Neutralizing antibody responses against SARS-CoV-2 spike receptor-binding domain 13 months after the recovery from the diseaseObservational Study Published on 2022-05-012023-07-06 Journal: Annali di igiene : medicina preventiva e di comunità [Category] COVID19(2023년), [키워드] Antibody responses coronavirus COVID-19 Immunity SARS-CoV-2 [DOI] 10.7416/ai.2021.2466 [Article Type] Observational Study
B Cell Aplasia Is the Most Powerful Predictive Marker for Poor Humoral Response after BNT162b2 mRNA SARS-CoV-2 Vaccination in Recipients of Allogeneic Hematopoietic Stem Cell TransplantationB 세포 무형성은 동종 조혈모세포 이식 환자에서 BNT162b2 mRNA SARS-CoV-2 백신 접종 후 불량한 체액 반응에 대한 가장 강력한 예측 마커입니다Article Published on 2022-05-012022-09-11 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] 95% confidence interval absence administration age allo-HSCT Allogeneic allogeneic hematopoietic stem cell transplantation Analysis analyzed anti-SARS-CoV-2 vaccination Antibody Response Antibody responses aplasia B cell B cells B-cell BNT162b2 BNT162b2 mRNA CD4 CD8 characteristic close monitoring Cohort COVID-19 Donor Efficacy entire cohort evaluate evaluated Factor hematopoietic Hematopoietic stem cell highest HSCT humoral Humoral response immune response Immune status Immunosuppressed immunosuppressed patients injection lymphocyte Lymphocyte count lymphopenia median MOST mRNA natural killer cell Natural killer cells Odds ratio of BNT162b2 Patient Poor predict provided recipient recipients reported responders response response rate SARS-CoV-2 SARS-CoV-2 mRNA SARS-CoV-2 vaccination SARS-CoV-2 vaccine Specific STEM stem cell Stem cell transplantation T cell T cells the antibody response transplantation Treatment Univariate analysis Vaccine were assessed [DOI] 10.1016/j.jtct.2022.02.018 PMC 바로가기 [Article Type] Article
Rapid Quantitative Point-Of-Care Diagnostic Test for Post COVID-19 Vaccination Antibody Monitoring코로나19 백신 접종 후 항체 모니터링을 위한 신속한 정량적 현장 진료 진단 테스트Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] agreement analyzed Antibody Response Antibody responses Antibody Units assays binding antibody unit capillary blood chemiluminescence CLIA CLIA analyzer correlation correlation coefficient COVID-19 COVID-19 pandemic demonstrated diagnostic DiaSorin evaluate evaluated expressed high correlation IgG immune response immune responses immunoassay immunomagnetic agglutination assay individual Infection Laboratory laboratory assays lateral flow LIAISON monitoring performed plasma plasma sample plasma samples POC POC test point-of-care quantification Quantitative Rapid rapid IgG-IgM-IgA combined test Result S protein S protein trimer S1/S2 SARS-CoV-2 SARS-CoV-2 IgM SARS-CoV-2 spike SARS-CoV-2 spike protein sensitivity Serological testing serology test Spearman Spike protein Support Test Total total antibodies total antibody Trimeric spike protein vaccination venous were measured Whole blood [DOI] 10.1128/spectrum.00396-22 PMC 바로가기 [Article Type] Article
Seroreactivity of the Severe Acute Respiratory Syndrome Coronavirus 2 Recombinant S Protein, Receptor-Binding Domain, and Its Receptor-Binding Motif in COVID-19 Patients and Their Cross-Reactivity With Pre-COVID-19 Samples From Malaria-Endemic AreasCOVID-19 환자에서 중증 급성 호흡기 증후군 코로나바이러스 2 재조합 S 단백질, 수용체 결합 도메인 및 이의 수용체 결합 모티브의 혈청반응성과 말라리아 발병 지역의 코로나19 이전 샘플과의 교차 반응성Article Published on 2022-04-272022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 말라리아, 진단, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition age anti-S antibody antibody Antibody Response Antibody responses Antigen antigens Area Asthma blood sample Blood samples Community Comorbidities conducted coronavirus coronavirus 2 COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 samples cross-reactive antibody cross-reactivity determine diabete diabetes disease Donor ELISA full-length Gender hospital IgG antibodies IgG antibody individual malaria malaria endemic-area participant Patient Plasmodium falciparum Plasmodium falciparum infection Pre-COVID-19 samples Protein RBD RBM Receptor-binding domain receptor-binding motif Recognition Recombinant S regions respiratory response responses S protein Sample SARS-CoV-2 SARS-CoV-2 proteins SARS-CoV-2 S SARS-CoV-2 S protein sera seroreactivity severe acute respiratory syndrome Coronavirus Study participants tested the receptor-binding domain the SARS-CoV-2 Treatment triggered weakened West while [DOI] 10.3389/fimmu.2022.856033 PMC 바로가기 [Article Type] Article
Broad Neutralization of SARS-CoV-2 Variants, Including Omicron, following Breakthrough Infection with Delta in COVID-19-Vaccinated IndividualsCOVID-19 백신을 접종한 개인의 Delta에 대한 획기적인 감염에 따른 오미크론을 포함한 SARS-CoV-2 변이체의 광범위한 중화Article Published on 2022-04-262022-09-11 Journal: mBio [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Antibody Response Antibody responses AZD1222 B.1.1.529 B.1.617.2 BNT162b2 breadth Breakthrough infection COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cross-neutralizing Delta effective ENhance Evidence evidence of greater hospitalizations IgG immunization Impact in some Including individual Infection magnitude neutralization neutralization breadth neutralizing antibody Neutralizing antibody response neutralizing antibody responses Numerous occur omicron Omicron variant population immunity potency priming provide Rapid reducing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variant SARS-CoV-2 variants shown the antibody response Transmission vaccinated individuals Vaccine vaccinees variant variants of concern [DOI] 10.1128/mbio.03798-21 PMC 바로가기 [Article Type] Article
Immunogenicity of Inactivated SARS-CoV-2 Vaccines in Patients With Rheumatoid Arthritis: A Case Series류마티스 관절염 환자에서 비활성화된 SARS-CoV-2 백신의 면역원성: 사례 시리즈Article Published on 2022-04-252022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] (C-reactive protein age analyzed antibody Antibody Response Antibody responses Arthritis Autoimmune disease C-reactive protein C-RP calculated CCP chemiluminescence Chinese Community COVID-19 disease dose ELISA ELISA kit erythrocyte sedimentation erythrocyte sedimentation rate ESR FIVE healthy control healthy subjects humoral IgG immune response immune responses immunofluorescence immunogenicity immunoturbidimetry in some inactivated inactivated SARS-CoV-2 vaccines Inactivated vaccine indirect immunofluorescence lowest lymph Medicine mRNA Neutralizing Neutralizing antibodies neutralizing antibody Neutrophils no correlation not differ Patient patients peptide Protein receiving recruited reported Rheumatoid rheumatoid arthritis rheumatoid factor SARS-CoV-2 SARS-CoV-2 vaccine sedimentation rate Sery significantly lower Spearman correlation analysis Test Traditional Traditional Chinese medicine vaccination Vaccines was used were measured [DOI] 10.3389/fpubh.2022.875558 PMC 바로가기 [Article Type] Article
Long-term persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific and neutralizing antibodies in recovered COVID-19 patients중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2)가 장기간 지속되면 회복된 COVID-19 환자에서 단백질 특이성 및 중화 항체가 급증합니다.Article Published on 2022-04-212022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-RBD anti-receptor-binding domain Anti-spike Antibody Response Antibody responses Antibody titers Asymptomatic individuals blood sample Blood samples Cohort cohort of patient collected confirmed case coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 disease enrolled half-life IgA IgG IgG antibody IgG antibody titer Immunoglobulin immunological individual Infection Mild Mild disease Neutralizing neutralizing antibody Neutralizing titer neutralizing titers participant persistence Protein RBD recovered COVID-19 patient Recovered COVID-19 patients remained respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein Seropositivity serum antibody severe disease significantly Support symptom onset symptom severity total Ig understanding Vaccine wild-type SARS-CoV-2 [DOI] 10.1371/journal.pone.0267102 PMC 바로가기 [Article Type] Article
Early and strong antibody responses to SARS-CoV-2 predict disease severity in COVID-19 patientsSARS-CoV-2에 대한 초기의 강력한 항체 반응은 COVID-19 환자의 질병 중증도를 예측합니다Article Published on 2022-04-152022-09-11 Journal: Journal of Translational Medicine [Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료법, [키워드] antibody antibody levels Antibody profile Antibody Response Antibody responses Antibody-dependent enhancement Antigen Antigen microarray Biomarker Candidates cell activation Clinical significance correlated COVID-19 COVID-19 patient disease disease severity elicit epidemiological studies exacerbate frequencies Frequency full length healthy controls idea IgA IgA response IgA responses IgE IgG IgM response IgM responses implication levels of antibody mast cell Mast cells Mild disease MOST nonstructural protein nucleocapsid Pathogenesis pathogenesis of COVID-19 Patient patients with COVID-19 peak levels Planning predict Prevalence Prognosis prognostic Protein recent response Result risk S protein SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens sera serological studies SEROLOGICAL STUDY Serum level severe disease severity Spread Support testing antibody the disease the vaccine vaccine candidates virus with mild disease [DOI] 10.1186/s12967-022-03382-y PMC 바로가기 [Article Type] Article
Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays반정량적 항SARS-CoV-2 항체 면역분석법의 중화 효과 및 역가 상관관계 추정Article Published on 2022-04-142022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료법, 치료제, [키워드] Anti-RBD IgG anti-SARS-CoV-2 antibody antibodies antibody Antibody responses antibody tests assays best Chemiluminescent assay comparable convalescent phase correlated correlation COVID-19 cut-off Effect evaluated IgG antibodies IgG antibody immunoassay infections investigated linear linear correlation neutralization test Neutralizing Neutralizing activity neutralizing antibody nucleocapsid protein nucleopcapsid (NP) protein Pearson plaque reduction neutralization Plaque reduction neutralization test PRNT Protein RBD Receptor-binding domain SARS-CoV-2 SARS-COV-2 infection semi-quantitative sensitivity serology specificity spike (S) protein Spike protein sVNT the RBD the receptor-binding domain the spike protein titer total antibodies total antibody virus neutralization test [DOI] 10.3389/fcimb.2022.822599 PMC 바로가기 [Article Type] Article
mRNA vaccination in octogenarians 15 and 20 months after recovery from COVID-19 elicits robust immune and antibody responses that include OmicronCOVID-19에서 회복된 후 15개월 및 20개월 후 80세 여성에서 mRNA 백신 접종은 Omicron을 포함한 강력한 면역 및 항체 반응을 이끌어냅니다Article Published on 2022-04-122022-09-11 Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin angiotensin-converting enzyme 2 antibody Antibody binding antibody levels Antibody Response Antibody responses BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine BNT162b2 vaccine boost Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CP: Microbiology cytokine doses elicit Genetic heavy chain high-risk population IgG IGHV IGHV clones immune Immune transcriptome Immunoglobulin Immunoglobulin G include individual Infection interferon Microbiology mRNA vaccination mRNA vaccine naïve individuals naive versus COVID-19-recovered individuals neutralization Neutralizing antibodies neutralizing antibody octogenarian. of BNT162b2 omicron PBMC receiving respiratory response RNA sequencing RNA-Seq robust SARS-CoV-2 SARS-CoV-2 spike-specific single dose sustained transcript Transcriptome vaccination Vaccine vaccine dose vulnerable population [DOI] 10.1016/j.celrep.2022.110680 PMC 바로가기 [Article Type] Article