eight – Page 89 – Communicable Diseases Research

Rapid Response to Drive COVID-19 Research in a Learning Health Care System: Rationale and Design of the Houston Methodist COVID-19 Surveillance and Outcomes Registry (CURATOR)

Original Paper

Published on 2021-02-232022-10-31
Journal: JMIR Medical Informatics [Category] COVID-19,

Investigation of Nasal/Oropharyngeal Microbial Community of COVID-19 Patients by 16S rDNA Sequencing

Article

Published on 2021-02-232022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, MERS,

Prevalence of comorbidity in Chinese patients with COVID-19: systematic review and meta-analysis of risk factors

중국 코로나19 환자의 동반질환 유병률: 위험인자에 대한 체계적인 검토 및 메타분석

Meta-Analysis

Published on 2021-02-222022-09-01
Journal: BMC Infectious Diseases [Category] MERS, 진단,

[키워드] 95% CI 95%CI acute lung injury acute respiratory distress acute respiratory distress syndrome ARDS article Cancer cardiovascular disease cerebrovascular Cerebrovascular disease characterized Chinese patient Chronic kidney disease chronic liver disease Chronic Liver Diseases chronic obstructive chronic obstructive pulmonary disease CKD CLD CNKI Comorbidities Comorbidity condition COPD coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 progression COVID-19 severity Deterioration develop diabete diabetes disease disease severity eight exhibited fatigue Fever followed by General population greater hypertension IMPROVE Infection prevention Infectious disease Kidney disease Lung injury malignancy manifestation Meta-analysis Mortality no correlation obstructive pulmonary disease outcome Patient performed Prevalence Prognosis pulmonary disease reported respiratory distress Respiratory distress syndrome Result resulting risk risk factor Risk factors searched severity subgroup supplementary material syndrome systematic review the strongest Treatment strategies treatment strategy underlying disease underlying diseases Web of Science
[DOI] 10.1186/s12879-021-05915-0 PMC 바로가기 [Article Type] Meta-Analysis

Cardiovascular risk factors and COVID-19 outcomes in hospitalised patients: a prospective cohort study

Infectious Diseases

Published on 2021-02-222022-10-28
Journal: BMJ Open [Category] COVID-19, Fulltext, MERS,

[키워드] 95% CI Admission Affect age age and sex analysed Analysis association cardiovascular cardiovascular disease Clinical course Cohort COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients Cox regression Cox regression analysis CVD determine diabete died discharged dyslipidaemia eight evaluated Factor general diabetes hospitalisation hospitalised hospitalised COVID-19 patient hospitals hypertension ICU ICU admission increased mortality increased risk independent intensive & critical care intensive care Ischaemic heart disease Kaplan-Meier measure medication men Mortality objective outcome outcomes Palliative care participant Patient patients PCR positive COVID-19 Prevalence Primary outcome prospective cohort study Prospective Study recent Result risk risk factor Risk factors secondary outcome setting the patient therapy Thorax university hospital vascular medicine were used
[DOI] 10.1136/bmjopen-2020-045482 PMC 바로가기 [Article Type] Infectious Diseases

Intra-host variation and evolutionary dynamics of SARS-CoV-2 populations in COVID-19 patients

COVID-19 환자에서 SARS-CoV-2 집단의 숙주 내 변이 및 진화 역학

Research

Published on 2021-02-222022-08-13
Journal: Genome Medicine [Category] MERS, 변종, 유전자 메커니즘,

[키워드] allele frequency analyzed anatomic site bottleneck bottleneck events bottlenecks causative agent characterized collected Consensus consensus genome coronavirus COVID-19 COVID-19 patient death distribution driven by Dynamics eight event Evolution evolutionary dynamics gastrointestinal tract Genetic genetic diversity Genotype High-throughput sequencing Intra-host Intra-host variant iSNV iSNVs knowledge metatranscriptomic MOST Mutation nucleotide Patient patients with COVID-19 polymorphic site Population populations respiratory respiratory tract Result RNA viruses SARS-CoV-2 SARS-CoV-2 genome Sequencing Single nucleotide variant single nucleotide variation supplementary material the SARS-CoV-2 genome variants Variation Viral virus Virus-host interaction Virus-host interactions
[DOI] 10.1186/s13073-021-00847-5 PMC 바로가기 [Article Type] Research

Medical student remote eConsult participation during the COVID-19 pandemic

Research Article

Published on 2021-02-222022-10-28
Journal: BMC Medical Education [Category] Coronavirus, MERS,

Innate Receptor Activation Patterns Involving TLR and NLR Synergisms in COVID-19, ALI/ARDS and Sepsis Cytokine Storms: A Review and Model Making Novel Predictions and Therapeutic Suggestions

Review

Published on 2021-02-202022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS,

[키워드] “cytokine storm” activate Activation acute lung injury acute lung injury (ALI) acute respiratory distress acute respiratory distress syndrome (ARDS) Bacterial Bacterial coinfection characteristic characterized Combination coronavirus COVID-19 Cytokine release syndrome Cytokine storm effective eight Evidence exhibiting fungal fungal coinfection Fungal infection fungal infections healthy control hyperinflammation implication Infection Innate Innate immunity Interaction Involving Making mechanism melatonin microbes Mild mild cases mild COVID-19 patient Model NLR NLRP3 novel nucleotide-oligomer-recognition-domain-like receptors (NLR) oligomerization outlined pattern prediction receptor respiratory resulting review SARS-CoV-2 Sepsis severe COVID-19 severe COVID-19 patients suggestion Symptoms syndrome synergistic synergy therapeutic TLR TLR antagonists TLR2 TLR3 TLR4 TLR7 TLR9 Toll-like receptor toll-like receptors (TLR) treating COVID-19
[DOI] 10.3390/ijms22042108 PMC 바로가기 [Article Type] Review

Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2

SARS-CoV-2에 대한 프로테아제 억제제의 컴퓨터 선택성 평가

Article

Published on 2021-02-192022-09-10
Journal: International Journal of Molecular Sciences [Category] MERS, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assessment attrition binding caspase caspase-3 cathepsin chymase Compound conducted coronavirus eight factor Xa Health high risk inhibit inhibitors inhibitors of SARS-CoV-2 M pro molecular molecular docking molecular dynamics molecular target pandemic protease Proteases protocol reported researcher respiratory SARS SARS-CoV M SARS-CoV-2 screened selected selectivity severe acute respiratory syndrome Coronavirus structure-based design target targets thrombin Toxicity UCHL1 urgency Viral viral replication
[DOI] 10.3390/ijms22042065 PMC 바로가기 [Article Type] Article

Knowledge, attitude and practice towards COVID-19 among health professionals in Ethiopia: A systematic review and meta-analysis

Research Article

Published on 2021-02-192022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS,

CANPT Score: A Tool to Predict Severe COVID-19 on Admission

Medicine

Published on 2021-02-182022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] 95% CI Accuracy Admission albumin AUROC body temperature characteristic China Clinical data collected Comorbidities coronavirus disease COVID-19 COVID-19 patient creatinine Critical cut-off value death diagnosed with COVID-19 Effectiveness eight enrolled evaluate group hospital independent risk factor Laboratory Logistic material Mortality mortality rate Neutrophil-to-lymphocyte ratio NLR nomogram Patient patients died patients with COVID-19 percentage Platelet predict prediction Predictive risk SARS-CoV-2 severe disease severe illness severity the patient total bilirubin variable were used with COVID-19
[DOI] 10.3389/fmed.2021.608107 PMC 바로가기 [Article Type] Medicine