pulmonary involvement – Page 8 – Communicable Diseases Research

Tracking the time course of pathological patterns of lung injury in severe COVID-19

Research

Published on 2021-01-292022-10-28
Journal: Respiratory Research [Category] COVID-19,

Short-term cardiac outcome in survivors of COVID-19: a systematic study after hospital discharge

COVID-19 생존자의 단기 심장 예후: 퇴원 후 체계적인 연구

Observational Study

Published on 2021-01-222022-09-11
Journal: Clinical Research in Cardiology [Category] 임상, 치료기술,

[키워드] 105 patient 105 patients Abnormalities abnormality Abstract cardiac caused collected controls COVID-19 COVID-19 patient COVID-19 patients cross-sectional cross-sectional study Diastolic function ECG echocardiography examined Follow-up follow-up visits functional greater heart hospital discharge Hospitalized Infection limitation lung Lung ultrasound matched controls median Mild-to-moderate morbidity and mortality no significant differences objective outcome Patient patients patients who survived pulmonary involvement recruited reported Result severity severity of illness significant difference significantly supplementary material survivor Systolic function Tissue-Doppler imaging ventricular with COVID-19
[DOI] 10.1007/s00392-020-01800-z PMC 바로가기 [Article Type] Observational Study

Evaluation of the efficacy and safety of inhaled magnesium sulphate in combination with standard treatment in patients with moderate or severe COVID-19: A structured summary of a study protocol for a randomised controlled trial

중등도 또는 중증 COVID-19 환자에 대한 표준 치료와 함께 흡입 황산마그네슘의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-01-182022-09-10
Journal: Trials [Category] 임상,

[키워드] 1:1 acute severe asthma adjuvant therapy Administered Affect airway smooth muscle alveolar Anti-inflammatory anticipated Arm ARMS arterial blood arterial blood oxygen saturation arterial oxygen saturation arteriole Artery Asthma attack basic Blinding block Block randomisation blocks blood oxygen Blood oxygen saturation bradyarrhythmia calcium calcium antagonist cardiovascular disease cardiovascular diseases Chest computed tomography Chest CT chest CT scan clinical clinical impact clinical manifestation clinical manifestations Clinical studies clinical study clinical trials Combination Computed tomography Computer software Confirmed congestive heart failure Control Controlled trial cough COVID-19 criteria defined diagnosis of SARS-CoV-2 dissemination Dyspnoea Effect Effects Efficacy and safety eight element eligible patient Eligible patients excluded FIVE functional heart block hospital Hospital stay Hospitalized hospitalized patient hospitalized patients Hypoxemia hypoxia impairment IMPROVE improvement inclusion criteria induce Infection inhalation Inhaled Intervention intervention arm intravenous intravenously Length Lung injury lung involvement magnesium sulphate Mask moderate myocardial injury nasopharyngeal secretion National nebulized number objective Open-label outcome oxygen oxygen saturation Parallel Arm parenchyma participant Patient patients with moderate PCR performed polymerase chain polymerase chain reaction protocol pulmonary artery pulmonary involvement randomisation randomised randomised controlled trial randomization Randomly randomly divided RCT receive reduce Registered registration number registry respiratory respiratory airway respiratory airways Respiratory function respiratory tract respiratory tract symptoms Sample size SARS-COV-2 infection saturation severe COVID-19 Shortness of breath shown smooth muscle relaxant standard treatment status Study protocol supplementary material Symptom Tehran therapy Trial Trial registration Ventilation Version website with COVID-19 Yazd
[DOI] 10.1186/s13063-021-05032-y PMC 바로가기 [Article Type] Letter

Determinants of mortality in a large group of hemodialysis patients hospitalized for COVID-19

Observational Study

Published on 2021-01-142022-10-04
Journal: BMC Nephrology [Category] MERS, 임상,

[키워드] Admission age albumin level Analysis analyzed Aspartate aminotransferase AST Characteristics chronic obstructive Clinical findings Clinical severity clinics collected data congestive heart failure coronavirus disease COVID-19 COVID-19 treatment Cox regression decrease determinant Diagnosis died discharged patients disease ferritin ferritin level had more heart failure Hemodialysis high mortality rate Hospitalization ICU in-hospital mortality increase in increased risk intensive care Laboratory lymphocyte Maintenance hemodialysis manifestation mechanical ventilation median median age Mortality mortality risk Most patient multicenter Older outcome Patient patients patients died patients hospitalized patients with COVID-19 Platelet predict pulmonary disease pulmonary involvement radiologic radiological Radiological manifestations Result retrospective risk factor survival the disease Turkey were recorded with COVID-19
[DOI] 10.1186/s12882-021-02233-0 PMC 바로가기 [Article Type] Observational Study

Correlation between age, sex, and severity of Coronavirus disease-19 based on chest computed tomography severity scoring system

Research

Published on 2021-01-132022-10-31
Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19,

A novel deep learning-based quantification of serial chest computed tomography in Coronavirus Disease 2019 (COVID-19)

코로나바이러스 질병 2019(COVID-19)에서 직렬 흉부 컴퓨터 단층 촬영의 새로운 딥 러닝 기반 정량화

Article

Published on 2021-01-112022-09-01
Journal: Scientific Reports [Category] 진단,

COVID-19-Induced Ischemic Infarcts With Normal Coagulation Profile and Excellent Outcome: A Case Report With Highlights on the Thrombotic Diathesis, Recent Transcranial Doppler Findings, and Neuropathology Update

Neurology

Published on 2021-01-062022-10-31
Journal: Cureus [Category] COVID-19,

Protective reactive thymus hyperplasia in COVID-19 acute respiratory distress syndrome

Observational Study

Published on 2021-01-042022-10-04
Journal: Critical Care [Category] 임상,

[키워드] acute respiratory distress age appear chest CT scan co-morbidities Coagulopathy Concentration contribute Control control group controls correlated COVID COVID patient Covid patients COVID-19 CRP CT scan CT scans develop Factor forms ICU IL-7 initial investigated lack lower mortality Lung injury lung involvement lymphocyte Mortality nasal Older Other Patient PCR performed Plasma cytokine polymerase chain pulmonary involvement quantification reactive Result SARS-CoV-2 SARS-CoV-2 infected patient scored Sepsis syndrome T cell T cell receptor T lymphocyte thymic thymus Thymus reactivation TREC visceral were measured while with COVID-19 worse prognosis
[DOI] 10.1186/s13054-020-03440-1 PMC 바로가기 [Article Type] Observational Study

Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: A structured summary of a study protocol for a randomized, parallel-group, open-label, multi-center pilot trial (PROTECT-COVID-19)

입원한 COVID-19 환자의 중증 SARS-CoV-2 감염 예방을 위한 재조합 인간 C1 에스테라제 억제제(conestat alfa): 무작위, 병렬 그룹, 공개 라벨, 다중 센터에 대한 연구 프로토콜의 구조화된 요약 파일럿 시험(PROTECT-COVID-19)

Letter

Published on 2021-01-042022-09-10
Journal: Trials [Category] 임상,

[키워드] 24 hour 24 hours Activation activities acute lung injury addition adjusted Administered administration allergy Antibiotics anticipated anticoagulation arterial Arterial hypertension Basel Blinding BMI Brazil Breast Breast feeding breathing ambient air C-reactive protein C1 esterase inhibitor cardiovascular disease Caregivers changes in Chest Child-Pugh score chronic chronic pulmonary disease chronic renal disease cirrhosis class clinical Clinical improvement clinical trial comparator comparator Patients complement complement system completion conducted Conestat alfa Contact contact activation system contraindication control group Corticosteroids COVID-19 COVID-19 patient CT scan death defined discharge disease disease severity dissemination drug Duration Efficacy and safety element eligibility enrolment evidence of experimental arm family members FIVE followed by history hospital Hospitalization hospitalized patient hypertension ICU IL-6 inhibitor IL-6R improvement Incapacity include inclusion criteria individual Infection inflammatory cascade inflammatory cascades inflammatory proteins inhibitor Interactive Web Response System interim analysis Intravenous injection invasive invasive or non-invasive ventilation investigator-initiated investigators kallikrein kinin system laboratory parameter Liver cirrhosis Local Lung injury mechanical ventilation non-invasive ventilation not blinded number obesity objective Open-label open-label trial Ordinal Scale outcome outcome assessor outcome assessors oxygen oxygen saturation pandemic PaO parallel-group participant Participants Participation Patient performed Pregnancy primary endpoint progression proportion protocol pulmonary disease pulmonary involvement randomised randomization Randomized randomized trial receive recombinant recruited recruitment Registered Remdesivir renal renal disease required risk factor Sample size SARS-COV-2 infection SARS-CoV-2 pandemic scale screened secondary Secondary outcomes severe COVID-19 severe SARS-CoV-2 Standard of care status Study protocol subject supplemental oxygen supplementary material suspicion Switzerland Symptom the SARS-CoV-2 the WHO their family members Tocilizumab Treatment treatment arm Trial Two interim analyses Two interim analysis virological clearance website WHO WHO ordinal scale with COVID-19 X-ray
[DOI] 10.1186/s13063-020-04976-x PMC 바로가기 [Article Type] Letter

Structured reporting of chest CT provides high sensitivity and specificity for early diagnosis of COVID-19 in a clinical routine setting

흉부 CT의 구조화된 보고는 일상적인 임상 환경에서 COVID-19의 조기 진단을 위해 높은 민감도와 특이성을 제공합니다.

Full Paper

Published on 2021-01-012022-09-12
Journal: The British Journal of Radiology [Category] 진단,

[키워드] Accuracy advance age AUC Chest CT clinical setting clinical suspicion consecutive patient Consensus COVID-19 cut-off cut-off point described diagnosis of COVID-19 diagnostic distribution dominant early diagnosis early phase feasible feature Germany Ground-glass opacities ground-glass opacity male margin Negative predictive value Patient patients with COVID-19 performed positive Positive predictive value Predictive value provide provided pulmonary involvement radiologist reference standard reported Retrospective study ROC analysis RT-PCR RT-PCR testing sensitivity Sensitivity and specificity significantly more specificity suspicion Symptom the epidemic was performed was used
[DOI] 10.1259/bjr.20200574 PMC 바로가기 [Article Type] Full Paper