In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus InfectionHypothesis Published on 2020-07-262022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory symptom acute respiratory syndrome administration antiviral drugs binding site catalytic Cell Clinical treatment condition Control coronavirus COVID-19 database derivatives DNA damage DRUDIT web service drug Ebola endogenous explain greater health emergency HIV HIV-protease Hypothesis in silico Increased Infection inhibitor insight modulation molecular molecular docking NADH nucleotide oxidative stress pandemic protease Protein protocol Remdesivir Ritonavir SARS CoV-2 SARS-CoV-2 main protease selected Structure susceptibility synergy [DOI] 10.3390/v12080805 PMC 바로가기 [Article Type] Hypothesis
Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquineResearch Article Published on 2020-07-082022-10-30 Journal: Molecular Medicine [Category] Coronavirus, SARS, [키워드] Affect affected ATP autophagy cardiovascular disease caspase-1 caused Cell Chloroquine cleaved consolidation COVID-19 derivatives disease Doppler Effect enzyme exacerbated expected expression Extracellular fibrosis Glycolysis immunofluorescence increase Inflammasome Inflammatory inhibitor Ischemia Ischemic muscle isoform Laser Liver injury Lysosomal inhibition mice Microscopy modulated muscle myocytes oxidative phosphorylation oxygen patients with comorbidity Perfusion Protective Protein reduced reductions in Result Signaling significant increases in tibialis anterior treated viral disease was measured [DOI] 10.1186/s10020-020-00190-2 PMC 바로가기 [Article Type] Research Article
Quinoxaline Derivatives as Antiviral Agents: A Systematic ReviewReview Published on 2020-06-162022-10-30 Journal: Molecules [Category] Coronavirus, SARS, [키워드] anticancer Antiviral antiviral activity antiviral drugs Antiviral treatment biological applications biological property Chemistry Compound concerning derivative derivatives Final Focusing form humans molecular target outbreak Outbreaks pathogen quinoxaline review SAR therapeutic potential therapy triggering virus [DOI] 10.3390/molecules25122784 PMC 바로가기 [Article Type] Review
Glycyrrhizic acid derivatives as influenza A/H1N1 virus inhibitorsArticle Published on 2015-03-072023-06-23 Journal: Bioorganic & medicinal chemistry letters [Category] 신종인플루엔자, [키워드] Analogs antivirals derivatives glycyrrhizic acid Influenza A/H1N1 virus [DOI] 10.1016/j.bmcl.2015.02.074 PMC 바로가기 [Article Type] Article
New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities †Article Published on 2011-09-262022-10-30 Journal: Marine Drugs [Category] Coronavirus, [키워드] activity Analysis anti-trypanosomal antiparasitic assigned Axinella cathepsin B cathepsin L Compound cysteine protease derivative derivatives Leishmania major marine sponge New NMR spectroscopy protease protease inhibition SARS-CoV M Streptomyce Streptomyces axinellae Structure tested tetromycin Trypanosoma [DOI] 10.3390/md9101682 PMC 바로가기 [Article Type] Article