Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesisResearch Article Published on 2020-05-132022-10-04 Journal: Journal of medical virology [Category] MERS, SARS, 치료제, [키워드] adaptive Adaptive immune response Adaptive immunity Analysis antiviral drugs applied cause caused complications coronavirus COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Disease progression early phase epithelial cell Host immune response Immunity implication Infection Influenza Influenza virus innate immune response Innate immunity Interaction lung mathematical Mortality opposite pandemic Pathogenesis patients potential treatment option SARS‐CoV‐2 virus SARS‐CoV‐2 severity Suppressing target cell‐limited model the timing viral clearance Viral load viral pathogenesis virus viruses [DOI] 10.1002/jmv.25866 PMC 바로가기 [Article Type] Research Article
Pattern Recognition Receptor Signaling and Innate Responses to Influenza A Viruses in the Mallard Duck, Compared to Humans and ChickensArticle Published on 2020-05-122023-05-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] Fulltext, 조류인플루엔자, [키워드] duck Influenza Innate immunity Reservoir host tropism [DOI] 10.3389/fcimb.2020.00209 PMC 바로가기
BCG-induced trained immunity: can it offer protection against COVID-19?Comment Published on 2020-05-112023-06-18 Journal: Nature reviews. Immunology [Category] Fulltext, SARS, [키워드] Innate immunity Live attenuated vaccines SARS-CoV-2 [DOI] 10.1038/s41577-020-0337-y PMC 바로가기 [Article Type] Comment
Porcine Epidemic Diarrhea Virus and the Host Innate Immune ResponseReview Published on 2020-05-112022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Antiviral cause coronavirus country CoV CoVs cytokine Defense diarrhea disrupt effective vaccine effector elicit epidemic diarrhea evade expression help highlight Host IFN antagonist IFN response IFNs immune immune evasion induce Infection Innate innate immune innate immune response Innate immunity Interaction involved mechanism pathway PEDV Porcine epidemic diarrhea virus provide response robust Type I IFN viral infections Viral RNA virus watery [DOI] 10.3390/pathogens9050367 PMC 바로가기 [Article Type] Review
Could BCG Vaccination Induce Protective Trained Immunity for SARS-CoV-2?Immunology Published on 2020-05-082022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] analyzed BCG BCG vaccination caused children Contagion correlated country COVID-19 death deaths immune response Immunity Inclusion induce Infection Innate immunity Mortality Mycobacterium tuberculosis National non-specific pandemic pathogen Pathogens positive PROTECT public health reduce SARS-CoV-2 SARS-CoV-2 pandemic shown thought trained immunity Treatment Tuberculosis vaccination Vaccine Vaccines variety [DOI] 10.3389/fimmu.2020.00970 PMC 바로가기 [Article Type] Immunology
Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus InfectionImmunology Published on 2020-05-082022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, Fulltext, MERS, 조류인플루엔자, [키워드] activate carrier conserved contributed coronavirus Coronaviruses cytoplasmic domain double-stranded RNA Endosomes Evolution gene loss genomics study Health Helicase Host host tissue humans Hypothesis IFIH1 inactivated Infection Inflammation Innate innate immune response Innate immunity mammals MDA5 Mutation pangolin pangolins performed Protein provided reducing Research RNA RNA sensor sensor shown significantly TLR Tolerance Toll-like receptor viral infection Viral RNA virus Z-DNA Z-RNA ZBP1 zoonosis zoonotic infection [DOI] 10.3389/fimmu.2020.00939 PMC 바로가기 [Article Type] Immunology
Could nasal nitric oxide help to mitigate the severity of COVID-19?Article Published on 2020-05-062023-06-16 Journal: Microbes and infection [Category] MERS, SARS, [키워드] breathing coronavirus COVID-19 Innate immunity nitric oxide [DOI] 10.1016/j.micinf.2020.05.002 PMC 바로가기 [Article Type] Article
The Microbiota Contributes to the Control of Highly Pathogenic H5N9 Influenza Virus Replication in DucksArticle Published on 2020-05-042023-06-02 Journal: Journal of Virology [Category] 조류인플루엔자, [키워드] avian viruses duck Enteric viruses immunoglobulins Influenza Innate immunity interferons microbiota microflora normal flora. [DOI] 10.1128/JVI.00289-20 PMC 바로가기
Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signalingarticle Published on 2020-04-302024-09-01 Journal: Journal of Microbiology [Category] 폐렴구균 감염증, [키워드] Innate immunity PepN signaling pathway Streptococcus pneumoniae virulence [Article Type] article
Babesia microti Confers Macrophage-Based Cross-Protective Immunity Against Murine Malaria바베시아 미크로티는 마우스 말라리아에 대한 대식세포 기반의 교차 보호 면역을 부여한다.Original Research Published on 2020-04-292024-08-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] Babesia microti babesiosis cross-protection Infection Innate immunity macrophages malaria Plasmodium chabaudi [DOI] 10.3389/fcimb.2020.00193 PMC 바로가기 [Article Type] Original Research