High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms
고위험군 분리가 두개내 동맥류에 걸리기 쉬운 저주파 변이를 나타냅니다
Research Article
[키워드] Aneurysm
arteries
Artery
association
Author
balloon
bleeding
bottleneck events
Brain
Case-control
cause
compared
complex
complex diseases
contribute
Control
controls
develop
different
disease
effect size
effect sizes
European population
events
explain
explained
Families
Finn
Finnish
Finns
FIVE
fraction
frequencies
Frequency
genetic background
Genetic variant
Genetic variation
genotype imputation
GWAS
hemorrhage
heritability
identify
incidence
Inconclusive
Intracranial
intracranial aneurysms
isolate
isolates
knowledge
lead
life-threatening
loci
locus
low frequency
MAF
matched controls
Netherland
Netherlands
Patient
Population
populations
rare variant
Rare variants
related
replicated
rupture
saccular
stroke
Study design
Subarachnoid
subarachnoid hemorrhage
susceptibility
tested
utility
variant
variants
[DOI] 10.1371/journal.pgen.1004134 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1004134 PMC 바로가기 [Article Type] Research Article