Prophylactic potential of honey and Nigella sativa L. against hospital and community-based SARS-CoV-2 spread: a structured summary of a study protocol for a randomised controlled trial병원 및 지역사회 기반 SARS-CoV-2 확산에 대한 꿀과 Nigella sativa L.의 예방 가능성: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-09-152022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 adaptive allergy analyst approved asymptomatic patient blinded Blinding body weight Botany Care care providers chronic infection clinic clinical Clinical management clinical study clinical trial college Community conflict conflict of interest control group coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19-related symptom COVID-19-related symptoms death defined dextrose dissemination doctor Efficacy element Endpoint enrolled evaluate excluded exposure to Final futility high risk Honey hospital hospitalizations incidence include institutional review board Intention interim analysis investigator management guidelines masking moderate National Health Service Nigella Nigella Sativa number objective outcome Pakistan parallel group participant Participants Patient patients per day Placebo placebo group placebo-controlled Primary outcome principal investigator Prophetic Medicine Prophylactic protocol randomisation randomised randomised controlled trial randomization Randomized receive recruited recruitment Registered reported responsible risk Sample size SARS-CoV-2 screened secondary Secondary endpoints severity Site Standard standard care Standardization status Stratification Study protocol supplementary material the patient therapeutic potential therapy Trial university Version water website [DOI] 10.1186/s13063-021-05510-3 PMC 바로가기 [Article Type] Letter
Animal experiments show impact of vaccination on reduction of SARS-CoV-2 virus circulation: A model for vaccine development?SARS-CoV-2 바이러스 순환 감소에 대한 백신 접종의 영향을 보여주는 동물 실험: 백신 개발 모델?Review Published on 2021-09-012022-09-12 Journal: Biologicals : journal of the International Associa [Category] SARS, 진단, [키워드] animal Animal experiment animal model animal models Blood bronchoalveolar clinical development clinical trials COVID-19 disease Efficacy eight experiments exposure Exposure experiments Intention Lungs nasal swab neutralizing antibody predicted reduced reduction retrieved SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 virus shown Standardization tested Transmission trials vaccination Vaccine Vaccine development vaccine platform Viral load viral replication Viral RNA viral shedding virus excretion [DOI] 10.1016/j.biologicals.2021.08.001 PMC 바로가기 [Article Type] Review
Variations in COVID-19 Spread and Control Measures in the Palestinian TerritoriesPublic Health Published on 2021-08-252022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] activity catastrophic Community Control control measures country COVID-19 COVID-19 incidence COVID-19 pandemic East-Jerusalem fatality Gaza Strip Health health system include Infection international organization Intervention Laboratory lack lowest management measure Mortality mortality rate National overcome Palestinian pandemic prevalent protocols risk risk factor Risk factors Spread Standardization Support Surveillance territory the epidemic Travel Variation variety West Bank West Bank—Palestine WHO [DOI] 10.3389/fpubh.2021.736005 PMC 바로가기 [Article Type] Public Health
Quantitative SARS-CoV-2 Spike Antibody Response in COVID-19 Patients Using Three Fully Automated Immunoassays and a Surrogate Virus Neutralization TestArticle Published on 2021-08-192022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Abbott antibody antibody level Area AUC AUC value binding antibody unit binding antibody units chemiluminescent immunoassay CLIA collected correlated COVID-19 COVID-19 infection COVID-19 patients Curve Genscript highest immune response Immune status immunoassay Infection neutralizing antibody Patient Protein quantitation regression analysis response Roche SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 S protein severe disease Siemen Siemens spike Standardization surrogate sVNT symptom onset Test vaccination virus neutralization test [DOI] 10.3390/diagnostics11081496 PMC 바로가기 [Article Type] Article
Distribution and reference interval establishment of neutral‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte ratio (LMR), and platelet‐to‐lymphocyte ratio (PLR) in Chinese healthy adultsResearch Article Published on 2021-08-132022-10-30 Journal: Journal of Clinical Laboratory Analysis [Category] Coronavirus, MERS, SARS, [키워드] age calculated Chinese coronavirus disease COVID‐19 decrease defined Diseases female Gender group healthy limit linear Lymphocyte count lymphocyte‐to‐monocyte ratio male monocyte neutrophil count neutrophil‐to‐lymphocyte ratio NLR Platelet platelet‐to‐lymphocyte ratio promote reference interval Result significant difference significantly higher significantly lower Standardization upper reference limit value were measured [DOI] 10.1002/jcla.23935 PMC 바로가기 [Article Type] Research Article
COVID-19 Vaccine Hesitancy—A Scoping Review of Literature in High-Income CountriesReview Published on 2021-08-132022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 2019 novel coronavirus disease age article CINAHL common conducted Coronavirus disease-19 (COVID-19) country COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines Critical determinant evaluated Factor Factors females form Health heterogeneity Influenza Italy literature medical condition MOST National ranged Region regions reported retrieved review risk SARS-COV-2 infection scoping review Standardization vaccination Vaccine Vaccine acceptance Vaccine hesitancy Vaccines were excluded [DOI] 10.3390/vaccines9080900 PMC 바로가기 [Article Type] Review
Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysisResearch Article Published on 2021-08-122022-10-29 Journal: PLoS Medicine [Category] COVID-19, MERS, SARS, [키워드] 95% CI Accuracy Ag-RDT Ag-RDTs analyses Analysis Antigen articles clinical study Collection comparability Comparisons concern conducted core cycle threshold database dataset datasets Descriptive analysis detect diagnostic diagnostics disease early phase ENhance heterogeneity highest IMPROVE increasingly Luka majority Meta-analysis nasal nasopharyngeal offered overlapping Patient performed polymerase chain QUADAS-2 raised random-effect rapid antigen test Rapid diagnostic test recommendations Registered reported researcher resulting reverse transcription risk of bia RT-PCR SARS-CoV-2 SARS-CoV-2 antigen searched sensitivity Sensitivity and specificity shown Spread Standard Q Standardization Support symptom onset systematic review Testing utility Viral load was used Web of Science [DOI] 10.1371/journal.pmed.1003735 PMC 바로가기 [Article Type] Research Article
Opinion: A serious issue with the standardization of the adenovirus-based COVID-19 vaccines?Letter to the Editor, News and Views Published on 2021-08-062022-10-28 Journal: Archives of Toxicology [Category] COVID-19, MERS, SARS, [키워드] adenovirus-based COVID-19 Standardization [DOI] 10.1007/s00204-021-03126-9 PMC 바로가기 [Article Type] Letter to the Editor, News and Views
Helicopter Emergency Medical Services Transport of COVID-19 Patients in the “First Wave”: A National SurveyEmergency Medicine Published on 2021-08-062022-10-31 Journal: Cureus [Category] COVID-19, [키워드] adjust agency air-purifying respirator Analysis analyzed attribute benefit chose collected conducted coronavirus disease COVID COVID-19 COVID-19 patient COVID-19 patients Critical care transport database demographics Emergency equipment First wave Helicopter helicopter ems infection control Infection prevention and control Infectious disease initial Isolation less majority Measures medical service N95 respirator National Non-COVID-19 observation organization outbreak pandemic pathogen Patient Personal protective equipment Personal protective equipment (PPE) PPE Protective provided reported Research Respirator respiratory virus Result risk separated service Standardization survey suspected patient transfer Transport USA Variability [DOI] 10.7759/cureus.16961 PMC 바로가기 [Article Type] Emergency Medicine
Decreased Mortality Over Time During the First Wave in Patients With COVID-19 in Geriatric Care: Data From the Stockholm GeroCovid StudyObservational Study Published on 2021-08-012022-10-05 Journal: Journal of the American Medical Directors Associat [Category] SARS, 신약개발, 임상, [키워드] 95% CI 95% confidence interval Admission analyzed Care cause changes in clinics COVID-19 COVID-19 pandemic COVID-19 patient death declined Decreased demographics diagnosed with COVID-19 driving explain First wave geriatric Hospitalized In-hospital death incidence incidence rate less Lower Mortality mortality rate Non-COVID-19 non-COVID-19 patient observational study outcome over oxygen saturation pandemic Patient patients patients with COVID-19 pharmacological treatment Poisson regression model proportion remained risk setting Standardization survival survival rate the patient time Treatment vital sign vital signs Wave [DOI] 10.1016/j.jamda.2021.06.005 PMC 바로가기 [Article Type] Observational Study