other organs
[용어속성] Organ
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Research
[키워드] ACE2
activated T cells
acute respiratory syndrome
animal model
can be used
cause
coronavirus
driven by
enzyme
evaluate
evaluated
expressing
feature
Hospitalized
Human
immune
impaired function
Infection
infiltration
innate immune response
interferon signaling
K18
K18-hACE2
K18-hACE2 mice
leukocyte activation
Lung disease
lung tissue
Lungs
mice
Monocytes
neutrophil
nuclear
occur
other organs
Pathways
phenotype
promoter
Pulmonary function
receptor
SARS-CoV-2
SARS-COV-2 infection
Severe COVID-19 Infection
severe lung inflammation
spread to
to define
transgenic mice
type I
upregulated
viral infection
viral titer
[DOI] 10.1038/s41590-020-0778-2 [Article Type] Research
[DOI] 10.1038/s41590-020-0778-2 [Article Type] Research
Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients
Research
[키워드] absence
Artery
Atypical
Autopsy
Brain
case sery
change
Colon
COVID-19
COVID-19 patient
COVID-19 patients
DAD
Diffuse alveolar damage
disease
distribution
Encephalitis
evaluated
Evidence
feature
Hepatitis
heterogeneity
heterogeneous
IHC
immunohistochemistry
information
kidney
lesion
lesions
liver
lung
macroscopic
microthrombi
Multiorgan
Myocardial
myocarditis
Non-survivors
organ
organ injury
organs
other organs
Patient
patients
performed
Pneumocytes
Pneumonia
polymerase chain
positive cell
Post-mortem
Presence
pulmonary
reported
Result
RT-PCR
SARS-CoV-2
spleen
spongiosis
tested
tissues
vascular congestion
viral presence
viral spread
virus
[DOI] 10.1186/s13054-020-03218-5 PMC 바로가기 [Article Type] Research
[DOI] 10.1186/s13054-020-03218-5 PMC 바로가기 [Article Type] Research
Modeling Potential Autophagy Pathways in COVID-19 and Sarcoidosis
Mini review
[키워드] acute respiratory syndrome
Affect
autoinflammatory disease
autophagy
caused
cellular pathway
characterized
coronavirus
Coronavirus disease 2019
COVID-19
diffusion
disease
granuloma
lung
Lungs
modeling
other organs
Potential
Regulation
SARS-CoV-2
[DOI] 10.1016/j.it.2020.08.001 [Article Type] Mini review
[DOI] 10.1016/j.it.2020.08.001 [Article Type] Mini review
Liver Injury in COVID-19 Infection: A Systematic Review
Internal Medicine
[키워드] acute respiratory syndrome
appear
article
articles
authors
case-control study
conducted
Confirmed COVID-19 infection
coronavirus
Course
COVID-19
COVID-19 patient
COVID-19 patients
cross-sectional study
death
determine
elevated liver associated enzymes
eligibility criteria
eligible
Evidence
Final
FIVE
heterogeneity
independent
Infection
initial
Injury
lft - liver function tests
library
limitation
liver
Liver damage
liver enzyme
liver enzymes
Liver injury
liver test
manual
Medicine
Medline database
Mild
Mortality
novel coronavirus disease
other organs
outcome
pandemic
pathology
Patient
Prevalence
produced
progression
reported
review
SARS-CoV-2
screened
searched
severity of COVID-19
systematic review
the disease
the patient
trajectory
was done
with COVID-19
[DOI] 10.7759/cureus.9487 PMC 바로가기 [Article Type] Internal Medicine
[DOI] 10.7759/cureus.9487 PMC 바로가기 [Article Type] Internal Medicine
Clinical characteristics of 82 cases of death from COVID-19
코로나19 사망자 82명의 임상적 특징
Research Article
[키워드] Admission
age
Alanine
alanine aminotransferase
aspartate
Aspartate aminotransferase
association
C-reactive protein
Cancer
cardiac failure
cause of death
caused
Cerebrovascular disease
Characteristics
clinical
Clinical characteristics
Clinical data
Comorbidities
Comorbidity
COVID-19
cytokine
cytokine release
Cytokine release syndrome
D-dimer
Data collection
death
death case
detected patients
develop
diabete
diabetes
diagnosed
died
disease
electronic medical record
followed by
forms
heart disease
hemorrhage
Hemorrhagic
hemorrhagic damage
hypertension
ICU
IL-6
initial symptom
initial symptoms
IQR
laboratory-confirmed
Lactate
lactate dehydrogenase
Local
lymphocyte
lymphopenia
male
mechanical ventilation support
median age
median time
medical records
MOST
Most patient
Most patients
neutrophil
Neutrophil-to-lymphocyte ratio
neutrophilia
Older
on admission
other organs
oxygen
Patient
patients
Pneumonia
proportion
remained
renal
renal damage
renal failure
respiratory
Respiratory failure
SARS-CoV-2
SARS-COV-2 infection
Sepsis
severe disease
single center
Spread
systemic immune-inflammation index
the median
the patient
thrombocytopenia
treated
virus
Wuhan
Wuhan local hospital’
Wuhan, China
[DOI] 10.1371/journal.pone.0235458 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pone.0235458 PMC 바로가기 [Article Type] Research Article
The Lung Macrophage in SARS-CoV-2 Infection: A Friend or a Foe?
Immunology
[키워드] ACE-2
ACE2
acute respiratory distress syndrome
adverse effect
affected
Ang II
angiotensin
angiotensin-converting enzyme 2
Antiviral
binding
Cell
COVID-19
Defense
dendritic cells
Effects
expressed
expressing
expression
feature
fibrosis
Friend
glycoprotein
high mortality rate
homing
host cells
Hypothesis
immune system
individual
Inflammation
lung
Macrophage
macrophages
mechanisms
organ
organ injury
organ-specific
other organs
other tissue
protease
pulmonary parenchyma
receptor
renal
Replication
reservoir
respiratory
responsible
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV2
severity
subsequent
tissue
Vascular
viral spike
viral spread
[DOI] 10.3389/fimmu.2020.01312 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01312 PMC 바로가기 [Article Type] Immunology
Acute respiratory failure in COVID-19: is it “typical” ARDS?
Review
[키워드] acute respiratory distress
acute respiratory distress syndrome
Acute respiratory failure
affected
alveolar epithelial cell
ARDS
ARDS patient
ARDS patients
Berlin criteria
caused
Characteristics
clinical manifestation
Comorbidity
coronavirus
coronavirus disease
Corticosteroid
COVID-19
COVID-19 patients
damaged
death
defined
Effect
Endothelial cell
Factors
Health
help
HFNO
IMPROVE
International
Invasive mechanical ventilation
Laboratory
less
limit
Mild
moderate-severe
Mortality
normal lung compliance
other organs
outbreak
Patient
patients
Prognosis
reduce
Respiratory system
Safe
Severe case
severe respiratory failure
severity
Stage
syndrome
the timing
Treatment
WHO
World Health Organization
Wuhan, China
[DOI] 10.1186/s13054-020-02911-9 PMC 바로가기 [Article Type] Review
[DOI] 10.1186/s13054-020-02911-9 PMC 바로가기 [Article Type] Review
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
수용체 ACE2 발현에 대한 단일 세포 RNA-seq 데이터 분석은 2019-nCoV 감염에 취약한 다양한 인간 장기의 잠재적 위험을 보여줍니다
Research Article
[키워드] 2019-nCoV
2019-nCoV infection
ACE2
ACE2 expression
alveolar cell
analyses
Analysis
analyzed
angiotensin
angiotensin converting enzyme
AT2
bladder
cell type
cell types
cells
China
dataset
digestive
enzyme II
epithelial cells
esophagus
expression
heart
human cell
human cells
ileum
kidney
Kidney failure
lung
lung cell
lung cells
material
Myocardial
nCoV
Novel coronavirus
organ
organs
other organs
Pathogenesis
Patient
physiological systems
potential risk
proximal tubule
proximal tubule cell
proximal tubule cells
receptor
receptor ACE2
respiratory
reveal
risk
RNA-seq data
route
SARS-CoV
scRNA-seq
scRNA-seq data
Single-cell RNA sequencing
single-cell RNA-seq
Symptoms
target cell
target cells
vulnerability
Wuhan
[DOI] 10.1007/s11684-020-0754-0 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1007/s11684-020-0754-0 PMC 바로가기 [Article Type] Research Article
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes
2019-nCoV 감염 환자의 분자 및 혈청학적 조사: 다중 배출 경로의 의미
Article
Published on
Journal: Emerging Microbes & Infections [Category] Communicable Disease, COVID-19, MERS, SARS,
Journal: Emerging Microbes & Infections [Category] Communicable Disease, COVID-19, MERS, SARS,
[키워드] 2019-nCoV
2019-nCoV infected patient
2019-nCoV infected patients
anal swab
anal swabs
Blood
caused
conducted
confirmation
coronavirus
disease
Epidemiology
hospital
IMPROVE
infecting
Infection
intestine
intestines
Local
Molecular diagnosis
nCoV
Novel coronavirus
oral swab
oral swabs
other organ
other organs
outbreak
Patient
Pneumonia
positive
positive rate
provide
released
respiratory
respiratory tract
serological
serology test
shedding
spread to
swabs
tested
transmitted
virus
was used
were infected
Wuhan
Wuhan pneumonia
Wuhan, China
[DOI] 10.1080/22221751.2020.1729071 PMC 바로가기 [Article Type] Article
[DOI] 10.1080/22221751.2020.1729071 PMC 바로가기 [Article Type] Article