Could BCG Vaccination Induce Protective Trained Immunity for SARS-CoV-2?Immunology Published on 2020-05-082022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] analyzed BCG BCG vaccination caused children Contagion correlated country COVID-19 death deaths immune response Immunity Inclusion induce Infection Innate immunity Mortality Mycobacterium tuberculosis National non-specific pandemic pathogen Pathogens positive PROTECT public health reduce SARS-CoV-2 SARS-CoV-2 pandemic shown thought trained immunity Treatment Tuberculosis vaccination Vaccine Vaccines variety [DOI] 10.3389/fimmu.2020.00970 PMC 바로가기 [Article Type] Immunology
Safety and Immunogenicity of Newborn MVA85A Vaccination and Selective, Delayed Bacille Calmette-Guerin for Infants of Human Immunodeficiency Virus-Infected Mothers: A Phase 2 Randomized, Controlled Trial신생아 MVA85A 백신 접종 및 인간 면역결핍 바이러스에 감염된 산모의 유아를 위한 선택적 지연 Bacille Calmette-Guerin의 안전성 및 면역원성: 2상 무작위, 대조 시험Articles and Commentaries Published on 2018-02-152022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, [키워드] acquisition Ag85A age appear ARMS bacille Calmette-Guérin BCG BCG vaccination boost candidate CD4 CD4+ T cell CD4+ T cells CD4+ T-cell clinical control arm Controlled Delayed disease double-blind ENhance enrolled excluded Follow-up followed by functional HIV HIV infection HIV-exposed infants HIV-uninfected Human Human immunodeficiency virus IFNγ immune response immunodeficiency virus immunogenicity Infant interfere interferon gamma life magnitude memory MVA85A New Newborn no significant difference Phase 2 phenotype potential risk profiles PROTECT randomized, controlled trial reactogenicity event Registration response Result Safe Safety selective Serious Adverse Events significantly higher subsequent T cells T-cell Response tested Tuberculosis tuberculosis disease tuberculosis vaccine vaccination Vaccination strategy vaccinees [DOI] 10.1093/cid/cix834 PMC 바로가기 [Article Type] Articles and Commentaries