Safety of bedside surgical tracheostomy during COVID-19 pandemic: A retrospective observational studyResearch Article Published on 2020-09-302022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 24 hour admitted to ICU age alteration appear clinical consequences Cohort Complication complications conducted COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient criteria diagnosis of COVID-19 feasible Gas exchange health care workers health-care ICU ICU admission Infection infection and bleeding intensive care Invasive mechanical ventilation involved mechanically ventilated patient MOST Novel coronavirus occurrence of COVID-19 PaO Patient patients performed reported retrospective Safe Safety significantly lower single-center stoma study period surgical the mean tracheostomy was performed [DOI] 10.1371/journal.pone.0240014 PMC 바로가기 [Article Type] Research Article
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series기계적으로 환기되는 COVID-19 환자에게 분무된 인라인 기관내 도르나제 알파 및 알부테롤: 사례 시리즈Short Report Published on 2020-09-292022-08-13 Journal: Molecular Medicine [Category] 임상, [키워드] Administered administration albuterol analyzed ARDS case sery clinical Clinical data clinical trials collected contribute coronavirus COVID-19 COVID-19 patients demographic discharged distal DNA DNase 1 Dornase alfa Dosing Efficacy electronic medical record electronic medical records FIVE fraction hospital in-line nebulizer system mechanically ventilated mechanically ventilated patient mechanically ventilated patients medical records membrane Mortality mucoid sputum mucopurulent secretion Mucopurulent secretions nebulized NET NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps oxygen Oxygen requirement Patient Registered required Result SARS-CoV-2 serum severe COVID-19 single-center sputum Tolerability toxicities Toxicity Trial veno-venous extracorporeal membrane oxygenation ventilated patient Ventilation viscosity VV-ECMO was reduced with COVID-19 [DOI] 10.1186/s10020-020-00215-w PMC 바로가기 [Article Type] Short Report
The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial인공호흡기를 사용하는 COVID-19 환자에서 위약과 비교하여 72시간 동안 1ng/kg/min 용량의 프로스타사이클린(일로프로스트) 주입 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-08-262022-08-13 Journal: Trials [Category] MERS, 임상, [키워드] (Iloprost (normal saline) 1:1 Acute coronary syndrome Adult patient Adult patients age anticipated Biomarker bleeding blinded Blinding block can not Capital Capital Region capture Clinicians comparator concealed conducted Confirmed Confirmed COVID-19 infection Consent coronary syndrome COVID-19 COVID-19 infection COVID-19 patients criteria Day defined Denmark dissemination dose element endothelial endotheliopathy EudraCT exclusion criteria exploratory facilitate FIVE heart failure Hvidovre Hospital hypersensitivity Iloprost intensive care unit intensive care units investigators Local mechanical ventilation mechanically ventilated mechanically ventilated COVID-19 patients mechanically ventilated patient multicenter normal saline number objective outcome parallel group participant Patient patients performed Placebo Pregnancy primary endpoint prostacyclin protocol randomisation randomised Randomized Randomized controlled trial recruitment REDCap Region Sample size sequence statisticians status stratified Study protocol Suspected thrombomodulin total sample size Trial Urine website Withdrawal [DOI] 10.1186/s13063-020-04696-2 PMC 바로가기 [Article Type] Letter
Comparison of two methods to clear the airways of critically ill children and adults with COVID-19 infection: a structured summary of a study protocol for a pilot randomized controlled trialLetter Published on 2020-07-032022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] age airway Alpha anticipated approved assistant benefit Blinding Care carried Chest Chest physiotherapy children Complication coordinating center COVID-19 Critically ill dissemination element expiratory File healthcare worker hypertonic Hypoxemia ICU ICUs independent intensive care intensive care unit intervention arm invasive ventilation management mechanical ventilation mechanically ventilated patient Mortality nasal nasal mask non-inferiority design Non-invasive non-invasive ventilation number objective Oscillation outcome Oxygenation pandemic participant patients with COVID-19 pediatric performed Physiotherapist pilot multicenter positive positive airway pressure Positive end-expiratory pressure positive pressure ventilation Pragmatic Primary outcome protocol provided random Randomized Randomized controlled trial Randomly recruited recruitment reduce Research responsible Sample size sealed Study protocol treatment for COVID-19 ventilator virus vital signs Volume vomiting website with COVID-19 [DOI] 10.1186/s13063-020-04533-6 PMC 바로가기 [Article Type] Letter
Failure of early extubation among cases of coronavirus disease-19 respiratory failure Case report and clinical experience3900 Published on 2020-07-022022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] adopted Antiviral Antiviral treatment Care carried chronic obstructive clinical experience conducted coronavirus disease 19 Coronavirus disease-19 criteria Elderly patient Endotracheal intubation expected extracorporeal membrane oxygenation extubation extubation criteria failure Hospitalization iatrogenic Infection Injury intubation likelihood mechanical ventilation mechanically ventilated patient noninvasive respiratory onset of fever Oxygenation Patient progressed progression Prone position pulmonary disease receive receiving reduce rehabilitation reintubation reported Respiratory failure sputum Strategy Support Supportive treatment symptomatic the disease therapy tracheal transferred Treatment upper respiratory tract Viral pneumonia was performed [DOI] 10.1097/MD.0000000000020843 PMC 바로가기 [Article Type] 3900
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-192022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 1:1 24 hour acute respiratory distress Administered administration Aerogen Aerogen Solo® Aerosols age airway alveolar alveolar injury anticipated ARDS backbone Berlin criteria blinded blocker Breastfeeding carrier cell-free DNA citrullinated histones clearance cleave Clinical practice clinical trial comparator Compound computer-generated consecutive patient control arm coronavirus 2 coronavirus disease COVID-19 COVID-19 patients criteria damage-associated molecular pattern DAMP DAMPs diagnosed with COVID-19 dissemination distal Dornase alfa dose double-stranded DSMB Efficacy element eliminated enteral nutrition Extracellular extracellular DNA fibrosis glycemic control hospital Hospitalized hospitals hyperinflammation hypersensitivity ICU Inclusion inclusion criteria induce Inflammation intensive care interim analysis Intervention Ireland less looser lung lung damage Lungs management mechanical ventilation mechanically ventilated patient monitoring board myeloperoxidase NET NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps number objective Occurrence Open-label outcome PaO Paris participant Patient patients PEEP performed Pneumocytes Primary outcome progression Prone position Protective protocol randomisation randomised randomised controlled trial Randomized receive recruit recruitment reduce reducing Registered respiratory Roche Rothschild Sample size SARS-CoV-2 secretion Sedation Severe COVID-19 pneumonia severe pneumonia severity statistical analysis status study group Study protocol Switzerland syndrome to define Toxicity tracheal Treatment Trial usual care Ventilation vibrating mesh nebulizer Volume website [DOI] 10.1186/s13063-020-04488-8 PMC 바로가기 [Article Type] Letter
High‐dose, short‐term corticosteroids for ARDS caused by COVID ‐19: a case seriesCase Series Published on 2020-06-042022-10-29 Journal: Respirology Case Reports [Category] COVID-19, [키워드] acute respiratory distress Administered administration of corticosteroid Admission ARDS case sery caused Clinical course Clinical management coronavirus disease Corticosteroid corticosteroid therapy COVID COVID‐19 COVID‐19 cytokine early treatment Evidence intravenously Intubated male management mechanical ventilation mechanically ventilated patient median median age Methylprednisolone patients Prevent question Seven syndrome systemic corticosteroid the patient Treatment worsened [DOI] 10.1002/rcr2.596 PMC 바로가기 [Article Type] Case Series
Transport of COVID-19 and other highly contagious patients by helicopter and fixed-wing air ambulance: a narrative review and experience of the Swiss air rescue RegaReview Published on 2020-05-142022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] Coronavirus, MERS, SARS, [키워드] aeromedical Air ambulance ambulance service benefit changed contagious COVID-19 COVID-19 pandemic Europe example HEMS highlight Highly contagious patient Infection prevention Isolation maintain measure mechanically ventilated patient organization Patient patients Personal protective equipment PPE provide the mean the patient Transport transported unique variety [DOI] 10.1186/s13049-020-00734-9 PMC 바로가기 [Article Type] Review