immune responses – Page 88 – Communicable Diseases Research

Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina

아르헨티나에서 SARS-CoV-2 면역 상태, 혈청 유병률 및 회복기 혈장 평가를 위한 긴급 대응

Research Article

Published on 2021-01-142022-08-13
Journal: PLoS Pathogens [Category] Biochemistry, 진단, 치료기술,

Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein

1

Published on 2021-01-122022-10-29
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19,

Severe COVID-19 and Sepsis: Immune Pathogenesis and Laboratory Markers

Review

Published on 2021-01-122022-10-29
Journal: Microorganisms [Category] COVID-19,

[키워드] accompanied acute respiratory syndrome changes in chemokine clinical picture Coagulation condition coronavirus country COVID-19 COVID-19 infection COVID-19 pathogenesis Critical cytokine Cytokine storm Cytokines event Factor Host Hypothesis immune response immune responses include Inflammation inflammatory immune response inflammatory reactions involved lung damage management multiorgan failure novel coronavirus disease outbreak outcome pathogenesis of COVID-19 Patient plasma progression Proinflammatory cytokine Quantitative SARS-CoV-2 Sepsis Serum level severe COVID-19 similarity the disease therapy thought Vascular Viral load viral replication virus
[DOI] 10.3390/microorganisms9010159 PMC 바로가기 [Article Type] Review

Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

COVID-19 임상 합병증을 표적으로 하는 SARS-CoV-2 수명 주기, 병태생리학 및 합리화된 치료에 대한 통찰력

Review

Published on 2021-01-122022-08-13
Journal: Journal of Biomedical Science [Category] Biochemistry, COVID-19, MERS,

[키워드] “cytokine storm” ACE2 activate Adaptive immune response adverse effect adverse effects approach approaches ARDS AT1R clinical complication collateral tissue damage complications of COVID-19 COVID-19 CTSB Cytokine storm distress expression gastrointestinal tract Host human gene hyper-cytokinemia immune responses Infection infection rate infection rates Inflammation inflammatory immune response insight life cycle life-threatening mitigate multi-organ collapse organotropism of SARS-CoV-2 pathobiology of COVID-19 Pathologies pathophysiology Phase 1 Phase 2 Propagation respiratory respiratory and gastrointestinal tract respiratory distress Respiratory distress syndrome robust SARS-CoV-2 SARS-CoV-2 life cycle Sex Signaling Support suppress syndrome systemic failure tissue tissue damage tissues TMPRSS2 Treatment Trigger triggered triggers two-phase disease Viral viral infection virus virus antigen presentation virus transmission
[DOI] 10.1186/s12929-020-00703-5 PMC 바로가기 [Article Type] Review

An overview of Betacoronaviruses-associated severe respiratory syndromes, focusing on sex-type-specific immune responses

Review

Published on 2021-01-102022-11-01
Journal: International immunopharmacology [Category] COVID-19, MERS,

[키워드] Abstract Activation acute respiratory illness Anti-viral approaches autoimmune reactions beta-coronavirus bi-allelic blood circulation coronavirus COVID-19 COVID19 disease epidemiological expression Fatality rate feature female females Frequency Genes Host immune response IFN immune Immune cell immune protection immune response immune responses immune system Immunotherapy inactive Infection infection rate information involved less male MERS MERS-CoV Middle East pathogen Regulatory respiratory respiratory infection responsible robust SARS SARS-CoV-1 SARS-CoV-2 similarity susceptibility susceptible the antibody TLR7 Treatment Vaccine development Variation viral infections Viral load X-linked β-CoVs
[DOI] 10.1016/j.intimp.2021.107365 PMC 바로가기 [Article Type] Review

Evaluation of the usability of various rapid antibody tests in the diagnostic application for COVID-19

코로나19 진단에 다양한 신속항체검사 활용성 평가

Clinical Trial

Published on 2021-01-072022-08-07
Journal: Annals of Clinical Biochemistry [Category] 임상, 진단, 치료기술,

[키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 IgG antibody Antibody detection Antibody test antibody tests chemiluminescent immunoassay collected Concordance coronavirus COVID-19 COVID-19 pandemic detect diagnostic early diagnosis exhibited genomic RNA IgG IgG response IgG responses IgM IgM response IgM responses immune response immune responses immunochromatography initial investigated Laboratory test Laboratory tests Patient performed polymerase chain polymerase chain reaction positive quantitative antibody test quantitative test Rapid rapid antibody test Rapid antibody tests Rapid test Rapid tests respiratory Result reverse transcription reverse transcription polymerase chain reaction RT-PCR RT-PCR diagnosis RT-PCR testing SARS-CoV-2 sensitivity serum sample serum samples severe acute respiratory syndrome Coronavirus Standardization suggested test results the timing Usability
[DOI] 10.1177/0004563220984827 PMC 바로가기 [Article Type] Clinical Trial

Immunogenicity of Multiple Doses of pDNA Vaccines against SARS-CoV-2

Article

Published on 2021-01-062022-10-28
Journal: Pharmaceuticals [Category] COVID-19,

[키워드] Activation acute respiratory syndrome antibody Antibody Response binding candidate cellular immune responses comparable coronavirus coronavirus disease COVID-19 COVID-19 vaccine death dose doses effective elicit full-length S globular head highest immune responses Immunity immunogenicity induce interferon Limited long-lasting magnitude marker mice Multiple natural infection Neutralizing antibodies Neutralizing antibody response neutralizing antibody responses Pandemics pDNA Plasmid preclinical data Reinfection required robust S-specific antibody SARS-CoV-2 SARS-CoV-2 vaccine Serum level Support translational Undetermined Vaccine viral spike virus Wuhan, China
[DOI] 10.3390/ph14010039 PMC 바로가기 [Article Type] Article

A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity

SARS-CoV-2 감염 환자에 대한 종단 연구는 중화 항체와 COVID-19 중증도 사이에 높은 상관관계가 있음을 보여줍니다

Article

Published on 2021-01-062022-09-11
Journal: Cellular and Molecular Immunology [Category] Fulltext, MERS, 변종, 진단,

[키워드] absence anti-Spike IgG anti-spike IgG levels antibody Asymptomatic Cohort contribute coronavirus correlated strongly COVID-19 COVID-19 severity Critical cross-neutralization D614G mutation disease disease severity disease symptom elicited Endemic Europe exhibited forms generate had no Health policy heterogeneous high correlation human coronavirus human coronaviruses humoral Humoral response immune correlate immune correlates immune response immune responses individual Infection infections intensive care intensive care unit intensive care units live SARS-CoV-2 Mild symptom mild symptoms NAb NAb activity NAb titers NAbs neutralization neutralizing antibody other coronaviruses Particle Pathogenesis pathogenesis of SARS-CoV-2 Patient Prognostic markers Protective Protein pseudotyped public health qPCR Reinfection required retroviruses reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected patient SARS-CoV-2-infected patients serum sample serum samples spike Spike protein the SARS-CoV-2 the spike protein understanding Vaccine development variant Viral viral infection viral surface
[DOI] 10.1038/s41423-020-00588-2 PMC 바로가기 [Article Type] Article

Recent endemic coronavirus infection is associated with less-severe COVID-19

최근의 풍토병 코로나바이러스 감염은 덜 심각한 COVID-19와 관련이 있습니다

Article

Published on 2021-01-042022-09-11
Journal: The Journal of Clinical Investigation [Category] MERS, 진단, 치료기술,

Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex

COVID-19의 사이토카인 방출 증후군: 선천성 면역, 혈관 및 혈소판 병원성 요인은 질병의 중증도와 성별이 다릅니다.

Clinical Trial

Published on 2021-01-012022-09-25
Journal: Journal of leukocyte biology [Category] SARS, 바이오마커, 임상, 진단,

[키워드] Activation acute illness addition age Analysis analyzed association Biomarker CD40L Characteristics clinical feature Clinical features Cluster Cohort controls COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines disease disease pathology disease severity examined Factor females FGF fibroblast fibroblast growth factor growth Growth factors Health Health crisis highlight Hospitalized ICU admission identify IL-13 IL-4 immune immune response immune responses Immunopathogenesis Inflammatory cytokines Innate Innate immunity IP10 male pathogenic Patient PDGF Plasma cytokine Platelet platelet-derived growth factors Protein public health crisis risk severe disease Severity of disease Sex significant increases in syndrome Treatment understanding Vascular Vasculitis with COVID-19
[DOI] 10.1002/JLB.3COVA0820-410RRR PMC 바로가기 [Article Type] Clinical Trial