue scavenging Superoxide therapy these compounds transfer Treatment Trigger triggers [DOI] 10.3390/ijms23031849 PMC 바로가기 [Article Type] Article
Continuous Renal Replacement Therapy With oXiris Filter May Not be an Effective Resolution to Alleviate Cytokine Release Syndrome in Non-AKI Patients With Severe and Critical COVID-19Pharmacology Published on 2022-02-042022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Admission alanine aminotransferase ALB albumin alleviate ALT Aspartate aminotransferase AST C-reactive protein circulating cytokine clinical collected Concentration Continuous Continuous renal replacement therapy control group coronavirus disease COVID-19 Critical CRP CRRT CRS Cytokine release syndrome Cytokine storm demographic determine fibrinogen Filter hospital Hospitalization hyper inflammation ICU IFN-γ IL-10 IL-2 IL-4 IL-6 individual inflammatory chemokines intervention group IRB lymphocyte Lymphocyte count medical records medical system neutrophil no significant difference non-acute kidney injury Organ failure oXiris filter Patient Platelet proportion Protein random number table randomly divided Release renal replacement therapy replacement Resolution SARS-COV-2 infection sensitivity serum creatinine severe and critical COVID-19 severity of COVID-19 significantly significantly higher significantly lower SOFA strained TNF-α total bilirubin treated Treatment two groups WBC White blood cell [DOI] 10.3389/fphar.2022.817793 PMC 바로가기 [Article Type] Pharmacology
sRAGE alleviates SARS-CoV-2-induced pneumonia in hamstersRAGE, 햄스터에서 SARS-CoV-2 유발 폐렴 완화Letter Published on 2022-02-022022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), MERS, SARS, 진단, 치료제, [키워드] alleviate Infectious diseases Pneumonia Translational research [DOI] 10.1038/s41392-022-00883-6 PMC 바로가기 [Article Type] Letter
Fatty liver on computed tomography scan on admission is a risk factor for severe coronavirus disease입원 시 컴퓨터 단층 촬영에서 지방간은 심각한 코로나 바이러스 질병의 위험 요소입니다Article Published on 2022-02-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 치료기술, [키워드] Admission alleviate Asymptomatic Care clinician Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 guidelines COVID-19 patient COVID-19 patients COVID-19 severity criteria CT scan evaluate evaluated Factor Fatty liver groups had no help hospital hospitals invasive Japanese less liver Logistic regression analysis median median age Mild moderate multivariate multivariate logistic regression analysis occurred outcome overflow Patient patients performed Pneumonia required retrospective cohort study risk factor severe coronavirus disease severe COVID-19 significantly Triage was performed [DOI] 10.1016/j.jiac.2021.10.013 PMC 바로가기 [Article Type] Article
The Role of Ionizing Radiation for Diagnosis and Treatment against COVID-19: Evidence and ConsiderationsReview Published on 2022-01-292022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] alleviate Anti-inflammatory effects anti-inflammatory treatment Cancer cardiac disease Chest CT Clinical use Computed tomography Coronavirus disease 2019 COVID-19 COVID-19 patient deaths decrease diagnostic effective Evidence health worker healthcare identify imaging ionizing radiation life-threatening low dose low dose radiation therapy (LDRT) management pandemic patients Pneumonia Radiation radiation therapy Radiotherapy risk role Spread Symptom the disease treat Treatment [DOI] 10.3390/cells11030467 PMC 바로가기 [Article Type] Review
No evidence that mask-wearing in public places elicits risk compensation behavior during the COVID-19 pandemicArticle Published on 2022-01-272022-10-04 Journal: Scientific Reports [Category] SARS, 치료법, [키워드] Affect alleviate Analysis approach association Compliance COVID-19 pandemic elicit Epidemiology evaluate the effect Evidence face increase Infectious diseases Mask mitigate positive Protective public health measures reduce reduction risk significantly social distancing tested [DOI] 10.1038/s41598-022-05270-3 PMC 바로가기 [Article Type] Article
Can the Market Recognize the Value of the Corporate Governance Mechanism of Chinese Listed Companies?—Empirical Evidence From COVID-19Public Health Published on 2022-01-262022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] alleviate board structure Can Chinese Corporate governance COVID-19 COVID-19 epidemic effective events executive Governance immune management managerial compensation mechanism mechanisms ownership structure Perspective recognize Shock stock price the epidemic value [DOI] 10.3389/fpubh.2021.812253 PMC 바로가기 [Article Type] Public Health
The Evolution and Disparities of Online Attitudes Toward COVID-19 Vaccines: Year-long Longitudinal and Cross-sectional StudyObservational Study Published on 2022-01-212022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] accelerate age Algorithm alleviate Analysis Attitude can be used caused Characteristics collected concerning conducted confirmed case correlated COVID-19 COVID-19 pandemic COVID-19 vaccine Critical cross-sectional Data mining deaths deep learning defined demographic characteristics dimension disparity Efficacy events Evolution expressed Government group groups help individual longitudinal male males mechanism media objective Older organization pandemic Pearson population group promote public health public health authority Result second suggested targeted intervention Twitter urgency Vaccine Vaccines [DOI] 10.2196/32394 PMC 바로가기 [Article Type] Observational Study
COVID-19 and Its Lockdown in Belgium: How Limited Access to Environmental Satisfaction Impacts Emotions?Research Article Published on 2022-01-202022-10-28 Journal: Psychologica Belgica [Category] COVID-19, [키워드] access activity adaptive addressed alleviate Anxiety consequence COVID-19 COVID-19 pandemic decrease emotions Environmental Satisfaction General population Impact increase in increases in individual induce less Limited lockdown measure negative and positive negative emotion negative emotions pandemic positive Positive emotion Psychological psychological Impact Quality of life Regulation Research Result Satisfaction shown Stress turn [DOI] 10.5334/pb.1082 PMC 바로가기 [Article Type] Research Article
Clinical efficacy of iodine complex in SARS-CoV-2-infected patients with mild to moderate symptoms: study protocol for a randomized controlled trial경증에서 중등도의 증상을 보이는 SARS-CoV-2 감염 환자에서 요오드 복합체의 임상 효능: 무작위 대조 시험을 위한 연구 프로토콜Update Published on 2022-01-192022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] adaptive addition alleviate analyzed Arm benefit both groups caused Chest clinic clinical clinical trial collected Combination complex Computed tomography conducted coronavirus disease Coronavirus disease 2019 Coronavirus-2 country COVID-19 COVID-19 patient COVID-19 patients doctor Efficacy High-resolution Hospitalization HRCT implication IMPROVE in both groups Intervention Iodine lower mortality Mild mild to moderate mild to moderate symptoms moderate Mortality Novel coronavirus pandemic parallel group parameter Patient Placebo placebo-controlled Polymer questionnaire radiological improvement Randomized controlled trial randomized trial receive reduction in respiratory respiratory syndrome coronavirus RT-PCR Sample size SARS-CoV-2 SARS-CoV-2-infected patient SAS version 9.4 severe respiratory syndrome socioeconomic status standard care Study protocol symptomatic Symptoms syrup Treatment treatment of COVID-19 Trial Trial registration Viral Viral load viral load reduction with COVID-19 written consent [DOI] 10.1186/s13063-021-05848-8 PMC 바로가기 [Article Type] Update