thrombotic event – Page 8 – Communicable Diseases Research

The Role of P-Selectin in COVID-19 Coagulopathy: An Updated Review

Review

Published on 2021-07-262022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19,

Platelet activation in critically ill COVID-19 patients

Research

Published on 2021-07-172022-10-28
Journal: Annals of Intensive Care [Category] COVID-19,

[키워드] Activation Admission Analysis Biomarker Cohort contribute COVID-19 COVID-19 patient COVID-19 severity Critical Critically ill Critically ill patient cross-sectional cutoff value death described disease severity driving dysregulation elevated enrichment analysis Evidence gene-expression GP1BB Hemostasis hierarchical clustering identify in-hospital mortality increased expression independent intubation marker mechanism Negative predictive value NPV outcomes Platelet platelet activation Platelets Positive predictive value PPBP PPV Predictive Primary hemostasis required Result ROC ROC Curve SELPLG severe coronavirus disease severity Specific supplementary material Thrombo-inflammation thrombotic event upregulated venous
[DOI] 10.1186/s13613-021-00899-1 PMC 바로가기 [Article Type] Research

Cerebral venous thrombosis in a patient with Down syndrome and coronavirus disease 2019: a case report

Case Report

Published on 2021-07-122022-10-30
Journal: Journal of Medical Case Reports [Category] COVID-19, SARS,

Arterial and venous thrombosis in coronavirus 2019 disease (Covid-19): relationship with mortality

Im - Original

Published on 2021-07-042022-10-30
Journal: Internal and Emergency Medicine [Category] COVID-19, MERS,

[키워드] 95% CI age albumin albumin level Analysis arterial Blood level C-reactive protein cardiovascular disease chronic obstructive coagulation test Comorbidity confidence Coronary artery disease Coronary heart disease coronavirus 2019 disease coronavirus disease COVID-19 D-dimer death demographic diabetes died event events Follow-up hazard ratio heart failure hospital IMPROVE In-hospital intensive care interval Laboratory Logistic Mortality multicenter multivariable multivariable Cox regression Patient patients Pneumonia predicted Prognosis Prospective pulmonary disease Ratio Registered reported Result risk SARS-CoV-2 Sex survival thrombosis thrombotic thrombotic event Thrombotic events Treatment venous Venous Thromboembolism Venous thrombosis White blood cells
[DOI] 10.1007/s11739-020-02621-8 PMC 바로가기 [Article Type] Im - Original

High Prevalence of Anti-PF4 Antibodies Following ChAdOx1 nCov-19 (AZD1222) Vaccination Even in the Absence of Thrombotic Events

Article

Published on 2021-07-012022-10-28
Journal: Vaccines [Category] COVID-19,

Major bleeding complications in critically ill patients with COVID-19 pneumonia

COVID-19 폐렴 중환자의 주요 출혈 합병증

Article

Published on 2021-07-012022-09-11
Journal: Journal of Thrombosis and Thrombolysis [Category] 바이오마커,

[키워드] Anticoagulant Anticoagulants anticoagulation bleeding bleeding event bleeding events bleeding risk coagulation disorders coagulation test coagulation tests Cohort collected Complication Concentration COVID-19 COVID-19 patient COVID-19 patients COVID-19 pneumonia Critically ill patient D-dimer D-dimers decrease demographics disorder Evolution examined fibrinogen heparin High dose hyperinflammation ICU ICU admission Inflammation initial intensive care intensive care unit investigated Major major bleeding mechanical ventilation MONITOR MOST occurred outcome overdose Patient patients with COVID-19 Pneumonia Prevent promoted receiving reduced risk Standard dose therapeutic anticoagulation Thromboprophylaxis thrombosis thrombotic thrombotic event Thrombotic events thrombotic risk treated was measured with COVID-19
[DOI] 10.1007/s11239-021-02403-9 PMC 바로가기 [Article Type] Article

Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy

Research article

Published on 2021-07-012022-10-05
Journal: International journal of biological macromolecules [Category] SARS, 신약개발,

[키워드] ACE2 ACE2 binding ACE2angiotensin-converting enzyme 2 Analysis angiotensin-converting enzyme 2 Anti-SARS-CoV-2 Activity antiviral activity Antiviral compound available data CDCCenters for Disease Control and Prevention Cell Centers for Disease Control and Prevention Complete Coronavirus disease 2019 COVID-19 COVID-19coronavirus disease 2019 disrupting drug Drug repurposing Eagle's Minimum Essential Medium Efficacy EMEMEagle's Minimum Essential Medium epithelia evaluated FBSfetal bovine serum FDA FDAU.S. Food and Drug Administration fetal bovine serum high throughput virtual screening HTVShigh throughput virtual screening IC50 identity IDidentity in-silico In-vitro include independent indicated interact Interaction LMWHlow-molecular-weight heparin Low-molecular-weight heparin mutant nasal Neuropilin-1 Novel coronavirus NRP1neuropilin-1 P/Spen strep pandemic Pathogens pathology PBSphosphate-buffered saline PDBProtein Data Bank pen strep phosphate-buffered saline potential transmission Prevent Protein Data Bank RBDReceptor Binding Domain Receptor binding domain reducing reported SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 Spike protein Spike proteins Support thrombotic event TMPRSS2transmembrane serine protease 2 transmembrane serine protease 2 Transmission treat U.S. Food and Drug Administration UFHunfractionated heparin unfractionated heparin United States variant viral entry Viremia Virtual screening virus assay with COVID-19
[DOI] 10.1016/j.ijbiomac.2021.04.148 [Article Type] Research article

Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes: data from the COVID-PREDICT cohort study in The Netherlands

Research Article

Published on 2021-06-262022-10-30
Journal: Journal of Diabetes and Metabolic Disorders [Category] COVID-19,

Inflammatory Mechanisms in COVID-19 and Atherosclerosis: Current Pharmaceutical Perspectives

COVID-19 및 죽상동맥경화증의 염증 기전: 현재의 약학적 관점

Review

Published on 2021-06-212022-09-12
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-inflammatory agents anti-inflammatory treatment Arrhythmias Atherosclerosis atherosclerotic atherosclerotic heart disease cardiovascular event Cardiovascular events cardiovascular system caused coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 current disease endothelial injury excess mortality heart disease immunomodulator immunomodulators Inflammation inflammatory pathway inflammatory pathways involved Mortality myocardial injury myocarditis pharmaceutical reduction SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe complications similarities similarity systemic inflammatory response thrombotic thrombotic event Treatment Venous Thromboembolism
[DOI] 10.3390/ijms22126607 PMC 바로가기 [Article Type] Review

Massive Arterial Cerebral Thrombosis in a 59-year old Female Patient With Severe COVID-19

Family/General Practice

Published on 2021-06-092022-10-31
Journal: Cureus [Category] COVID-19,