Comparison of Severe Maternal Morbidities Associated With Delivery During Periods of Circulation of Specific SARS-CoV-2 Variants특정 SARS-CoV-2 변이체의 순환 기간 동안 분만과 관련된 심각한 산모 이환율의 비교Multicenter Study Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] age Alpha Alpha variant amplification analyzed association B.1.1.7 B.1.617.2 cause center characterized clinical variable cohort study complications Control COVID-19 defined delivery Delta delta variant demographic and clinical variables disease control dominant evaluate event events Evidence evidence of example health system highest Hospitalization individual Infection IQR Maternal median morbidity multicenter nucleic acid nucleic acid amplification test Odds ratio omicron outcome outcomes over pandemic Patient patients with SARS-CoV-2 Period predominant pregnant patient pregnant patients prevention preventive measures Primary outcome reflected Respiratory complications retrospective cohort study risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleic acid secondary Secondary outcomes severity of COVID-19 significantly higher Specific Strains test result the SARS-CoV-2 type strain Variation viral strain viral strains was increased while wild-type strain [DOI] 10.1001/jamanetworkopen.2022.26436 PMC 바로가기 [Article Type] Multicenter Study
Experience with open schools and preschools in periods of high community transmission of COVID-19 in Norway during the academic year of 2020/20212020/2021 학년도 동안 노르웨이에서 COVID-19의 높은 지역사회 전파 기간 동안 개방 학교 및 유치원 경험Article Published on 2022-07-302022-09-11 Journal: BMC Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] adherence adolescents Alpha variant children Community community transmission country COVID-19 COVID-19 case COVID-19 cases defined Educational settings evaluate experience flexible incidence of COVID-19 incidence rate Infection prevention initiated Local measure media median MOST National Norway occurred on children outbreak Outbreaks pandemic predominant Preschool Preschools prevention primary school Public public health pupil Pupils reduce remained reported SARS-CoV 2 School Schools secondary school setting Surveillance with infection [DOI] 10.1186/s12889-022-13868-5 PMC 바로가기 [Article Type] Article
Neurovascular injury with complement activation and inflammation in COVID-19COVID-19에서 보체 활성화 및 염증으로 인한 신경 혈관 손상Article Published on 2022-07-292022-09-12 Journal: Brain : a journal of neurology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] accompanied Activation acute respiratory syndrome adherent aggregate aggregation Analysis astrogliosis autopsy study B cell Brain CD4+ T cell CD8+ T cells cellular change changes in characterized classical complement complement deposition Complement pathway complexes coronavirus coronavirus disease COVID-19 cytotoxicity determine died Endothelial cell First wave hindbrain humoral immune response immune complex immunohistochemistry Infection Inflammation Injury Macrophage mechanism microthrombi Neuroinflammation neurological manifestation neuronal Neurovascular neurovascular injury. nodule pandemic pathological change pathology pathophysiological mechanisms Patient patients died performed perivascular Platelet Platelets Post-mortem predominant Quantitative regions SARS-CoV-2 Serum protein short duration Vascular Vascular damage vascular leakage widespread [DOI] 10.1093/brain/awac151 PMC 바로가기 [Article Type] Article
Case report: Variant-specific pre-exposure prophylaxis of SARS-CoV-2 infection in multiple sclerosis patients lacking vaccination responses증례 보고: 백신 접종 반응이 없는 다발성 경화증 환자에서 SARS-CoV-2 감염의 변종 특이적 노출 전 예방Case Reports Published on 2022-07-252022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-CD20 treatment antibody cocktail approved Asymptomatic Case report Case series case sery Casirivimab cilgavimab conducted coronavirus coronavirus disease coronavirus disease (COVID-19) COVID-19 infection develop dose European Evidence evidence of FIVE humoral Imdevimab immunomodulatory Immunotherapy impair incidence Infection Initially monoclonal monoclonal antibody multiple sclerosis Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody offered omicron Omicron variant one patient pandemic Patient patients positive RT-PCR predominant prophylactic treatment Prophylaxis receptor reduced respiratory respiratory tract infection response retained Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2-neutralizing antibodies SARS-CoV-2-neutralizing antibody SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe adverse event severe adverse events Sotrovimab specific antibodies sphingosine sphingosine-1-phosphate sphingosine-1-receptor modulators (S1PR) sustained Symptom T-cell T-cells the patient the SARS-CoV-2 Tixagevimab Treatment union upper respiratory tract upper respiratory tract infection vaccination vaccination response variant were recorded [DOI] 10.3389/fimmu.2022.897748 PMC 바로가기 [Article Type] Case Reports
SARS-CoV-2 Seroprevalence among Healthcare Workers after the First and Second Pandemic Waves1차 및 2차 대유행 이후 의료 종사자 사이의 SARS-CoV-2 혈청 유병률Article Published on 2022-07-142022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibody antibodies Belgium Blood Charleroi confirmed COVID-19 case Contact COVID-19 criteria cross-sectional diagnostic DiaSorin distribution First wave General population HCW HCWs healthcare healthcare worker Healthcare workers hospital IgG test Inpatients LIAISON pandemic pandemic waves Patient patients performed positive predominant Prevalence questionnaire recruitment repeated risk risk factor S1/S2 SARS-CoV-2 second second wave Seroconversion serological test Serological testing Seroprevalence significantly higher single-center study participant Symptom treated Wave worker [DOI] 10.3390/v14071535 PMC 바로가기 [Article Type] Article
Cross-variant protection against SARS-CoV-2 infection in hamsters immunized with monovalent and bivalent inactivated vaccines1가 및 2가 비활성화 백신으로 면역된 햄스터에서 SARS-CoV-2 감염에 대한 교차 변이 보호Article Published on 2022-07-132022-09-11 Journal: International Journal of Biological Sciences [Category] COVID19(2023년), SARS, 변종, [키워드] addition Alpha Alpha variant B.1.1.529 B.1.1.7 B.1.617.2 circulation COVID-19 Delta delta variant determine emergence exhibited experiment form hamster hamsters highest immune evasion immune protection immunized Inactivated vaccine Inactivated Vaccines less monovalent Neutralizing antibodies omicron Omicron variant Omicron variants pandemic of COVID-19 predominant provided Rapid SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 variants of concern SARS-CoV-2 Wuhan strain Support tested Vaccine Vaccine design variant variants VoC VOCs were used [DOI] 10.7150/ijbs.72109 PMC 바로가기 [Article Type] Article
Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats임신한 쥐에서 항바이러스성 렘데시비르와 주요 대사산물인 GS-441524의 생체변환 및 태반 전이Article Published on 2022-07-012022-09-11 Journal: EBioMedicine [Category] 치료제, [키워드] amniotic Amniotic fluid Anti-viral approved AUC Biotransformation Blood Blood-placental barrier C max coronavirus disease Coronavirus disease 2019 COVID-19 cross during pregnancy evaluated fetus GS-441524 Hypothesis Liquid chromatography mass spectrometry maternal blood metabolite Microdialysis MONITOR mother multisite nucleoside parameter pharmacokinetic pharmacokinetics Placenta placental barrier predominant Pregnancy pregnant RATs Remdesivir Science shown Taiwan Tandem mass spectrometry technology tissues transfer treat Treatment UHPLC was used while [DOI] 10.1016/j.ebiom.2022.104095 PMC 바로가기 [Article Type] Article
Evaluation of long-term stability of SARS-CoV-2 nucleic acid extracted from human nasopharyngeal samples인간 비인두 샘플에서 추출한 SARS-CoV-2 핵산의 장기 안정성 평가Article Published on 2022-07-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition analyzed changes checked coronavirus Ct value cut-off detect first test Genes human RP identify Laboratory maintenance media must N1 and N2 nasopharyngeal sample nasopharyngeal specimen New coronavirus predominant protocols Quality-assurance Randomly researchers respond RNA RNA sample RNA samples RT-PCR assay RT-qPCR SARS-CoV-2 gene SARS-CoV-2 genes SARS-CoV-2 nucleic acid significant increase stability subsequent viability virus [DOI] 10.1016/j.jviromet.2022.114529 PMC 바로가기 [Article Type] Article
Detection of the Omicron variant of SARS-CoV-2 in international travelers returning to Venezuela베네수엘라로 귀국하는 해외 여행자에서 SARS-CoV-2의 오미크론 변종 검출Article Published on 2022-07-012022-09-11 Journal: Travel medicine and infectious disease [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis analyzed concern country COVID-19 Delta detect detection exhibited fragment of Frequency Genome genomic region Genomic surveillance increase in International International travels Lineage molecular Mutation mutations nucleic acid omicron Omicron variant Omicron variant of concern positive predominant SARS-CoV-2 SARS-CoV-2 variant Sequencing South Africa the SARS-CoV-2 the Spike variant variant of SARS-CoV-2 variants variants of SARS-CoV-2 Venezuela VoC [DOI] 10.1016/j.tmaid.2022.102326 PMC 바로가기 [Article Type] Article
First cases of infection with the 21L/BA.2 Omicron variant in Marseille, France프랑스 마르세유에서 21L/BA.2 오미크론 변종 첫 감염 사례Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] Amino acid amino acid substitution amino acid substitutions Clinical outcome Cluster country deletions Denmark deviation diagnosed distribution emergence England facilitate flattening France Genome genomes incidence Infection initial Interaction Marseille MONITOR N-terminal domain Nepal Next-generation sequencing nucleotide nucleotide substitution nucleotide substitutions omicron Omicron variant Phylogeny predominant qPCR remained resulting SARS-CoV-2 Singapore South Africa southern France Spike protein Surveillance the spike protein Travel variant viral genome viral genomes [DOI] 10.1002/jmv.27695 PMC 바로가기 [Article Type] Article