immunopathology – Page 8 – Communicable Diseases Research

Acute-on-Chronic Liver Failure: Pathophysiological Mechanisms and Management

Review

Published on 2021-11-082023-08-30
Journal: Frontiers in Medicine [Category] E형 간염,

[키워드] Acute-on-chronic liver failure cirrhosis immunopathology Liver transplantation Stem cell therapy
[DOI] 10.3389/fmed.2021.752875 PMC 바로가기 [Article Type] Review

Therapeutic approaches for SARS-CoV-2 infection

SARS-CoV-2 감염에 대한 치료적 접근

Review

Published on 2021-11-012022-09-11
Journal: Methods (San Diego, Calif.) [Category] 신약개발, 치료제,

Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination

Dispatch

Published on 2021-11-012022-10-31
Journal: Emerging Infectious Diseases [Category] COVID-19, MERS, SARS,

Dysregulated Inflammation During Obesity: Driving Disease Severity in Influenza Virus and SARS-CoV-2 Infections

비만 중 조절되지 않는 염증: 인플루엔자 바이러스 및 SARS-CoV-2 감염의 질병 중증도 유발

Review

Published on 2021-10-282022-09-12
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단,

Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19

조직 단백질 분석은 치명적인 covid-19에서 면역 병리학의 메커니즘과 단계를 식별합니다.

Original Research

Published on 2021-10-282022-09-10
Journal: American Journal of Respiratory Cell and Molecular [Category] COVID19(2023년), Fulltext, MERS, SARS, 유전자 메커니즘, 치료기술, 치료제,

[키워드] abundance Activation Analysis Antiviral antiviral responses B-cell Cancer CD8A chemotactic factor Cluster colony stimulating factor component Control tissue coronavirus coronavirus disease correlated COVID-19 CSF-1 DDX58 death Deceased disease stages Donor Evidence Factor fatal COVID-19 Host IL-18 illness duration immunoassay immunopathology Inflammation lung lymphocyte Macrophage macrophages MCP-3 Meta-analysis Monocytes monocytes/macrophage Mortality multiplex occur organ Organ Donors OSM overlap parenchymal pathway Patient phenol plasma Plasma cells postmortem examination postmortem examinations proapoptotic factor proapoptotic factors profiles Protein proteomic proteomics prothrombotic provide provided pulmonary thrombosis quantification RAGE receptor signaling reduce required S100A12 severity spleen Stage subset therapeutic target therapy thrombosis tissue tissues TRIM21 TYMP Unsupervised clustering Viral Viral RNA was obtained were used
[DOI] 10.1165/rcmb.2021-0358OC PMC 바로가기 [Article Type] Original Research

Multicellular spatial model of RNA virus replication and interferon responses reveals factors controlling plaque growth dynamics

Research Article

Published on 2021-10-252022-10-28
Journal: PLoS Computational Biology [Category] COVID-19,

[키워드] acute respiratory syndrome Analysis antiviral response Cell Cell culture coefficients condition coronavirus COVID-19 cultures cytokine cytokine signaling Cytokine storm diffusion drug candidates early stage epithelial evaluated evidenced excessive inflammation exhibit experiment Factor flu form growth H1N1 influenza H3N2 help highlight immune immune response immunopathology IMPROVE in some in vitro include induce Infection inflammatory condition Inflammatory response Influenza inhibit innate immune response interferon interferon response interferon signaling interferons involved JAK/STAT pathway lesion linear local concentration lung lung cell Lung epithelial cells Lung infection Lungs manifestation mechanism molecular multicellular Occurrence pandemic Pandemics parameter pathway performed plaque plaques protective effect public health radial growth Replication respiratory Respiratory disease respiratory infection responsible reveal RNA virus RNA viruses SARS-CoV-2 severe cases severe inflammation severity Signaling signaling molecule Spanish the disease tissue Treatment Trigger type I interferons understanding Variation viral growth Viral load viral replication virus virus-infected cell
[DOI] 10.1371/journal.pcbi.1008874 PMC 바로가기 [Article Type] Research Article

Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19

Article

Published on 2021-10-232022-10-30
Journal: iScience [Category] COVID-19,

SARS-CoV-2 vaccines–induced thrombotic thrombocytopenia: should we consider immuno-hypersensitivity?

Comment

Published on 2021-10-182022-10-29
Journal: Revista de Saúde Pública [Category] COVID-19, MERS, SARS,

Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy

Article

Published on 2021-10-132022-10-30
Journal: Metabolites [Category] COVID-19,

Impaired function and delayed regeneration of dendritic cells in COVID-19

코로나19에서 손상된 수지상 세포의 기능 장애 및 재생 지연

Clinical Trial

Published on 2021-10-062022-09-10
Journal: PLoS Pathogens [Category] MERS, SARS, 바이오마커, 임상,

[키워드] accompanied activated acute illness acute phase adaptive Adaptive immune response adaptive immune responses alteration analyzed antibody antibody-secreting cells antiviral immunity Blood CD14 CD14+ cell CD14+ cells CD163 CD4 CD86 Cell cells circulating classical monocyte classical monocytes Clinical management consequence contribute correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity DCs dendritic cell dendritic cells Depletion disease disease severity downregulation dysregulated dysregulated innate immune response expansion follicular Frequency functional healthy controls helper cells HLADR hospitalized COVID-19 patient Host immune response identify immune responses immunopathology Impaired impairment Increased Inflammatory response Inflammatory responses inhibitory innate immune response long-lasting manifestation Mild modulation monocyte monocyte subsets Monocytes naïve Patient PD-L1 persistent recognize reduced reduction regeneration SARS-COV-2 infection Secondary infection secondary infections severe disease stimulate subpopulation subset susceptibility systemic inflammation T cell T cells T follicular helper cells the disease therapy these cell These cells Trigger upregulation Viral viral infection viral infections
[DOI] 10.1371/journal.ppat.1009742 PMC 바로가기 [Article Type] Clinical Trial