multiorgan failure – Page 8 – Communicable Diseases Research

Prognostic Values of Serum Ferritin and D-Dimer Trajectory in Patients with COVID-19

COVID-19 환자에서 혈청 페리틴 및 D-이량체 궤적의 예후 값

Article

Published on 2021-03-052022-09-10
Journal: Viruses [Category] SARS, 바이오마커,

Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients

중증 COVID-19 환자에서 자가포식 마커의 발현 감소 및 골수 유래 억제 세포의 확장은 불량한 T 세포 반응과 상관관계가 있습니다

Immunology

Published on 2021-02-222022-09-11
Journal: Frontiers in Immunology [Category] MERS, 유전자 메커니즘, 진단,

[키워드] accumulation Activation Affect Analysis analyzed antibody production autophagy B cell B cells CD4+ T cell Cell cellular cellular and humoral immune response coronavirus coronavirus disease Coronavirus Disease (COVID)-19 correlated correlation COVID-19 COVID-19 pathogenesis COVID-19 patient Critical Cytokines dendritic cell dendritic cells diagnostics disease dominant down-regulated driving dysregulated immune response ELISA expansion expression expressions flow-cytometry followed by functional healthy donor HLA-DR humoral immune response iCoS IFN-γ IL-10 IL-6 immune response immunological mechanism implication Inflammation interferon Laboratory parameters lymphocytopenia mild COVID-19 patient mild COVID-19 patients Monocytes multiorgan failure myeloid-derived suppressor cells NKT cells parameter PD-L1 Peripheral blood Pneumonia Poor quantitative PCR Regulatory regulatory lymphocytes respiratory response severe COVID-19 severe COVID-19 patient severe COVID-19 patients Severe patient severe patients significantly subset suppressor suppressor cells susceptible individuals T cell T cell response T cell subset T cells western blot
[DOI] 10.3389/fimmu.2021.614599 PMC 바로가기 [Article Type] Immunology

Membranous nephropathy in a patient with coronavirus disease 2019 (COVID-19): A case report

Case Report

Published on 2021-02-192022-11-01
Journal: Clinical Nephrology. Case Studies [Category] COVID-19,

[키워드] Acute kidney injury Acute kidney injury (AKI) acute tubular necrosis AKI Anemia antibody case sery Chronic kidney disease CKD Coagulation system Collapsing coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 exaggerated immune response Glucose Hispanic Hospitalized hypoxic respiratory failure immune initial Injury kidney dysfunction Membranous nephropathy membranous nephropathy (MN) MOST multiorgan failure nephropathy observation pathological finding Patient Podocytes presenting question raise renal Renal pathology reported SARS-COV-2 infection serum serum creatinine SRAS-CoV-2 target viral particle while with COVID-19 workup
[DOI] 10.5414/CNCS110379 PMC 바로가기 [Article Type] Case Report

[Fatal course of COVID-19 despite IL-6 receptor blockade in cytokine storm : Perimyocarditis and coagulopathy after administration of tocilizumab]

[사이토카인 폭풍에서 IL-6 수용체 차단에도 불구하고 코로나19의 치명적인 경과 : 토실리주맙 투여 후 심근주위염 및 응고병증]

Case Reports

Published on 2021-02-012022-09-11
Journal: Anaesthesist [Category] 진단, 치료제,

[키워드] Administered administration Admission ARDS Azithromycin blockade can not Cardiac arrhythmia circulatory shock Clinical deterioration Coagulopathy Course COVID-19 criteria cytokine Cytokine storm diagnosed died ECMO Efficacy English Exacerbation hemodynamic instability hospital Hydroxychloroquin Hydroxychloroquine IL-6 receptor inflammation marker initiated lAbel male moderate multiorgan failure occurred off-label Patient patient selection Perimyocarditis Pneumonia Randomized controlled studies receptor receptor antagonist respiratory insufficiency second dose Shock Tage the patient Tocilizumab Treatment treatment with tocilizumab with COVID-19 worsened
[DOI] 10.1007/s00101-020-00871-x PMC 바로가기 [Article Type] Case Reports

HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV

SARS-CoV-2 및 MERS-CoV의 고분자 억제제로서의 HTCC

Article

Published on 2021-01-282022-09-11
Journal: Journal of Virology [Category] 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity bats block Care characterization China chitosan chloride circulating Cluster Compound Coronaviridae coronavirus demonstrated Entry epithelia escaped ex vivo model HCoV HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 Health Health care highly pathogenic HKU1 host cell HTCC human airway human airway epithelia human coronavirus humans in vitro infect information inhibited inhibition inhibitor Interaction life-threatening Local measure mechanism mechanism of action member MERS MERS-CoV Middle East Middle East respiratory syndrome Coronavirus multiorgan failure NL63 Novel coronavirus OC43 pandemic pathogen Polymer Rapid Research respiratory respiratory infection respiratory syndrome coronavirus S protein SARS-CoV-2 SARS-COV-2 infection Seven severe acute respiratory syndrome Coronavirus Spread the S protein virus virus entry viruses
[DOI] 10.1128/JVI.01622-20 PMC 바로가기 [Article Type] Article

COVID-19 Induced Bilateral Lower Limb Ischemia and Visceral Infarcts

Cardiac/Thoracic/Vascular Surgery

Published on 2021-01-192022-10-31
Journal: Cureus [Category] COVID-19,

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

COVID-19 및 Toll-Like Receptor 4(TLR4): SARS-CoV-2는 TLR4에 결합하고 활성화하여 ACE2 발현을 증가시켜 진입을 촉진하고 과염증을 유발할 수 있습니다

Review

Published on 2021-01-142022-09-10
Journal: Mediators of Inflammation [Category] 치료제,

[키워드] ACE2 activate Activation alveolar cell antagonist Antiviral appear ARDS bind binding cause causes causing Cell cell surface cells clinical trial contribute COVID-19 COVID-19 patients Cytokines decrease entry receptor Evidence expressed expression Facilitating heart failure hyperinflammation Immune cell immune cells include increase Infection Inflammation Injury innate immune innate immune response interferons lung Lungs Mortality multiorgan failure multiple-organ myocarditis PAMPs pathogen pathogen-associated molecular pattern pathogen-associated molecular patterns Pathogenesis pathogenesis of SARS-CoV-2 pathophysiological Proinflammatory cytokine proinflammatory cytokines promise protein-protein interaction Pulmonary surfactants receptor recognize reported Respiratory failure SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 spike glycoprotein secrete Sepsis severe COVID-19 significantly spike glycoprotein Spike protein surface tension tension the cell the SARS-CoV-2 the spike protein the strongest therapeutic target TLR4 Treatment Trigger triggers type I interferon type I interferons Viral Viral protein Viral proteins
[DOI] 10.1155/2021/8874339 PMC 바로가기 [Article Type] Review

Severe COVID-19 and Sepsis: Immune Pathogenesis and Laboratory Markers

Review

Published on 2021-01-122022-10-29
Journal: Microorganisms [Category] COVID-19,

[키워드] accompanied acute respiratory syndrome changes in chemokine clinical picture Coagulation condition coronavirus country COVID-19 COVID-19 infection COVID-19 pathogenesis Critical cytokine Cytokine storm Cytokines event Factor Host Hypothesis immune response immune responses include Inflammation inflammatory immune response inflammatory reactions involved lung damage management multiorgan failure novel coronavirus disease outbreak outcome pathogenesis of COVID-19 Patient plasma progression Proinflammatory cytokine Quantitative SARS-CoV-2 Sepsis Serum level severe COVID-19 similarity the disease therapy thought Vascular Viral load viral replication virus
[DOI] 10.3390/microorganisms9010159 PMC 바로가기 [Article Type] Review

Genetic Variation, Diet, Inflammation, and the Risk for COVID-19

유전적 변이, 식단, 염증 및 COVID-19의 위험

Editorial

Published on 2021-01-012022-09-11
Journal: Lifestyle genomics [Category] 변종,

[키워드] addition African American African Americans alpha-linolenic acid American anti-inflammatory agents arachidonic acid balance C-reactive protein caused characterized contributing to COVID-19 COVID-19 risk CRP cytokine Cytokine storm Cytokines diet difference disease docosahexaenoic acid Eicosapentaenoic acid elevated EPA European Evolution facilitate Factor FADS1 FADS2 fatigue fatty Fatty acid fatty acids Frequency fructose fruits Genetic variant genetic variants Genetic variation group Haplotype Health hyperinflammation IL-6 immune system Inflammation intake Interaction interleukin interleukin (IL)-1 lead leads less life-threatening linoleic acid low-grade inflammation manifestation Mild modulate multiorgan failure Necrosis obesity Omega omega-3 omega-3 fatty acid Omega-3 fatty acids Omega-6 and omega-3 fatty acid balance. Omega-6 fatty acid omega-6 fatty acids Patient physician Pneumonia Polyunsaturated Population population groups Precision professionals proinflammatory prothrombotic PUFAs SARS-CoV-2 susceptibility susceptible Symptoms therapy thrombotic TNF Trigger Tumor tumor necrosis tumor necrosis factor Variation viral replication
[DOI] 10.1159/000513886 PMC 바로가기 [Article Type] Editorial

COVID-19 patient with coronary thrombosis supported with ECMO and Impella 5.0 ventricular assist device: a case report

Grand Round

Published on 2020-12-202022-10-31
Journal: European Heart Journal: Case Reports [Category] COVID-19,