Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy
Oct1/Pou2f1은 결장 재생에 선택적으로 필요하며 결장 악성 종양을 조절합니다.
Research Article
[키워드] allele
blocked
Cancer
Cell
Characteristics
ChIPseq
Colon
Colon cancer
colon carcinoma
Colorectal
Colorectal cancer
damage
death
deleted
Deletion
determine
dextran
diagnosed
differentially expressed
differentially expressed gene
Differentially expressed genes
disease
driven by
Effect
etiology
expressed
Factor
gastrointestinal tract
Gene Expression
gene target
Gut
gut stem cell
homeostasis
identify
in vitro
in vivo
incidence
intestinal stem cell
Intestinal stem cells
maintain
maintenance
malignancy
mechanism
metabolism
mitotic
Mortality
Organoid
organoids
outcome
outcomes
overlap
passage
pathophysiology
Patient
Physiology
Pou2f1
preserved
proceed
promote
protein level
regulate
required
significantly
sodium
sodium sulfate
stability
stem cell
stem cells
Stress
stress response
sulfate
Suppressor gene
target gene
Target genes
targets
The United States
transcription factor
Treatment
Tumor
tumor suppressor
tumor suppressor gene
United States
[DOI] 10.1371/journal.pgen.1007687 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1007687 PMC 바로가기 [Article Type] Research Article