serine 2 – Page 8 – Communicable Diseases Research

Term Human Placental Trophoblasts Express SARS-CoV-2 Entry Factors ACE2, TMPRSS2, and Furin

용어 인간 태반 영양막은 SARS-CoV-2 진입 인자 ACE2, TMPRSS2 및 푸린을 발현합니다

Research Article

Published on 2021-04-142022-09-10
Journal: mSphere [Category] MERS, SARS, 유전자 메커니즘,

No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection

인간 단핵구 유래 대식세포 감염 및 SARS-CoV-2 감염의 항체 매개 증진에 대한 증거 없음

Cellular and Infection Microbiology

Published on 2021-04-122022-09-12
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome ADE angiotensin-converting enzyme 2 Antibody-dependent enhancement Cell Clinical outcome common cold complexes convalescent COVID-19 patient coronavirus Coronavirus-2 COVID-19 COVID-19 convalescent sera enhancement expressed expressing FcR Human human coronavirus 229E human coronaviruses human monocyte-derived macrophage human monocyte-derived macrophages immunopathological induce infect Infection Inflammatory cytokine Inflammatory responses innate immune response involved macrophages MERS Middle East protease PROTECT receptor receptors SARS-CoV SARS-CoV-2 SARS-COV-2 infection serine 2 serum Spread Support syndrome These cells transmembrane vaccination virus replication with COVID-19
[DOI] 10.3389/fcimb.2021.644574 PMC 바로가기 [Article Type] Cellular and Infection Microbiology

Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19

COVID-19에 대한 SARS-CoV-2의 구조적 및 비구조적 단백질과 치료 표적의 역할

Review

Published on 2021-04-062022-09-11
Journal: Cells [Category] MERS, SARS, 신약개발, 진단, 치료법,

[키워드] 2019-nCoV accessory protein accessory proteins ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Amino acid angiotensin angiotensin converting enzyme 2 Angiotensin-converting enzyme angiotensin-converting enzyme 2 bats cats causative agent cellular entry cleavage components consequence convalescent plasm Coronaviridae coronavirus coronavirus disease Coronavirus disease-19 Coronavirus-2 COVID-19 death downstream drugs encapsulate event family focus functional Genome genomic genomic RNA greater gRNA host cell host cell receptor hosts humans Infection lead mammalian MERS MERS-CoV molecular molecular function molecular target myriad non-structural protein Novel coronavirus polymerase polyproteins positive-sense pp1a pp1ab protease proteolytic cleavage RBD Receptor binding domain referred to replicase respiratory resulting RNA genome role S protein SARS-CoV SARS-CoV-2 SARS-COV-2 infection sequence identity Serine serine 2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus sgRNAs similarity single-stranded Spike protein spike protein of SARS-CoV-2 Spread ssRNA structural protein structural proteins subgenomic mRNA subgenomic mRNAs synthesis target therapeutic therapy TMPRSS2 translated translation transmembrane transmembrane protease serine 2 undergo Vaccine Variability Viral Viral RNA virus
[DOI] 10.3390/cells10040821 PMC 바로가기 [Article Type] Review

High expression of SARS-CoV-2 entry factors in human conjunctival goblet cells

인간 결막 잔 세포에서 SARS-CoV-2 진입 인자의 높은 발현

Review

Published on 2021-04-012022-09-11
Journal: Experimental eye research [Category] MERS, SARS, 유전자 메커니즘, 진단,

Pernio (Chilblains), SARS-CoV-2, and COVID Toes Unified Through Cutaneous and Systemic Mechanisms

피부 및 전신 메커니즘을 통해 통합된 Pernio(Chilblains), SARS-CoV-2 및 COVID 발가락

Review

Published on 2021-04-012022-09-11
Journal: Mayo Clinic proceedings [Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect affecting aldosterone angiotensin Angiotensin II angiotensin-converting enzyme 2 Cell cellular receptor characterized chilblain chilblains clinical coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID COVID-19 COVID-19 severity Cutaneous described Direct discrepancy disease Erythema explain explained feature fingers genetics IFN-I IFN-I response immune immune response immunohistochemistry increase in Infection involved Manifestations many case many cases mechanism Mild Mild disease occur Occurrence pandemic Pathogenesis pathway Patient pernio positive pro-inflammatory protease prothrombotic Renin renin-angiotensin-aldosterone system robust SARS-CoV-2 SARS-CoV-2 cell infection searched Serine serine 2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity Sex sex hormone Sex hormones SIGN skin biopsies skin biopsy susceptibility swelling systemic Toe transmembrane Trigger triggered type I interferon Vascular vasospasm viral cellular infection with COVID-19
[DOI] 10.1016/j.mayocp.2021.01.009 PMC 바로가기 [Article Type] Review

SARS-CoV-2 Entry Related Viral and Host Genetic Variations: Implications on COVID-19 Severity, Immune Escape, and Infectivity

SARS-CoV-2 진입 관련 바이러스 및 숙주 유전자 변이: COVID-19 심각도, 면역 탈출 및 감염성에 미치는 영향

Review

Published on 2021-03-172022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 변종,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus Adhesion Molecule Affect angiotensin antiviral drugs binding Cell contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical determine driving drug enzyme escape Evolution genetic diversity genetic risk Genetic variation Genetic variations Genome geographical regions glycoprotein high risk Host host protein human population human populations immune Immune escape Impact in viral Infectivity integrin intercellular intercellular adhesion molecule Mutation Pathogenesis Pathogens Population Positive selection Precision protease Protein Receptor binding domain Research respiratory S glycoprotein SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 S glycoprotein SARS-CoV-2 variant SARS-CoV-2 variants Serine serine 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity spike glycoprotein susceptibility the cell the SARS-CoV-2 TMPRSS2 transmembrane transmembrane protease serine 2 Transmissibility Transmission variants Variation Viral viral evolution viral S virus virus transmissibility vital role vital roles
[DOI] 10.3390/ijms22063060 PMC 바로가기 [Article Type] Review

Is COVID-19 Gender-sensitive?

COVID-19는 성별에 민감한가요?

Review

Published on 2021-03-012022-09-11
Journal: Journal of neuroimmune pharmacology : the official [Category] 유전자 메커니즘,

TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein

Communication

Published on 2021-02-282022-10-28
Journal: Viruses [Category] COVID-19, MERS,

[키워드] 293T-ACE2 activate acute respiratory syndrome addition Cell cellular cellular entry cleave Coronavirus-2 demonstrated expression facilitate HEK293T Host host proteases human Angiotensin-converting enzyme implication Infection other TTSP pathogenicity plasma protease replication of SARS-CoV-2 SARS-CoV-1 SARS-CoV-2 screened serine 2 severe acute respiratory syndrome-like coronavirus-2 (SARS-CoV-2) spike Spike protein subsequent the SARS-CoV-2 tissue tropism TMPRSS11D TMPRSS13 TMPRSS2 transmembrane transmembrane serine protease TTSP type II transmembrane serine protease (TTSP) Vaccine development Vero E6 cell viral entry process virus spike protein
[DOI] 10.3390/v13030384 PMC 바로가기 [Article Type] Communication

Potential Role of Antioxidant and Anti-Inflammatory Therapies to Prevent Severe SARS-Cov-2 Complications

Review

Published on 2021-02-102022-10-28
Journal: The Cochrane database of systematic reviews [Category] COVID-19,

[키워드] activate Activation acute respiratory syndrome Adjuvant treatments Anti-inflammatory therapy antioxidant caused Complication coronavirus coronavirus disease COVID-19 COVID-19 pandemic COVID-19 pathogenesis domain element entry of SARS-CoV-2 enzyme expression host cell induce inducer Inflammasome Inflammation Inflammatory response inhibit inhibit SARS-CoV-2 inhibitors Injury molecular NF-kB Nrf2 nuclear oxidative oxidative stress pandemic pathogenesis of SARS-CoV-2 pathway Pathways patients Potential Prevent protease radical scavenger receptor Replication reported respiratory viral infection resulting role SARS-CoV-2 serine 2 severe complications severe SARS-CoV-2 shown steroid suppressed transmembrane triggering upregulation Vitamin C while
[DOI] 10.3390/antiox10020272 PMC 바로가기 [Article Type] Review

Molecular recognition in the infection, replication, and transmission of COVID-19-causing SARS-CoV-2: an emerging interface of infectious disease, biological chemistry, and nanoscience

Reviews

Published on 2021-02-052022-10-05
Journal: NPG Asia Materials [Category] 변종, 유전자 메커니즘, 치료제,

[키워드] acute respiratory syndrome adaptive addition angiotensin-converting enzyme 2 Antiviral binding coronavirus coronavirus disease CoV CoV infection COVID-19 CoVs develop epithelial cell form function Genome glycans Host host cell Human IFN IFNs immune response Immunity immunology infected with SARS-CoV-2 Infection Infectious disease interferon involved macaque mechanism Medicine mutated Mutation N-acetylneuraminic acid nuclear outbreak pandemic Pandemics pathway physician platform progeny virion protease Protein receptor Replication researchers RNA SARS-CoV SARS-CoV-2 secretion serine 2 severity SGP sialic acid specificity spike glycoprotein stimulate Structure Symptom the cytokine storm the SARS-CoV-2 Toll-like receptor Transcription transmembrane Transmission Vaccine virus Wuhan
[DOI] 10.1038/s41427-020-00275-8 [Article Type] Reviews