Cellular immune response – Page 9 – Communicable Diseases Research

COVID-19 and solid organ transplantation: Finding the right balance

Review article

Published on 2022-07-012022-10-05
Journal: Transplantation Reviews [Category] COVID19(2023년), SARS, 치료제,

An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females

남성과 여성에서 ChAdOx1 nCoV-19(AZD1222) 백신에 대한 반응에 대한 탐색적 분석

Article

Published on 2022-07-012022-09-11
Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단,

[키워드] 95% CI Academy adjusted age and sex All participant All participants anti-SARS-CoV-2 anti-Spike IgG AstraZeneca AZD1222 both sexes Brazil Cellular immune response ChAdOx1 ChAdOx1 nCoV-19 Chinese clinical Clinical research clinical trials Coalition Council COVID-19 COVID-19 vaccine COVID-19 vaccines defined dose doses Efficacy endpoints Engineering enrolled Evidence evidence of Exploratory analysis fatigue female females Fever first dose Follow-up foundation funding generate GMR greater headache humoral immune responses immunogenicity immunogenicity data immunological individual Innovation interaction term ISRCTN Linear model linear models log-transformed logistic regression models majority male males Medical Science NAAT nCoV network neutralisation assay NIHR no evidence of nucleic acid nucleic acid amplification nucleic acid amplification test Oxford participant Participants primary endpoint randomised randomised controlled trial reaction reactogenicity receive Registered Regression model reported SARS-COV-2 infection Science Sex Sex-differences shown single-blind South spike IgG Standard dose statistically significant difference Superior symptomatic SARS-CoV-2 infection systemic reaction Telle the primary endpoint titre trial participants vaccination Vaccine vaccine efficacy Vaccines Valley Volunteer
[DOI] 10.1016/j.ebiom.2022.104128 PMC 바로가기 [Article Type] Article

Rational development of a combined mRNA vaccine against COVID-19 and influenza

Research

Published on 2022-07-012022-10-05
Journal: NPJ Vaccines [Category] 임상, 진단, 치료기술, 치료법,

Impact of disease-modifying therapies on humoral and cellular immune-responses following SARS-CoV-2 vaccination in MS patients

MS 환자에서 SARS-CoV-2 백신 접종 후 체액 및 세포 면역 반응에 대한 질병 수정 요법의 영향

Article

Published on 2022-07-012022-09-12
Journal: Clinical and translational science [Category] COVID19(2023년), MERS, SARS, 진단,

Antibody and cellular immune responses following dual COVID-19 vaccination within infection-naive residents of long-term care facilities: an observational cohort study

Observational Study

Published on 2022-07-012022-10-05
Journal: The Lancet. Healthy longevity [Category] COVID19(2023년), SARS, 변종, 임상, 진단,

[키워드] age antibody Antibody Response binding blood sample booster vaccination Care CD4 T-cell Cellular immune response cellular response Clinical outcome Comorbidity COVID-19 COVID-19 vaccination COVID-19 vaccine CXCL10 production Department EDTA eligible exclusion criteria Factors for inclusion frailty functional groups humoral IFN-γ IL-2 immune dysregulation immune protection immune response Impaired individual Infection IQR median median age neutralisation Observational cohort study Older participant Post-vaccine quantified response risk factor Sample SARS-CoV-2 SARS-COV-2 infection second vaccination SFU significantly staff stratified T-cell Response TNFα vaccination vaccine doses variant spike was reduced were assessed
[DOI] 10.1016/S2666-7568(22)00118-0 PMC 바로가기 [Article Type] Observational Study

Cellular and Humoral Immune Response to a Third Dose of BNT162b2 COVID-19 Vaccine – A Prospective Observational Study

BNT162b2 COVID-19 백신의 3차 접종에 대한 세포 및 체액 면역 반응 - 전향적 관찰 연구

Observational Study

Published on 2022-07-012022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술,

[키워드] addition administration All participant All participants anti-SARS-CoV-2 antibody binding binding antibody blood sample Blood samples BNT162b2 booster booster dose cellular Cellular immune response Combination COVID-19 detectable dose evaluate health-care humoral humoral and cellular immunity Humoral immunity immune response Immunity immunological infection rate infection rates interferon Interferon-gamma median Neutralizing antibodies neutralizing antibody observational study of BNT162b2 participant peptide peptides prime-boost regimen Prospective prospective observational study protocols provided quantitative assay questionnaire Questionnaires real-world data response SARS-CoV-2 second dose Seroprevalence significant increase significantly third dose vaccination Vaccine was measured were measured
[DOI] 10.3389/fimmu.2022.896151 PMC 바로가기 [Article Type] Observational Study

COVID-19: Omicron – the latest, the least virulent, but probably not the last variant of concern of SARS-CoV-2

COVID-19: 오미크론 - 최신, 가장 덜 독성이지만 SARS-CoV-2의 우려의 마지막 변종은 아닐 것입니다.

Review

Published on 2022-07-012022-09-11
Journal: Microbial Biotechnology [Category] COVID19(2023년), SARS, 변종,

[키워드] affected Antibody Response Antiviral booster breadth cell entry Cellular immune response convalescent patient Convalescent patients COVID-19 pandemic Delta demonstrated dominant Endocytic pathway experiment explain fusion hamsters Immune escape immunization Infection intrinsic less Lineage Lung function mainstream mice monoclonal antibodies mutated Mutation neutralization omicron Omicron variant plasma membrane population immunity preserved question raising Replication respiratory tract SARS-CoV-2 SARS-CoV-2 strain serum antibodies serum antibody Severe infection severe infections South Africa Spike protein the spike protein therapeutic titre trajectory Transmission vaccinee vaccinees variant virulence virulent VoC widespread
[DOI] 10.1111/1751-7915.14064 PMC 바로가기 [Article Type] Review

Prevalence of COVID-19-associated symptoms during acute infection in relation to SARS-CoV-2-directed humoral and cellular immune responses in a mild-diseased convalescent cohort

경증 회복기 코호트에서 SARS-CoV-2 유도 체액 및 세포 면역 반응과 관련하여 급성 감염 중 COVID-19 관련 증상의 유병률

Article

Published on 2022-07-012022-09-12
Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] acute infection antibody antiviral immunity association Cellular immune response cellular immune responses Cohort convalescent convalescent individual correlation cough COVID-19 COVID-19 symptom COVID-19 symptoms disease severity effective eight evaluated humoral humoral immune response humoral immune responses IgG immune immune response intensities intensity Loss of Smell majority no difference polymerase chain positive Prevalence Prevent questionnaire recent reduced SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2-specific T cell Serum level severe symptom severity shown Symptom symptom severity Symptoms T cell response T cells virus clearance were assessed
[DOI] 10.1016/j.ijid.2022.04.019 PMC 바로가기 [Article Type] Article

Immunogenicity of the third and fourth BNT162b2 mRNA COVID-19 boosters and factors associated with immune response in patients with SLE and rheumatoid arthritis

세 번째 및 네 번째 BNT162b2 mRNA COVID-19 부스터 및 SLE 및 류마티스 관절염 환자의 면역 반응과 관련된 인자의 면역원성

Article

Published on 2022-07-012022-09-11
Journal: Lupus science & medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] adenoviral vector Administered anti-RBD Anti-RBD IgG Arthritis benefit BNT162b2 BNT162b2 mRNA booster booster dose booster vaccination cellular Cellular immune response COVID-19 domain enrolled evaluate Factor heterogenous humoral Humoral response IgG immune response immunogenicity immunosuppressive inactivated Inactivated vaccine initial Lupus lupus erythematosus Lupus Erythematosus, Systemic mRNA vaccines Neutralising activity occurred omicron Omicron variant Patient positive raised RBD RBD IgG registration number rheumatoid arthritis significantly SLE systemic titre vaccination Vaccine variant was done were given
[DOI] 10.1136/lupus-2022-000726 PMC 바로가기 [Article Type] Article

Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum

폴리(I:C) 플러스 명반과 관련된 SARS-CoV-2 삼량체 스파이크 단백질의 면역원성

Article

Published on 2022-06-302022-09-12
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] addition adjuvant adjuvants alum antibody B cell BALF Bronchoalveolar lavage fluid CD4 CD8 Cellular immune response Combination domain ELISA enzyme evaluated expected germinal centers IgA IgG IgG anti-spike antibody IgG1 IgG2a immunization immunogenicity immunosorbent in vitro inactivated induce intradermal route lung Lung inflammation mice Neutralization assay Neutralizing titer neutralizing titers neutrophil recruitment New Poly (I:C) poly(I:C positive prefusion produced producing Protein RBD reduced reduction in required SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 virus serum spike Spike protein Subtypes supported T cell Th1 Th1 phenotype the SARS-CoV-2 trimeric vaccination Vaccination strategy Vaccine
[DOI] 10.3389/fimmu.2022.884760 PMC 바로가기 [Article Type] Article