Difficulties in Differentiating Coronaviruses from Subcellular Structures in Human Tissues by Electron Microscopy전자 현미경으로 인간 조직의 세포 내 구조에서 코로나바이러스를 구별하는 데 어려움Review Published on 2021-04-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition caused characteristic coated coronavirus coronavirus disease COVID-19 COVID-19 patient cross damage difficulty electron electron microscopy Endoplasmic reticulum Extracellular focus Human investigator investigators less membrane-bound morphologic feature morphologic features multivesicular bodies negative stain nucleocapsid pandemic Particles pathology reported respiratory respiratory infections SARS SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Structure subcellular structures thin sections tissue damage tissues transmission electron microscopy ultrastructure vesicles virus viruses zoonoses [DOI] 10.3201/eid2704.204337 PMC 바로가기 [Article Type] Review
A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2숙주 내 SARS-CoV-2, MERS-CoV 및 SARS-CoV 역학을 비교하는 데 사용되는 정량적 모델은 SARS-CoV-2의 발병 및 치료에 대한 통찰력을 제공합니다.Research Article Published on 2021-03-222022-09-10 Journal: PLoS Biology [Category] SARS, 치료제, [키워드] addition Analysis antiviral drug antiviral drugs antiviral therapies antiviral therapy antivirals appear approach AUC block Combination coronavirus disease Coronavirus disease 2019 COVID-19 cytotoxicity de novo difficulty early treatment Effect effective Efficacy facilitated hosts Impact infected cell infected cells Infection initiated less mathematical mathematical model MERS-CoV mitigate Novel coronavirus novel coronavirus disease outbreak Pathogenesis pathogenesis of SARS-CoV-2 predict promote provide Quantitative reduce reduction in Reproduction number SARS-CoV SARS-CoV-2 SARS-COV-2 infection Scientific community sensitivity significantly statistically symptom onset the timing therapy Treatment treatment initiation unique Viral viral dynamics Viral load virus production was measured [DOI] 10.1371/journal.pbio.3001128 PMC 바로가기 [Article Type] Research Article
The impact of social and physical distancing measures on COVID-19 activity in England: findings from a multi-tiered surveillance system영국의 COVID-19 활동에 대한 사회적 및 물리적 거리두기 조치의 영향: 다계층 감시 시스템의 결과Surveillance Published on 2021-03-182022-09-10 Journal: Eurosurveillance [Category] 치료기술, [키워드] Admission adopted Care changes in circulation coding Community coronavirus coronavirus disease COVID-19 Critical care death detectable difficulty difficulty breathing Early detection early stage early stages Epidemic healthcare services highlighting hospitalisation hospitalisations identify Impact increasingly Influenza Interaction introduced Laboratory limit lockdown median time MONITOR Mortality National Non-pharmaceutical interventions nursing home outbreak Outbreaks physical distancing measure reported respiratory respiratory virus respiratory viruses Result secondary care social distancing Stage Surveillance swabbing symptom onset the disease the epidemic the timing Transmission United Kingdom viruses were used [DOI] 10.2807/1560-7917.ES.2021.26.11.2001062 PMC 바로가기 [Article Type] Surveillance
Stressors, coping, and resources needed during the COVID-19 pandemic in a sample of perinatal women주산기 여성 표본에서 COVID-19 전염병 동안 필요한 스트레스 요인, 대처 및 자원Research Article Published on 2021-03-012022-09-10 Journal: BMC Pregnancy and Childbirth [Category] SARS, 치료기술, [키워드] Analysis Care coping coping behaviors counseling COVID-19 COVID-19 pandemic Demographic variables detect difficulty during pregnancy Effect engage Ethnicity expressed family Formula friends groups Health Health disparities healthcare Healthcare provider healthcare providers healthy hospital information less Linear regression model mental health Obstetric outcomes Parenting participant Participants Patient Perinatal Postpartum Pregnancy pregnant pregnant women prenatal prevalent Psychological stress Qualitative Quantitative question Racial reported Research resource resources response Result Safe Social support socioeconomic status Stress Stressor stressors supplementary material Support support groups Telemedicine telephone The United States United States was used were used women [DOI] 10.1186/s12884-021-03665-0 PMC 바로가기 [Article Type] Research Article
Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients입원하지 않은 COVID-19 환자의 SARS-CoV-2 및 계절성 코로나바이러스에 대한 항체 반응Research Article Published on 2021-02-242022-09-10 Journal: mSphere [Category] MERS, 진단, 치료기술, 치료법, 치료제, [키워드] 229E addition addressed ADE antibody Antibody Response antibody response against Antibody responses Antibody-dependent enhancement antibody-dependent enhancement (ADE) Asymptomatic breadth conducted contribute coronavirus coronavirus 229E correlated Course COVID-19 cross-protection detect develop diagnostic diagnostic test difficulty Dilution disease experiments highlight Hospitalization human cell human cells Immunity individual infected individuals Infection involved majority marker Mild neutralization Neutralizing activity Neutralizing antibodies Neutralizing antibody response neutralizing antibody responses nucleocapsid Patient phenomenon positive predictor quantified question receptor binding site response S protein SARS-CoV-2 SARS-CoV-2 neutralization seasonal seasonal coronaviruses sera serological Serological assay serological survey Serum Neutralization Spike protein surrogate markers symptomatic targets the S protein the spike protein to define Vaccine development Virus neutralization western blot [DOI] 10.1128/mSphere.01145-20 PMC 바로가기 [Article Type] Research Article
Community practice of using face masks for the prevention of COVID-19 in Saudi Arabia사우디 아라비아에서 COVID-19 예방을 위해 안면 마스크를 사용하는 커뮤니티 관행Clinical Trial Published on 2021-02-192022-08-13 Journal: PLoS ONE [Category] MERS, 임상, [키워드] Administered adopted age analyzed average benefit breathing collected data Community Compliance COVID-19 transmission Demographic variables demographical factors demonstrated difficulty difficulty in breathing discomfort ear pain employment employment status eyeglasse eyeglasses face irritation Face mask face masking Face masks female Frequency Gender group include irritation knowledge media Misconceptions nationality no difference no differences participant prevention of COVID-19 questionnaire reducing reported Saudi Arabia significant difference significant differences social media statistically Variation wearing face mask [DOI] 10.1371/journal.pone.0247313 PMC 바로가기 [Article Type] Clinical Trial
Sleep Conditions Associate with Anxiety and Depression Symptoms among Pregnant Women during the Epidemic of COVID-19 in Shenzhen심천의 COVID-19 전염병 동안 임산부의 불안 및 우울증 증상과 관련된 수면 상태Article Published on 2021-02-152022-09-11 Journal: Journal of affective disorders [Category] 치료제, [키워드] age alleviate Anxiety applied Associate association condition conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional survey declined Depression depressive depressive symptom Depressive symptoms detect difficulty enrolled exhibited generalization help Intervention investigated Logistic regression Mild notable PHQ-9 Pregnancy pregnant women Prevalence proportion Psychiatric Psychiatric symptoms psychological symptoms random referred to remained Research risk SAS Self-Rating Anxiety Scale Shenzhen Sleep sleep quality Standard Standard deviation Symptom targeted interventions the epidemic variable women [DOI] 10.1016/j.jad.2020.11.114 PMC 바로가기 [Article Type] Article
Hydroxychloroquine and COVID-19: a Rheumatologist’s Take on the Lessons LearnedHydroxychloroquine과 COVID-19: 배운 교훈에 대한 류마티스 전문의의 견해Review Published on 2021-01-212022-09-11 Journal: Current allergy and asthma reports [Category] 신약개발, 치료제, [키워드] Antiviral antiviral agent Autoimmune disease Concentration conditions contributing to COVID-19 COVID-19 infection difficulty disease effective endolysosomal exploration Hydroxychloroquine immunomodulation immunomodulatory Infection lesson mechanisms novel SARS-CoV-2 virus other conditions Patient pharmacokinetics potential mechanism Prevent question recent rheumatic disease safety profile SARS-CoV-2 SARS-CoV-2 virus Support target tissue the SARS-CoV-2 virus therapeutic therapeutic effect therapeutic strategy toxicities treat Treatment treatment of COVID-19 use of hydroxychloroquine Variability viral disease [DOI] 10.1007/s11882-020-00983-9 PMC 바로가기 [Article Type] Review
Feeling the Void: Lack of Support for Isolation and Sleep Difficulties in Pregnant Women during the COVID-19 Pandemic Revealed by Twitter Data AnalysisArticle Published on 2021-01-062022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, [키워드] Analysis Anxiety caused change collected concrete COVID-19 COVID-19 pandemic Depressive symptoms difficulty discrepancy distress effort event expressed Factor feeling finding First wave Health individuals International Isolation media mental health mother offered offspring organizations physical Pregnancy problems Psychological Revealed SARS-CoV-2 Sleep social media Stress Support thematic analysis was performed women women’s health [DOI] 10.3390/ijerph18020393 PMC 바로가기 [Article Type] Article
Olfactory Impairment and Close Social Relationships. A Narrative Review후각 장애 및 친밀한 사회적 관계. 내러티브 리뷰Review Published on 2021-01-012022-09-11 Journal: Chemical senses [Category] 치료기술, [키워드] category consequence COVID-19 infection difficulty family friends hygiene impairment implication Infection narrative olfactory olfactory impairment olfactory loss pathogen Pathogens potential mechanism potential mechanisms representing Research review romantic social relationships. Social support Support symptoms of COVID-19 unique [DOI] 10.1093/chemse/bjab037 PMC 바로가기 [Article Type] Review