Questioning the sex-specific differences in the association of smoking on the survival rate of hospitalized COVID-19 patients입원 한 Covid-19 환자의 생존율에 대한 흡연의 연관성의 성별 관련 차이에 의문Research Article Published on 2021-08-052022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] absence addition adjusted age association cigarette smoking clinical Cohort collected consequence COVID-19 COVID-19 mortality COVID-19 testing Cox proportional hazard Cox proportional hazards model death disease elevated enrolled explain female Health highest highlight hospital Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient ICU admission ICU admissions incidence investigated Kaplan-Meier survival curve Kaplan-Meier survival curves Logistic regression male men Middle East mortality rate North not affect Odds ratio outcome outcomes Patient patients Prevalence proportional hazards model reduce regions Regression model remained reported Result smoker Smokers smoking smoking status stratified by sex survival Survival curves survival rate survival rates Treatment were used worse prognosis [DOI] 10.1371/journal.pone.0255692 PMC 바로가기 [Article Type] Research Article
Impact of Tobacco Smoking on the Risk of COVID-19: A Large Scale Retrospective Cohort StudyObservational Study Published on 2021-08-042022-10-05 Journal: Nicotine & tobacco research : official journal of [Category] SARS, 임상, [키워드] 95% confidence interval age Analysis association attack rate Blood Group body mass index cause Clinical signs conducted coronavirus SARS-CoV-2 COVID-19 COVID-19 infection cross-sectional current had no Hospitalized Impact increased risk indicated Infection investigated IRB less lower risk mechanism median age Odds ratio outbreak paradoxical pathway Patient physiological polymerase chain recent reported Research retained risk SARS-CoV-2 SARS-CoV2 scale Seven severe disease Sex significantly lower smoker smoking smoking status Support susceptibility susceptible the disease Tobacco univariable analysis vessel [DOI] 10.1093/ntr/ntab004 PMC 바로가기 [Article Type] Observational Study
The Health Behaviour of German Outpatient Caregivers in Relation to the COVID-19 Pandemic: A Mixed-Methods StudyArticle Published on 2021-08-032022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] Affect affected Ambulatory care Care Caregiver conducted COVID-19 COVID-19 pandemic cross-sectional survey develop eating behaviour Germany Health health behaviour hygiene increasingly less lifestyle maintain majority measure occupational health Older Outpatient Outpatient Care pandemic participant physical activity PPE Quantitative relation reported smoker Stress Support was increased while [DOI] 10.3390/ijerph18158213 PMC 바로가기 [Article Type] Article
Covid-19, non-Covid-19 and excess mortality rates not comparable across countriesOriginal Paper Published on 2021-08-022022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS, [키워드] addition average calculated cause-specific mortality comparable coronavirus disease country COVID-19 death determine difference explain female Government Health investigated male Mortality mortality and excess mortality rates per country mortality data mortality rate mortality rates other diseases pandemic positive produced proportion public health measure reduced reflected regression analysis reported required residual smoker variables variables associated with Covid-19 and excess mortality rates [DOI] 10.1017/S0950268821001850 PMC 바로가기 [Article Type] Original Paper
Impact of the COVID-19 Pandemic on the Lifestyles and Quality of Life of Women With Fertility Problems: A Cross-Sectional StudyPublic Health Published on 2021-07-192022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, SARS, [키워드] Anxiety Care carried conducted confinement COVID-19 COVID-19 pandemic cross-sectional Depression diet Effect female Female Infertility Fertility fertility problems greater HADS healthy Impact impacted IMPROVE increase in life lifestyle measure medical service moderate no difference participant participated Patient physical Quality Quality of life questionnaire reproductive significant increase smoker Smokers smoking the mean was collected women [DOI] 10.3389/fpubh.2021.686115 PMC 바로가기 [Article Type] Public Health
Th2/Th1 Cytokine Imbalance Is Associated With Higher COVID-19 Risk MortalityTh2/Th1 사이토 카인 불균형은 더 높은 Covid-19 위험 사망률과 관련이 있습니다.Genetics Published on 2021-07-162022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] ACE2 expression addition Admission Affect age airway Analysis analyzed approach Asthma asthma patient asthma patients asthmatic CD4 COVID-19 COVID-19 severe respiratory syndrome cytokine death Deceased determined by died enrichment score evaluated Gene Expression healthy healthy controls Hospital admission hospitalized patient hospitalized patients Imbalance immune response Linear regression male Mortality Mount Sinai Mount Sinai Health System multi-organ inflammatory response nasal epithelium non-infected Older age outcome Patient patient reported patients patients hospitalized phenotype positive predict proteomics respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV2 infection sera serum serum proteomics severe respiratory syndrome Sex significantly smoker Smokers smoking smoking status sputum suggested System T cell T cells T-cells Th1 Th1 pathway Th17 Th2 Th2 pathway the SARS-CoV-2 virus those that survived type 2 helper Variation [DOI] 10.3389/fgene.2021.706902 PMC 바로가기 [Article Type] Genetics
Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1Immunology Published on 2021-07-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 bind cellular receptor chromatin immunoprecipitation chronic COPD coronavirus Coronavirus disease 2019 COVID-19 demonstrated develop Direct downregulate downregulated epithelial cells Evidence human lung identification individual loss of function lung lung epithelial cell lung epithelium mechanism mice Multiple observation patients phenotype potential molecular promoter pulmonary reported represse repression SARS-CoV-2 receptor ACE2 smoker target the SARS-CoV-2 transcriptional regulation upregulate upregulation [DOI] 10.3389/fimmu.2021.648815 PMC 바로가기 [Article Type] Immunology
Expression of SARS-CoV-2 Entry Factors in Human Alveolar Type II Cells in Aging and EmphysemaArticle Published on 2021-07-062022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] ACE2 aging alveolar type II cells ATII cause CD209L Cell described Diffuse alveolar damage disease emphysema expression facilitate Factor Host Human Infection lung transplant Lungs mRNA level Patient patients proliferate protein expression receptor Regulation RT-PCR SARS-CoV-2 SARS-CoV-2 entry factor SARS-COV-2 infection significantly increased smoker Smokers smoking Stress TMPRSS2 TMPRSS2 protease Type upregulation viral entry virus infection western blotting [DOI] 10.3390/biomedicines9070779 PMC 바로가기 [Article Type] Article
Lung cancer patients with COVID-19 in Spain: GRAVID studyObservational Study Published on 2021-07-012022-10-05 Journal: Lung cancer (Amsterdam, Netherlands) [Category] SARS, 임상, [키워드] Admission admitted to ICU age analysed anticancer Anticancer therapy approach Cancer cancer patient Chemotherapy Clinical characteristics correlated Corticosteroid COVID-19 death died disease effective Hospitalization Hospitalized hospitals ICU ICU admission increased risk intensive care unit LDH lung cancer lymphocytopenia majority management mechanical ventilation medical record men Mortality outcome outcomes Patient patients treated PCR-confirmed COVID-19 diagnosis predictor primary endpoint Prognosis Prognostic factor Prospective receiving risk SARS-CoV-2 secondary endpoint severe COVID-19 smoker Spanish stage III therapy treat Treatment use of corticosteroid with COVID-19 [DOI] 10.1016/j.lungcan.2021.05.014 PMC 바로가기 [Article Type] Observational Study
Risk factors of SARS-CoV-2 seroprevalence among hospital employees in Italy: a single-centre study이탈리아 병원 직원 중 SARS-CoV-2 혈청 유병률의 위험 요소: 단일 센터 연구Article Published on 2021-07-012022-09-12 Journal: Internal medicine journal [Category] MERS, SARS, 진단, [키워드] Abbott antibody Antibody testing Blood characteristic Characteristics Cohort Contact COVID-19 cut-off cut-offs DiaSorin eligible enrolled evaluate Factor healthcare healthcare worker high risk hospital identify infected cases Infection Italian nasopharyngeal swab test national health system nosocomial outbreak participant patients positive Prevalence questionnaire risk SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 seroprevalence serology Seropositivity Seroprevalence single hospital smoker subjects Symptom symptomatic undergo was determined with COVID-19 [DOI] 10.1111/imj.15201 PMC 바로가기 [Article Type] Article