Periodontal disease and targeted prevention using aMMP-8 point-of-care oral fluid analytics in the COVID-19 eraCOVID-19 시대의 MMP-8 현장 진료 구강액 분석을 사용한 치주 질환 및 표적 예방Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] 바이오마커, [키워드] Alzheimer's disease aMMP-8. approach approaches association Biomarker cardiovascular disease cardiovascular diseases Care Causality chronic obstructive chronic obstructive pulmonary disease complications COVID-19 COVID-19 infections CVD dentist Deterioration diabetes Diagnostic biomarkers disease ENhance equipment examination groups hands Health help hypertension hypothese hypotheses identify inflammatory disease multifactorial Non-invasive obstructive pulmonary disease oral health Patient periodontal periodontal disease Periodontitis point-of-care point-of-care technology point-of-care testing Potential potential biomarkers prevalent prevention professional pulmonary disease risk secondary prevention severe COVID-19 severe COVID-19 infections suggested Support systemic disease systemic diseases Teledentistry [DOI] 10.1016/j.mehy.2020.110276 PMC 바로가기 [Article Type] Article
Structural variations and expression profiles of the SARS-CoV-2 host invasion genes in lung cancer폐암에서 SARS-CoV-2 숙주 침입 유전자의 구조적 변이 및 발현 프로파일Article Published on 2020-11-012022-09-11 Journal: Journal of medical virology [Category] SARS, 변종, 유전자 메커니즘, 치료기술, 치료제, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Amino acid analyses Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Anomaly Basigin binding can be used Cancer CD147 cleaving coronavirus correlation Correlation analysis COVID-19 effective enzyme Evidence evidence of expression expression levels expression profile Features furin Gene Expression Gene expression analysis Genes Genetic genomic groups healthy control Host hypothese hypotheses in silico in silico analysis Invasion Laboratory lung lung adenocarcinoma lung cancer mechanism Mutation pathogenic Patient recent residue respiratory SARS-CoV-2 Serine severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly statistically survival survival analysis susceptibility target gene Target genes the RBD the SARS-CoV-2 therapy TMPRSS2 TMPRSS2 level today transmembrane serine protease transmembrane serine protease 2 Variation virus was determined was done [DOI] 10.1002/jmv.26107 PMC 바로가기 [Article Type] Article
Individuating Possibly Repurposable Drugs and Drug Targets for COVID-19 Treatment Through Hypothesis-Driven Systems Medicine Using CoVexCoVex를 사용한 가설 기반 시스템 의학을 통한 COVID-19 치료를 위한 재사용 가능한 약물 및 약물 표적 개별화Review Published on 2020-11-012022-08-31 Journal: Assay and drug development technologies [Category] 신약개발, 유전자 메커니즘, 치료제, [키워드] Algorithm Analysis anisindione approved drug approved drugs argatroban betrixaban caused coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease Dabigatran dabigatran etexilate death drug drug target drugs drugs targeting effective GGCX GLA host protein host proteins hypotheses in silico initial involved mechanisms Medicine network-based drug repurposing pandemic PLAT platform reveal SARS-CoV-2 SARS-CoV-2 virus starting System systems medicine target targets the SARS-CoV-2 virus Treatment urokinase Vaccine ximelagatran [DOI] 10.1089/adt.2020.1010 PMC 바로가기 [Article Type] Review
Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19코로나바이러스감염증-19(COVID-19) 전 몇 주 동안 최적의 수분 공급이 COVID-19로 인한 사망의 위험 요소라는 가설Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 receptors active transport airway airways aldosterone angiotensin angiotensin converting enzyme AQP5 aquaporin Attention balance body water capillary leakage chronic chronic disease Chronic hydration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 mortality COVID-19 testing drinking water Drinking water intervention Effect endothelial enzyme epidemiological epithelial cells Evidence exaggerated immune response exposure to favor greater growth factor Hydration Hypertonicity hypothese hypotheses Hypovolemia increase Infection intake kinase likelihood limit lung lung epithelial cell Lung epithelial cells Male sex mechanism Mortality Older age pathway Pathways positive public health receptor recommendation reduce reduced risk factor Risk factors risk of COVID-19 risk reduction Saliva osmolality SGK1 Signaling TNF-alpha total body total body water Transport Treatment Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-alpha Vascular vascular endothelial growth factor VEGF VEGF. Via water Water balance [DOI] 10.1016/j.mehy.2020.110237 PMC 바로가기 [Article Type] Article
Life-threatening course in coronavirus disease 2019 (COVID-19): Is there a link to methylenetetrahydrofolic acid reductase (MTHFR) polymorphism and hyperhomocysteinemia?생명을 위협하는 코로나바이러스 질병 2019(COVID-19) 과정: MTHFR(methylenetetrahydrofolic acid reductase) 다형성 및 고호모시스테인혈증과 관련이 있습니까?Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] 유전자 메커니즘, [키워드] carbon coronavirus disease Course COVID-19 COVID-19 pandemic develop disease severity distribution epidemiological data Gender Hyper-homocysteinemia hypothese hypotheses Hypothesis immune Interaction mechanism metabolism MTHFR MTHFR C677T One-carbon metabolism Pathomechanism polymorphism prophylactically resulting reveal risk factor Risk factors severe disease Spread tested [DOI] 10.1016/j.mehy.2020.110234 PMC 바로가기 [Article Type] Article
Childhood Immunization and COVID-19: An Early Narrative ReviewPublic Health Published on 2020-10-282022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] absence Adults age Analysis Anti-viral treatment arising association BCG childhood children clinical investigation COVID-19 COVID-19 pandemic Diseases effective Endemic genomic global public health groups Heterologous hypotheses immune response Immunity immunization immunological infect infected children less MMR narrative outcome protective effect protective role provide reported resulting review Safe SARS-CoV-2 severe symptom severity of symptom the disease the SARS-CoV-2 virus Topic vaccination Vaccine Vaccines virus [DOI] 10.3389/fpubh.2020.587007 PMC 바로가기 [Article Type] Public Health
Understanding Knowledgeable Workers’ Behavior Toward COVID-19 Information Sharing Through WhatsApp in PakistanPsychology Published on 2020-10-072022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] applied Behavior collected data COVID-19 developing country disease form Google help hypotheses individual information information sharing behavior Intention media positive attitude social media Theory of Planned Behavior theory of prosocial behavior theory of use and gratification understanding WhatsApp [DOI] 10.3389/fpsyg.2020.572526 PMC 바로가기 [Article Type] Psychology
Associations between psychiatric disorders, COVID-19 testing probability and COVID-19 testing results: findings from a population-based studyPapers Published on 2020-09-222022-10-27 Journal: BJPsych Open [Category] COVID-19, [키워드] Analysis association Cohort contract the virus COVID-19 COVID-19 complications COVID-19 test COVID-19 testing diagnose diagnoses disorder epidemiological data Epidemiology Fisher exact test hypotheses increased risk individual lack Logistic regression negative test outcome outcome studies outcomes participant patients precluded Probability psychiatric diagnoses psychiatric diagnosis psychiatric disorder Psychiatric disorders psychiatric history psychiatrist receiving Result service users significantly more stigma and discrimination Substance use tested two-sided UK biobank with COVID-19 [DOI] 10.1192/bjo.2020.75 PMC 바로가기 [Article Type] Papers
Can Adenosine Fight COVID-19 Acute Respiratory Distress Syndrome?Review Published on 2020-09-212022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] accompanied acute lung injury acute respiratory distress acute respiratory syndrome adenosine ARDS Can clinical conditions compassionate use coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient CT-scan Cytokine storms Cytokines storm develop epithelial feature hypotheses hypoxia immune system Inflammatory cytokine storm inflammatory process inhibit interstitial pneumonia negativity obesity Patient patients with comorbidities Protein receptors reduce respiratory Respiratory failure SARS-CoV-2 SARS-CoV2 detection syndrome the cytokine storm therapy treated turn [DOI] 10.3390/jcm9093045 PMC 바로가기 [Article Type] Review
The Impact of Risk Perception on Social Distancing during the COVID-19 Pandemic in ChinaArticle Published on 2020-08-272022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] Affect Analysis China Chinese collected conducted COVID-19 COVID-19 pandemic Critical diffusion effective Hierarchical hypotheses Impact implementation IMPROVE Linear regression management management guideline mechanism Perceived Perception Perspective physical distancing positive positive correlation predict public health reduce Research risk Risk perception safety climate SEM significantly social distancing [DOI] 10.3390/ijerph17176256 PMC 바로가기 [Article Type] Article