From Standard to Escalated Anticoagulant Prophylaxis in Fractured Older Adults With SARS-CoV-2 Undergoing Accelerated Orthopedic SurgeryMedicine Published on 2020-10-152022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Anticoagulant Anticoagulants Antithrombotic bases cardiovascular complication complications COVID-19 COVID-19 drug treatment daily dose death deaths dosage doubling Efficacy faster femoral fractures High dose high risk highest hospital incidence increased survival infected patient Injury Italian Italy knowledge lombardy Low-molecular-weight heparin mandatory metabolic derangement nine Older orthopedic pandemic pathophysiology Patient patients pharmacological treatment Prevalence Prophylaxis protocol reduction in SARS-CoV-2 SARS-COV-2 infection Seven Spread Standard statistically significant subsequent surgeon surgery surgical Symptom the disease trauma treated Treatment virus [DOI] 10.3389/fmed.2020.566770 PMC 바로가기 [Article Type] Medicine
COVID-19: A Therapeutic Approach Based on Pathophysiological StagingRespiratory Medicine Published on 2020-10-132022-10-28 Journal: The Open Respiratory Medicine Journal [Category] COVID-19, [키워드] caused Characteristics conditioned Confusion contributed COVID-19 pandemic creating Cytokine storm disease distress event Evidence include knowledge lack limitation Other pathophysiology pharmacological pharmacological treatment Respiratory failure staging syndrome the disease therapeutic Therapeutic approach therapeutic decision treated Treatment viral replication [DOI] 10.2174/1874306402014010032 PMC 바로가기 [Article Type] Respiratory Medicine
Use of Tocilizumab in COVID-19: A Systematic Review and Meta-Analysis of Current EvidenceInternal Medicine Published on 2020-10-092022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 95% confidence interval Abstract analyses Analysis anti-IL-6 article articles baseline characteristics biologic agent calculated case-control study collaboration college control arm control group coronavirus disease COVID-19 COVID-19 patients Critical Critically ill current database demonstrated Denmark Efficacy elevated Endpoint Health IL-6 Immunological response Infection intensive care interleukin-6 invasive ventilation material mean difference Meta-analysis Mortality observational studies outcome oxygen saturation Patient patients with COVID-19 pharmacological treatment positive random effect model reducing mortality regimen reported Result review risk risk ratio Safe Safety SARS-CoV-2 searched Seven severe COVID-19 significant difference significantly lower standard care group Stata Corporation Station suggested systematic review Tocilizumab tocilizumab patient treatment with tocilizumab were used [DOI] 10.7759/cureus.10869 PMC 바로가기 [Article Type] Internal Medicine
Safety and effectiveness of azithromycin in patients with COVID-19: An open-label randomised trialRandomized Controlled Trial Published on 2020-10-012022-10-06 Journal: International journal of antimicrobial agents [Category] SARS, 진단, [키워드] addition Admission arrythmia Azithromycin Cardiac arrhythmia cardiac disease Cardiology college Combination conducted control group coronavirus disease COVID-19 criteria discharge duration of hospitalisation Effectiveness Follow-up general condition HCQ Hydroxychloroquine individual Initially intensive care Iran laboratory-confirmed Lopinavir main outcome measure mortality rate no significant difference Open-label Patient pharmacological treatment randomised controlled trial Randomised trial receiving regimen respiratory rate risk Ritonavir Safety SARS-CoV-2 significantly higher two groups vital sign vital signs were assessed were excluded [DOI] 10.1016/j.ijantimicag.2020.106143 PMC 바로가기 [Article Type] Randomized Controlled Trial
Low dose anti-inflammatory radiotherapy for the treatment of pneumonia by covid-19: A proposal for a multi-centric prospective trialResearch article Published on 2020-09-012022-10-05 Journal: Clinical and Translational Radiation Oncology [Category] 치료법, [키워드] adhesion molecules Anti-inflammatory anti-inflammatory cytokine anti-inflammatory effect caused contagious control arm control group COVID COVID-19 cytokine release dose Efficacy Efficiency evaluate evaluated experimental arm exploratory expression feasibility Health include increase in Inflammatory inflammatory cascade interfere interstitial pneumonia low-dose lung mechanism morbidity Non-invasive overall mortality oxidative stress paO2/fiO2 PaO2/FiO2 ratio patients patients with COVID-19 pharmacological treatment Pneumonia primary end-point Prospective clinical trial Prospective Study Prospective trial radiation therapy Radiotherapy receive reducing resources respiratory complication Respiratory function Secondary objective severity the patient therapy Treatment viral infection [DOI] 10.1016/j.ctro.2020.06.005 [Article Type] Research article
Impact of COVID-19 on Alzheimer’s Disease Risk: Viewpoint for Research ActionPerspective Published on 2020-08-212022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] ACE2 Action age Alzheimer’s disease Alzheimer’s disease risk analyzed Consequences coronavirus 2 coronavirus disease COVID-19 Dementia disease Diseases effort Impact mechanism medical condition neurodegenerative Neuroinvasive neuroinvasivness outbreak pharmacological treatment positive raise respiratory risk SARS-CoV-2 SARS-CoV-2 infected subjects SARS-COV-2 infection Scientific community severe symptom subjects Vaccine virus infection [DOI] 10.3390/healthcare8030286 PMC 바로가기 [Article Type] Perspective
Second Update for Anaesthetists on Clinical Features of COVID-19 Patients and Relevant ManagementReview Published on 2020-08-062022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] angiotensin converting enzyme 2 Antiviral agents clinical COVID-19 COVID-19 pandemic COVID-19 patient diabetic patients diagnostics Evidence healthcare worker Laboratory nervous system Operating room patient-to-professional infectious disease transmission Perioperative care pharmacological treatment presenting provided risk risk of transmission SARS-CoV-2 second Topic [DOI] 10.3390/jcm9082542 PMC 바로가기 [Article Type] Review
Mesenchymal stem cells: current clinical progress in ARDS and COVID-19Review Published on 2020-07-222022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, SARS, [키워드] acute respiratory distress syndrome animal model ARDS Cell Cell therapy clinical implication Clinical management clinical trials coronavirus disease COVID-19 current develop distress Factors fluid input high mortality rate Lung diseases Mesenchymal stem cells Mesenchymal stromal cell MSC MSCs pandemic pharmacological treatment protective effect Quality of life reported Respiratory Support shown suggested syndrome therapy Treatment [DOI] 10.1186/s13287-020-01804-6 PMC 바로가기 [Article Type] Review
Spontaneous Pneumomediastinum Associated With SARS-CoV-2: Infrequent Complication of the Novel DiseaseRadiology Published on 2020-07-142022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress Acute respiratory infection acute respiratory syndrome biochemical chest infection chronic lung diseases Comorbidity Complication complications coronavirus develop diagnosed Diagnosis distribution emphysema fatigue global pandemic ground-glass opacity had no Health highlight Hospitalization Infection Infrequent Intensive Laboratory results male management medical condition myalgia nausea noninvasive novel Novel coronavirus oxygen supply pandemic Patient pharmacological treatment Pneumomediastinum Pneumonia radiological SARS-CoV-2 SARS-CoV2 Shortness of breath significantly smoking Spontaneous subsequent Symptom syndrome the disease the patient Treatment [DOI] 10.7759/cureus.9189 PMC 바로가기 [Article Type] Radiology
Complement Inhibition in Coronavirus Disease (COVID)-19: A Neglected Therapeutic OptionImmunology Published on 2020-07-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] complement inhibition coronavirus COVID-19 hyperinflammation inhibition Innate immunity Neglected option pharmacological treatment [DOI] 10.3389/fimmu.2020.01661 PMC 바로가기 [Article Type] Immunology