A novel machine learning model to predict respiratory failure and invasive mechanical ventilation in critically ill patients suffering from COVID-19 Research Published on 2022-06-222022-10-05 Journal: Scientific Reports [Category] 임상, 치료기술, [키워드] Algorithm applied Applying AUC clinician Cohort COVID-19 COVID-19 cohort COVID-19 patient COVID-19 patients Critically ill Critically ill patient database dataset Delayed Features Good hypoxemic ICU IMV Invasive mechanical ventilation laboratory result Non-COVID-19 outcome outcomes Patient Precision predict predicted Predictive Predictive model Probability required Respiratory failure risk single center tested the United State transfer translate variables were used [DOI] 10.1038/s41598-022-14758-x [Article Type] Research
IL-1 and autoinflammatory disease: biology, pathogenesis and therapeutic targeting Reviews Published on 2022-06-212022-10-05 Journal: Nature reviews. Rheumatology [Category] 바이오마커, 변종, 유전자 메커니즘, [키워드] approaches autoinflammatory disease cells characterized clinical feature clinical response clinician conditions diagnostic Diseases disorder dysregulation epidemiological Fever Genotype IL-1 include innate immune innate immune system mechanism mouse model mutant over Pathogenesis pathogenic mutations pathophysiological Patient patients Perspective Phenotypes regulated rheumatologist specific diseases subsequent syndrome systemic inflammation targeted therapy therapeutic targeting therapy [DOI] 10.1038/s41584-022-00797-1 [Article Type] Reviews
Nationwide Harmonization Effort for Semi-Quantitative Reporting of SARS-CoV-2 PCR Test Results in Belgium벨기에 SARS-CoV-2 PCR 검사 결과 반정량적 보고를 위한 전국적인 조화 노력Article Published on 2022-06-142022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] absence affected Asymptomatic Belgium calculated category clinician Concentration Contact tracing Course cycle threshold database determine driven by effort Factors harmonization indications Infection Infectivity information Laboratory Leuven National National Reference Centre pandemic PCR PCR assay positive PCR result Reporting Result resulting RNA RNA copies/mL SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 test semi-quantitative semi-quantitative PCR semi-quantitative reporting. serological standard curve Standard deviation target gene Test the mean threshold to define viral shedding [DOI] 10.3390/v14061294 PMC 바로가기 [Article Type] Article
Clinical care pathway for the evaluation of patients with suspected VITT after ChAdOx1 nCoV-19 vaccinationChAdOx1 nCoV-19 백신 접종 후 VITT가 의심되는 환자의 평가를 위한 임상 치료 경로Article Published on 2022-06-142022-09-12 Journal: Blood advances [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome adenoviral vector adenoviral vector vaccine antibodies antibody Anticoagulants Canada Care ChAdOx1 nCoV-19 clinical clinical care clinician coronavirus Corticosteroids demonstrated ELISA enzyme-linked immunosorbent FEU fibrinogen immune Immunoglobulin investigated optical pathway Patient PF4 Platelet platelet counts positive presenting SARS-CoV-2 Serotonin significantly SRA Symptom thrombosis thrombotic treated vaccination [DOI] 10.1182/bloodadvances.2021006862 PMC 바로가기 [Article Type] Article
Effect of thermal and chemical treatments used for SARS-COV-2 inactivation in the measurement of saliva analytes Research Published on 2022-06-082022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] affected affecting Biomarkers can be used clinician condition Effect Electrophoresis Enzymes evaluated expression levels Glucose help inactivation metabolism NP-40 oxidative Protein protocol researcher Safe Saliva salivary SARS-CoV-2 SDS SDS-PAGE specific biomarker Stress tested tissue damage Treatment Triglyceride Triton X-100 [DOI] 10.1038/s41598-022-13491-9 [Article Type] Research
Anti-inflammatory response of cardamom extract and prediction of therapeutic window in COVID-19 patients by assessing inflammatory markers using RT-PCRRT-PCR을 사용한 염증 마커를 평가함으로써 COVID-19 환자에서 카 다몬 추출물의 항 염증 반응 및 치료 창의 예측Article Published on 2022-06-012022-08-31 Journal: Inflammopharmacology [Category] COVID19(2023년), MERS, SARS, 진단, 치료제, [키워드] addition alternative Anti-inflammatory anti-inflammatory action anti-inflammatory response Anti-viral association attending physician Awareness breathlessness can not Cardamom Clinical improvement Clinical practice clinician control group cough Course COVID-19 COVID-19 patient COVID-19 patients COVID-19 symptom COVID-19 symptoms CRP Ct values cycle threshold cytokine Cytokine storm dawn Diagnostic method diagnostic test diagnostic tests disease Disease progression dosage dose effective elevated end point enrolled Fever FORTE gene expression profile hospital IL-10 IL-6 India indicate Inflammation Inflammatory marker inflammatory markers inflammatory parameter intake Intervention lack LDH majority material molecular diagnostics morbidity morbidity and mortality multiplex negativity normalized onset of symptom outcome parameter Patient patients PCR test performed popularity potentiality predict Prednisolone prevalent Prognosis protein level provide reason for reducing reported RT-PCR RT-PCR analysis RT-PCR assay RT-PCR test SARS-CoV-2 SARS-CoV-2 RT-PCR SARS-CoV-2 RT-PCR test serum Serum IL-6 sore throat Standard of care standard treatment Steroids Symptom Tablet tested the cytokine storm the patient therapeutic window time TNF- α Treatment treatment arm treatment group were given worsening [DOI] 10.1007/s10787-022-00951-x PMC 바로가기 [Article Type] Article
Multisystem inflammatory syndrome in children associated with COVID-19 in 101 cases from Turkey (Turk-MISC study)터키에서 발생한 101명의 사례에서 COVID-19와 관련된 어린이의 다기관 염증 증후군(Turk-MISC 연구)Article Published on 2022-06-012022-09-12 Journal: Journal of paediatrics and child health [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Admission age Analysis body mass index C-reactive protein Child children classical clinical Clinical features clinician collected conducted COVID-19 death diagnosed Diagnosis died differential diagnosis elevated erythrocyte sedimentation rate fatigue Fever Gastrointestinal symptom Gender glucocorticoid groups healthy hospital immunomodulatory Inflammatory intensive care interquartile range Intravenous immunoglobulin IQR Kawasaki disease laboratory characteristics management median median age medical record MIS-C Most patient multivariate logistic regression outcome Patient patients PCR polymerase chain positive positive serology predominant procalcitonin level required Retrospective study SARS-CoV-2 Shock syndrome treated Treatment Turkey with COVID-19 [DOI] 10.1111/jpc.15913 PMC 바로가기 [Article Type] Article
Effect of Text Messaging and Behavioral Interventions on COVID-19 Vaccination Uptake: A Randomized Clinical TrialRandomized Controlled Trial Published on 2022-06-012022-10-05 Journal: JAMA Network Open [Category] 임상, [키워드] absolute difference age assigned black Cell clinical clinician conducted COVID-19 COVID-19 vaccine detectable Effect evaluate factorial design first dose group Health health system Hispanic increase in initial intent-to-treat intention-to-treat basis Latino outcome Patient Philadelphia Population primary care Primary outcome proportion randomized clinical trial Randomly receive receiving respond responses secondary text the mean the vaccine Trial trial protocol vaccination vaccine dose white [DOI] 10.1001/jamanetworkopen.2022.16649 PMC 바로가기 [Article Type] Randomized Controlled Trial
Cutaneous Small-vessel Vasculitis after ChAdOx1 COVID-19 Vaccination: A Report of Five CasesChAdOx1 COVID-19 예방접종 후 피부 소혈관염: 5건의 보고Case Reports Published on 2022-06-012022-09-11 Journal: The international journal of lower extremity wound [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome adverse event Affect Antihistamines arteries Arterioles Autoimmunity Capillaries ChAdOx1 ChAdOx1 COVID-19 vaccine clinician coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination Cutaneous Cutaneous Small-vessel Vasculitis defined demonstrated detectable FIVE lesion lower limb lower limbs Methylprednisolone one patient organs pandemic Pathogenesis Patient pregnant women reaction report reported required SARS-CoV-2 Severe acute respiratory syndrome small blood vessels South Korea spread to Steroids Symptom upper limb upper limbs vaccination Vasculitis women [DOI] 10.1177/15347346221078734 PMC 바로가기 [Article Type] Case Reports
Clinical update on COVID-19 for the emergency and critical care clinician: Medical management응급 및 중환자 진료의를 위한 COVID-19에 대한 임상 업데이트: 의료 관리Review Published on 2022-06-012022-09-11 Journal: The American journal of emergency medicine [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] 2019 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admitted Patient antagonists antivirals Aspirin Care caused Chloroquine clinical clinician Clinicians Colchicine concerning convalescent plasma coronavirus coronavirus disease Coronavirus-2019 COVID-19 Critical care demonstrated disease Emergency Famotidine help Hydroxychloroquine IMPROVE interleukin interleukin-6 introduced Ivermectin kinase inhibitors management mineral Minerals monoclonal antibodies morbidity and mortality outcomes Outpatient outpatients pandemic Patient patients progressed prophylactic anticoagulation provide Randomized respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Steroids Therapies therapy utility variety Vitamin vitamins with COVID-19 [DOI] 10.1016/j.ajem.2022.03.036 PMC 바로가기 [Article Type] Review