Individual risk perception and empirical social structures shape the dynamics of infectious disease outbreaksResearch Article Published on 2022-02-162022-10-28 Journal: PLoS Computational Biology [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] absence accelerate addressed Affect affected change characterized Community Compliance Contact develop diffusion disease disease risk Effectiveness Epidemic epidemiological evaluate facial feature fixed fraction Government heterogeneity highlight Hospitalization Hospitalized individual individual level individuals infectious disease outbreak interaction pattern Mask mathematical Measures modulate outbreak performed risk Risk perception significantly social contact social distancing Spread Structure structures the disease the epidemic total population [DOI] 10.1371/journal.pcbi.1009760 PMC 바로가기 [Article Type] Research Article
Prevalence of COVID-19 Infection among Patients with Diabetes and Their Vaccination Coverage Status in Saudi Arabia: A Cross-Sectional Analysis from a Hospital-Based Diabetes RegistryArticle Published on 2022-02-162022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI 95% confidence interval accelerate adjusted odds ratio age Analysis city Confirmed COVID-19 infection Coverage COVID-19 COVID-19 infection COVID-19 vaccination determine diabete diabetes dose effective effort Elderly patient Factor female gender female patient groups higher risk hospital Infection infections likelihood male Mortality network pandemic Patient patients with diabete pharmacological treatments platform prevalence of COVID-19 Prince proportion registry representing retrieved Saudi Arabia Severe infection statistically significant difference status subgroup Sultan type 2 diabete vaccination vaccination rate Vaccine hesitancy Vaccines [DOI] 10.3390/vaccines10020310 PMC 바로가기 [Article Type] Article
COVID-19-Associated Encephalopathy—Case Series and Clinical ConsiderationsArticle Published on 2022-02-132022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] accelerate affected Case series Central nervous system change clinical CNS Cognitive function Course COVID-19 COVID-19 neurological complications covid-associated encephalopathy described diagnostic effective Encephalopathy feature functions help highlight Infection introduced majority manifestation neuroinfection neurological Patient patients progression SARS-COV-2 infection Sery similarity the disease the SARS-CoV-2 therapeutic process Treatment viral replication while [DOI] 10.3390/jcm11040981 PMC 바로가기 [Article Type] Article
Electrolyzed Water and Its Pharmacological Activities: A Mini-ReviewReview Published on 2022-02-112022-10-30 Journal: Molecules [Category] COVID-19, [키워드] accelerate Acidic Animal experiment Bacteria Bacterial blood sugar Care Chronic diseases clinical trial disinfecting agent Effect effective electrolyzed water Food industry growth Health in vitro in vivo Infectious diseases infectious viruses inhibit inhibitory effect multifunctional pathogenic bacteria positive Prevent promote provide Sodium chloride Viral diseases viruses water wound healing [DOI] 10.3390/molecules27041222 PMC 바로가기 [Article Type] Review
AutoPlate: Rapid Dose-Response Curve Analysis for Biological AssaysAutoPlate: 생물학적 분석을 위한 신속한 용량 반응 곡선 분석Immunology Published on 2022-02-102022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] accelerate analysed Analysis Biological biological assay COVID-19 Curve Data analysis develop Dose-response effective ELLA example immune correlate immunoassays IMPROVE Influenza Laboratory pseudotype pseudotype neutralization pseudovirus Rapid Safe SARS-C0V-2 SARS-CoV-2 Scientific community time-consuming Vaccine virus [DOI] 10.3389/fimmu.2021.681636 PMC 바로가기 [Article Type] Immunology
Reconstruction of the unbinding pathways of noncovalent SARS-CoV and SARS-CoV-2 3CLpro inhibitors using unbiased molecular dynamics simulations비공유 SARS-COV 및 SARS-COV-2 3CLPRO 억제제의 비 결합 경로의 재구성 편향되지 않은 분자 역학 시뮬레이션Research Article Published on 2022-02-092022-09-10 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 신약개발, 치료제, [키워드] 3CLpro accelerate addition binding binding pocket component COVID-19 pandemic drug drug design FDA approval help In silico method inhibit inhibitor Interaction Laboratory life cycle molecular molecular dynamics Molecular dynamics simulation molecular target pathway PDB Perspective protease protein-ligand interaction reconstruction Region Research residue residues SARS-CoV SARS-CoV-2 selected significantly these viruses Viral viral life cycle viruses water water molecule water molecules weakened [DOI] 10.1371/journal.pone.0263251 PMC 바로가기 [Article Type] Research Article
SASC: A simple approach to synthetic cohorts for generating longitudinal observational patient cohorts from COVID-19 clinical dataResearch article Published on 2022-02-092022-10-05 Journal: Patterns [Category] 임상, [키워드] accelerate Analysis applied approach boost caused Clinical data clinical trial clinical trials Cohort comparison coronavirus disease correlations COVID-19 COVID-19 patient effort generate Github Impact Mendeley Data pandemic Patient patient cohort provided real-world data researcher robust SASC statistical synthea variable VC virtual cohort [DOI] 10.1016/j.patter.2022.100453 [Article Type] Research article
Testing fractional doses of COVID-19 vaccines415 Published on 2022-02-072022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] accelerate approach approaches benefit booster Clinical data clinical evidence collected country COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines death deaths dosage dose dose stretching doses effective Effectiveness Efficacy epidemiological Evidence expected faster fractional dosing generate Government Health high correlation Infection less lower dose much lower Neutralizing antibody response Observational data occur pandemic potential benefit public health reduce researcher severe disease Significance Support switching Testing vaccination Vaccine Vaccines while [DOI] 10.1073/pnas.2116932119 PMC 바로가기 [Article Type] 415
The impact of COVID-19 on cancer care and oncology clinical research: an experts’ perspectiveCOVID-19가 암 치료 및 종양학 임상 연구에 미치는 영향: 전문가의 관점Review Published on 2022-02-012022-09-11 Journal: ESMO open [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] accelerate addition approach approaches Area article assessment Cancer cancer care Care catalyst Clinical research clinical trial clinical trials collaborative framework collected coronavirus coronavirus disease Coronavirus disease-19 COVID-19 COVID-19 pandemic described driving Efficacy endpoints Evidence faster Generalizability group Impact implementation IMPROVE include International IQVIA lead limit Local minority groups oncology optimization outcome pandemic Patient Perspective positive Real-world evidence Research risk Support Telemedicine timeline timelines Topic Treatment Trial [DOI] 10.1016/j.esmoop.2021.100339 PMC 바로가기 [Article Type] Review
Repurposing drugs for treatment of SARS-CoV-2 infection: computational design insights into mechanisms of actionSARS-COV-2 감염의 치료를위한 약물 용도 : 작용 메커니즘에 대한 전산 설계 통찰력Article Published on 2022-02-012022-08-31 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), MERS, SARS, 신약개발, 치료법, 치료제, [키워드] accelerate binding site Broad Institute caused ChEMBL Compound Computational drug Coronavirus infection COVID-19 COVID-19 pandemic database deaths determine develop drug Drug development Drug repurposing feature Features health emergency help human population identify in vitro in vitro data in vivo inhibit inhibitors inhibitors of SARS-CoV-2 Interaction life Ligand mechanism molecules negatively affected non-structural proteins Novel coronavirus Novel coronavirus infection nucleocapsid nucleocapsid protein pharmacophore predicted progressed Protein Protein binding Protein target protein targets repurposing Research SARS-CoV-2 SARS-CoV-2 genome screened the SARS-CoV-2 genome therapeutic intervention therapeutic interventions Treatment Viral Viral protein Viral proteins Virtual screening virus Visualisation was used [DOI] 10.1080/07391102.2020.1825232 PMC 바로가기 [Article Type] Article