severe cases – Page 8 – Communicable Diseases Research

The Prevalence and Associated Death of Ventricular Arrhythmia and Sudden Cardiac Death in Hospitalized Patients With COVID-19: A Systematic Review and Meta-Analysis

Cardiovascular Medicine

Published on 2022-01-212022-10-31
Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19,

Cytokine Storm in COVID-19: Immunopathogenesis and Therapy

COVID-19의 사이토카인 폭풍: 면역 병인 및 치료

Review

Published on 2022-01-182022-09-12
Journal: Medicina [Category] SARS, 진단,

[키워드] administration affected Allogeneic allogeneic hematopoietic stem cell transplantation Anakinra antibody autoinflammatory disease CAR Care clinically Coagulopathy conditions coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Critically ill critically ill patients cytokine cytokine inhibitors Cytokine storm Cytokines death deregulated disease disease severity effective effort excessive production of cytokines glucocorticoid Glucocorticoids GM-CSF Graft Graft-versus-host disease Hematopoietic stem cell hemophagocytic lymphohistiocytosis Hope hyperinflammatory state IFN-γ IL-1 IL-10 IL-2 IL-6 immune cells immune system IP-10 jak inhibitors leading MCP-1 Methylene blue mitigate multi-organ failure Novel coronavirus novel coronavirus disease overcome pandemic Pathogenesis Patient Plasmapheresis pro-inflammatory cytokines reducing mortality secondary hemophagocytic lymphohistiocytosis secondary to Sepsis severe cases stem cell Stem cell transplantation storm syndrome T-cell tested the cytokine storm the disease therapeutic strategy therapy TNF-α to define Tocilizumab
[DOI] 10.3390/medicina58020144 PMC 바로가기 [Article Type] Review

Collapsing Focal Segmental Glomerulosclerosis in Viral Infections

바이러스 감염에서 국소 분절 사구체 경화증의 붕괴

Review

Published on 2022-01-132022-09-11
Journal: Frontiers in Immunology [Category] 변종, 유전자 메커니즘,

[키워드] activated Acute kidney injury acute viral infection acute viral infections African AKI APOL 1 APOL1 appearance Capillaries cascade cellular characterized Collapsing contributing to COVAN COVID-19 cytokine cytomegalovirus described direct viral infection drug epithelial cells etiologies Evidence Focal focal segmental glomerulosclerosis focus function glomerular glomerular capillaries glomerulopathy glomerulosclerosis hemodynamic instability high risk HIV HIVAN hyperplastic hypertrophic immune response immune responses impairment Infection Injury Ischemia kidney Kidney disease Kidney failure knowledge obliteration Pathogenesis Patient podocyte Podocytes potential mechanism potential mechanisms progression Proteinuria renal epithelial cell risk SARS-CoV-2 SARS-COV-2 infection Segmental Severe case severe cases systemic immune response systemic immune responses systemic inflammatory variant Viral viral entry viral infection viral infections
[DOI] 10.3389/fimmu.2021.800074 PMC 바로가기 [Article Type] Review

Hyperglycemia and blood glucose deterioration are risk factors for severe COVID‐19 with diabetes: A two‐center cohort study

Research Article

Published on 2022-01-082022-11-01
Journal: Journal of medical virology [Category] COVID-19, Fulltext, MERS,

Potential Use of Serum Proteomics for Monitoring COVID-19 Progression to Complement RT-PCR Detection

RT-PCR 검출을 보완하기 위한 COVID-19 진행 모니터링을 위한 혈청 단백질체학의 잠재적 사용

Article

Published on 2022-01-072022-09-11
Journal: Journal of Proteome Research [Category] SARS, 유전자 메커니즘, 치료기술,

[키워드] analyzed approach AUC clinic Clinical practice Course COVID-19 COVID-19 patient COVID-19 progression detection diagnose disease course disease course monitoring effort False negative false negatives high risk inactivated Inactivated serum investigated machine learning machine learning model Magnesium mass spectrometry MONITOR monitoring non-severe cases non-severe group nucleic acid Platelet platelet counts Potential practitioners predict promote Protein proteome proteomics regulated required RNA RT-PCR RT-PCR tests serum Serum protein serum sample serum samples Severe case severe cases severe group Swab symptoms onset the disease viral nucleic acid
[DOI] 10.1021/acs.jproteome.1c00525 PMC 바로가기 [Article Type] Article

Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, Bangladesh

COVID-19 감염의 중증도가 다른 환자의 질병 특성 및 혈청 반응: 방글라데시 다카의 종단 코호트 연구

Research Article

Published on 2022-01-042022-09-12
Journal: PLoS Neglected Tropical Diseases [Category] 진단,

[키워드] addition age age and sex analyzed antibody Antibody Response antibody response against Antibody responses Asymptomatic asymptomatic infection asymptomatic infections biochemical caused Characteristics clinician co-morbid condition co-morbid conditions Community conducted Control COVID-19 COVID-19 disease COVID-19 illness COVID-19 infection CRP CRP level CRP levels D-dimer disease disease severity Disease spectrum elevated enrolled Enrollment evaluate exclusion criteria ferritin ferritin level ferritin levels Follow-up visit follow-up visits Gender geographical region healthy healthy controls help hematological parameter hematological parameters hospital IgG antibodies IgG antibody IgG levels IgM and IgG immunological parameter immunological parameters infected individual Infection levels of antibody longitudinal cohort study longitudinal study lymphocyte lymphocyte counts male many cases Mild Mild disease moderate neutrophil neutrophil count NLR normal range Older age onset of symptom outcome outcomes participant Patient patients patients with COVID-19 predict progression RBD Receptor binding domain responsible risk factor Risk factors SARS-CoV-2 serological response seropositive Severe case severe cases severe COVID-19 disease severe COVID-19 illness severe disease severe disease manifestation severe patients severity of COVID-19 significantly higher Spike protein spike protein of SARS-CoV-2 the disease the spike protein Viral load
[DOI] 10.1371/journal.pntd.0010102 PMC 바로가기 [Article Type] Research Article

COVID-19 autopsy cases: detection of virus in endocrine tissues

코로나19 부검 사례: 내분비 조직에서 바이러스 검출

Article

Published on 2022-01-012022-09-11
Journal: Journal of Endocrinological Investigation [Category] MERS, SARS, 진단, 치료기술,

Evaluation of minocycline combined with favipiravir therapy in coronavirus disease 2019 patients: A case-series study

코로나바이러스 질환 2019 환자에서 파비피라비르 요법과 결합된 미노사이클린의 평가: 사례 시리즈 연구

Article

Published on 2022-01-012022-09-11
Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료제,

[키워드] acute respiratory syndrome adverse event anti-inflammatory activity antibacterial activity Antiviral Chain Reaction changes in chemokine combination therapy Control control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine cytokine and chemokine production Cytokines duration of fever duration of hospitalization Efficacy and safety Endpoint evaluated Favipiravir greater groups hospital Inflammatory cytokines interleukin interleukin-6 interleukin-8 Japan MIN Minocycline monotherapy Negative PCR no difference Patient PCR test polymerase chain polymerase chain reaction reduction reported Retrospective study SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe case severe cases significantly significantly shorter Support therapy Treatment treatment initiation
[DOI] 10.1016/j.jiac.2021.09.016 PMC 바로가기 [Article Type] Article

Characteristic of IgA and IgG antibody response to SARS-CoV-2 infection in an Italian referral COVID-19 Hospital

이탈리아 의뢰 코로나19 병원에서 SARS-CoV-2 감염에 대한 IgA 및 IgG 항체 반응의 특징

Article

Published on 2022-01-012022-09-12
Journal: Internal and Emergency Medicine [Category] SARS, 진단,

T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death

북아프리카 COVID-19 환자의 혈액 내 T 세포 수와 IL-6 농도는 심각한 질병 및 사망에 대한 두 가지 독립적인 예후 인자입니다

Article

Published on 2022-01-012022-09-11
Journal: Journal of leukocyte biology [Category] 바이오마커,

[키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition African Analysis B cells Blood CD4+ T cells CD8+ T cell CD8+ T cells characteristic clinician Concentration coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients cutoff value cytokine cytokine level cytokine levels Cytokines death death group develop disease flow cytometry healthy control healthy controls help high risk IL-10 IL-6 immune parameter immune system independent investigated lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes Mild Mortality multivariate logistic regression multivariate logistic regression analysis natural killer cell Natural killer cells North outcome parameter pathology Patient patients percentage percentages performed Peripheral blood peripheral blood lymphocyte predict Prognosis Prognostic factor receiver operating characteristic respiratory risk ROC ROC curves SARS-CoV2 severe acute respiratory syndrome Coronavirus severe cases severe disease severity severity of illness significant difference significant differences significantly higher statistical difference statistical differences subset survival T cell T cells Th17 Th2 the disease the patient threshold Total two group two groups
[DOI] 10.1002/JLB.4COVA1020-703R PMC 바로가기 [Article Type] Article