Association of total and neutralizing SARS-CoV-2 spike -receptor binding domain antibodies with epidemiological and clinical characteristics after immunization with the 1 st and 2 nd doses of the BNT162b2 vaccineBNT162b2 백신의 1차 및 2차 접종 후 역학 및 임상 특성을 갖는 총 및 중화 SARS-CoV-2 스파이크 수용체 결합 도메인 항체의 연관성Article Published on 2021-09-242022-09-11 Journal: Vaccine [Category] SARS, 진단, 치료기술, [키워드] age antibody antibody levels association binding domain BMI BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine BNT162b2 vaccine Clinical characteristics clinical parameter Clinical parameters Cohort correlation COVID-19 COVID-19 vaccine dose elicited epidemiological females Final groups healthcare worker Immunity immunization Immunosuppressive medication immunosuppressive medications IQR median NAbs negatively affected Neutralizing Neutralizing antibodies neutralizing antibody Older age participant positive Protective Protein RBD Receptor binding domain SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein second dose significant difference smoking Spearman spike Spike protein statistical analysis statistically significant systemic adverse event systemic adverse events the vaccine vaccine dose vaccine doses was performed [DOI] 10.1016/j.vaccine.2021.07.067 PMC 바로가기 [Article Type] Article
Mediating Effect of Chronic Illnesses in the Relationship Between Psychological Distress and COVID-19 Vaccine AcceptanceOriginal Articles Published on 2021-09-222022-10-28 Journal: Asia-Pacific Journal of Public Health [Category] COVID-19, Fulltext, SARS, [키워드] acceptance addition age analyses chronic Chronic illness chronic illnesses conducted COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccine acceptance cross-sectional demographic factor demonstrated Effect Gender Malaysia Mediating mediating effect Mediation analysis mental health National participant Psychological distress psychological health relationship significantly the vaccine Vaccine was performed [DOI] 10.1177/10105395211047868 PMC 바로가기 [Article Type] Original Articles
COVID-19 Vaccine Perceptions and Differences by Sex, Age, and Education in 1,367 Community Adults in OntarioPublic Health Published on 2021-09-222022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Adults age analysis of variance Attitudes Community COVID-19 COVID-19 vaccine cross-sectional difference education effort examined female female participant females FIVE global pandemic Hesitancy hesitancy rate individual individuals investigated lack less Older pandemic participated Perception public health messaging receive reported Seven Sex Side effect significantly significantly lower subgroups targeting the vaccine vaccination Vaccine Vaccine hesitancy [DOI] 10.3389/fpubh.2021.719665 PMC 바로가기 [Article Type] Public Health
Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase맹검 단계 완료 시 mRNA-1273 SARS-CoV-2 백신의 효능Clinical Trial Published on 2021-09-222022-09-25 Journal: The New England Journal of Medicine [Category] Fulltext, MERS, 신약개발, 임상, 진단, [키워드] 1:1 95% CI 95% confidence interval acute respiratory syndrome age Analysis assigned asymptomatic infection authority baseline blinded completion conditions confirmed case coronavirus coronavirus disease Cutoff development Efficacy Efficacy and safety Emergency use enrolled Evidence Follow-up groups high risk include injection Injections interim analysis Intramuscular injection mRNA-1273 mRNA-1273 vaccine observer-blinded Open-label participant phase Phase 3 Placebo placebo-controlled clinical trial primary end point protocol Racial Randomly receive reported Result safety profile SARS-CoV-2 SARS-COV-2 infection severe disease the median the placebo group The United States the vaccine Trial vaccine efficacy Volunteer [DOI] 10.1056/NEJMoa2113017 PMC 바로가기 [Article Type] Clinical Trial
Effect of SARS-CoV-2 mRNA vaccination in MS patients treated with disease modifying therapies질병 변형 요법으로 치료받은 다발성 경화증 환자에서 SARS-CoV-2 mRNA 백신 접종의 효과Observational Study Published on 2021-09-222022-09-12 Journal: EBioMedicine [Category] MERS, 임상, 진단, [키워드] Affect analyzed anti-CD20 therapy anti-CD20 treatment antibody antigens assessments Blood blood collection BNT162b2 BNT162b2 vaccine Cellular immune response contribute coronavirus correlated decrease detectable disease Effect electrochemiluminescence immunoassay elicit evaluate the effect finding Follow-up funding humoral immune response Immunomodulatory therapies interval Italian Linear regression Moderna mRNA vaccination mRNA vaccine mRNA-1273 mRNA-based SARS-CoV-2 vaccines multicenter cohort study Multiple multiple sclerosis multivariable multivariable analysis Patient patients treated reduced SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 vaccine sclerosis second dose serological assessment significantly the vaccine therapy untreated patients vaccination Vaccine vaccine dose Vaccines [DOI] 10.1016/j.ebiom.2021.103581 PMC 바로가기 [Article Type] Observational Study
Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in PigsResearch Article Published on 2021-09-212022-10-29 Journal: mBio [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition Administered Adverse reaction Antigen approved B.1.1.7 B.1.351 candidate Combination coronavirus coronavirus disease coronavirus vaccine COVID-19 dose Effectiveness Efficacy expressing HexaPro Immunity immunogenic immunogenicity include induce intramuscular intranasal intranasally mucosal NDV newcastle disease virus P.1 pig pig model PIGS prefusion conformation proline substitution prolines reactivity responses Safe Safety SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccine Serum neutralizing antibody spike spike variant tested the vaccine Vaccine [DOI] 10.1128/mBio.01908-21 PMC 바로가기 [Article Type] Research Article
Attitude towards COVID 19 vaccines and vaccine hesitancy in urban and rural communities in Tamil Nadu, India – a community based surveyResearch Published on 2021-09-212022-10-28 Journal: BMC health services research [Category] COVID-19, SARS, [키워드] 95% CI adverse effect adverse effects approved Attitude Attitudes can be used Cluster cluster analysis Clusters Community conducted country COVID 19 cross develop Emergency use group India individual individuals natural immunity objective positive attitude Prevalence question random response Result Safe second selected the vaccine Vaccine Vaccine hesitancy Vaccines was used while women [DOI] 10.1186/s12913-021-07037-4 PMC 바로가기 [Article Type] Research
A Rare Variant of Guillain-Barre Syndrome Following Ad26.COV2.S VaccinationInternal Medicine Published on 2021-09-212022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Ad26.COV2.S Ad26.COV2.S vaccine adenovirus vaccine adenovirus-based adverse event approved Autoimmune caused coronavirus disease Course COVID-19 COVID-19 vaccine covid-19 vaccine complication diagnostic drug effective Emergency use EUA FDA female food global pandemic guillain-barre syndrome (gbs) healthy hospital New nine Prevent receiving reported Safe SARS-CoV-2 the United State the vaccine US FDA vaccination Vaccine Vaccine adverse events vaccine adverse reactions [DOI] 10.7759/cureus.18153 PMC 바로가기 [Article Type] Internal Medicine
Factors affecting Pakistani young adults’ intentions to uptake COVID‐19 vaccination: An extension of the theory of planned behaviorOriginal Article Published on 2021-09-202022-10-28 Journal: Brain and Behavior [Category] COVID-19, MERS, SARS, [키워드] affecting Aside concerning conducted COVID‐19 COVID‐19 vaccination examined extension Factor fear of COVID‐19 individual information Intention media participant Perceived perceived infectability protection motivation theory recruited Result the vaccine Theory of Planned Behavior Treatment vaccination Vaccine [DOI] 10.1002/brb3.2370 PMC 바로가기 [Article Type] Original Article
SAS: A Platform of Spike Antigenicity for SARS-CoV-2Cell and Developmental Biology Published on 2021-09-202022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] antigenic antigenic resistance antigenic sites antigenic variants antigenicity assays B.1.351 carried circulating complement Coverage Effectiveness epitope Epitopes experiments GISAID include mAb mAbs monoclonal antibody mutant mutants mutated outbreak Perspective platform predicted Protein provided reactivity reduce Region SARS-CoV-2 SARS-CoV-2 antibody SAS sera shown South Africa spike Spike protein Strains the vaccine unique Vaccine variant variants [DOI] 10.3389/fcell.2021.713188 PMC 바로가기 [Article Type] Cell and Developmental Biology