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[키워드] activate addressed Administered Analysis anti-SARS-CoV-2 antibodies antibody antibody combination antibody-based therapies antibody-based therapy Blood blood plasma cause Cell cells changed chimeric circulating Combination convalescent plasma coronavirus COVID-19 COVID19 creating effective vaccine Effective vaccines Effectiveness effort elicited eLife Epitopes escape evade Frequency functional Genome Health HIV host cells Human human cells human population human populations immune immune response immune system in some individual infect Infection Influenza kill Laboratory limit low frequencies maintain monoclonal antibodies monoclonal antibody mutant mutant virus mutate mutated Mutation N-terminal domain natural infection neutralize Neutralizing antibodies neutralizing antibody neutralizing epitopes New coronavirus Patient Population populations Prevent produced Prophylactic Proteins question RBD Receptor-binding domain Recovered COVID-19 patients reporter Research SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 spike protein SARS-CoV-2 variant selected Sequencing Spike protein Spike proteins Structure structures target the antibody the disease the receptor-binding domain the SARS-CoV-2 the spike protein the strongest therapeutic Therapies treated Trigger vaccination Vaccine Vaccines variant Viral protein Viral proteins virus virus mutation virus particle virus particles viruses VSV were infected
[DOI] 10.7554/eLife.61312 PMC 바로가기 [Article Type] Research Article