Hepatitis B virus activity is not associated with degree of liver steatosis in patients with hepatitis B-related chronic liver diseaseComment Published on 2020-06-012023-06-11 Journal: Liver international : official journal of the Inte [Category] B형 간염, [키워드] Fatty liver hepatitis B Non-alcoholic fatty liver disease [DOI] 10.1111/liv.14344 [Article Type] Comment
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver diseaseMitochondrial Amidoxime Reducing Component 1 유전자의 missense 변이와 간 질환에 대한 보호Research Article Published on 2020-04-132022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Alanine Alanine transaminase alkaline phosphatase allele Blood blood cholesterol level Blood level blood levels carrier carriers cause of death cholesterol cirrhosis coding variant cohorts component computed tomographic Control death deficiency eight enzyme exhibit fat Fatty liver Genetic genetic finding genetic findings hepatic fat homozygous identify individual LDL cholesterol liver Liver disease liver enzyme loss-of-function MARC1 Missense missense variant mitochondrial phosphatase potential therapeutic target predicted PROTECT reduced reduced risk Total cholesterol variant [DOI] 10.1371/journal.pgen.1008629 PMC 바로가기 [Article Type] Research Article
[Characteristics, diagnostic and therapeutic strategies for chronic hepatitis B combined with non-alcoholic fatty liver disease]Article Published on 2020-03-202023-06-12 Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese [Category] B형 간염, [키워드] Diagnosis Fatty liver Hepatitis B virus therapy [DOI] 10.3760/cma.j.cn501113-20200107-00008
Causal relationships between obesity and the leading causes of death in women and men비만과 여성과 남성의 주요 사망 원인 사이의 인과 관계Research Article Published on 2019-10-242022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adjusted Affect Analysis association blood pressure BMI body mass body mass index cardiometabolic disease cardiometabolic diseases causal relationship causal relationships cause Chronic kidney disease chronic liver disease chronic obstructive chronic obstructive pulmonary disease chronic renal failure Cochran’s Q-test Coronary artery Coronary artery disease death diabete diabetes Diabetes Mellitus disease disease risk downstream Effect etiological Fatty liver fatty liver disease genetic data genetic risk score genetic variants glycemic GRS heart disease higher risk implicated implication increase increased risk indicate instrumental variable instrumental variables investigated involved Kidney disease lung cancer majority mediators men men and women mendelian randomization Mortality Non-alcoholic fatty liver disease non-communicable diseases obesity obstructive pulmonary disease preventative measure public health pulmonary disease renal renal failure risk smoking Still stroke traits type 2 diabete type 2 diabetes UK biobank waist waist-hip ratio Waist-hip-ratio WHR women [DOI] 10.1371/journal.pgen.1008405 PMC 바로가기 [Article Type] Research Article
Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis비알코올성 지방간염에서 미리오신의 치료 효과 및 자가포식 조절Research Published on 2019-10-212022-09-06 Journal: Lipids in Health and Disease [Category] B형 간염, Communicable Disease, [키워드] Acox-2 active CHB administration Adults alternate days analyzed animal model autophagy autophagy function autophagy marker autophagy markers ballooning blockade body weight ceramide ceramide signaling Ceramides change CHB chronic hepatitis Chronic Hepatitis B Control Cpt-1α de novo synthesis disease dyslipidemia elevated expression pattern Fabp1 fatty Fatty acid fatty acid metabolism Fatty liver fatty liver disease healthy hepatic autophagy function HepG2 cell HepG2 cells HFD-induced NASH High fat diet incubated Lipid accumulation liver Liver Biopsy liver biopsy-proven patient liver biopsy-proven patients Liver histology liver pathology lobular inflammation mechanisms metabolism myriocin NAFLD NASH NASH patient NASH patients Non-alcoholic fatty liver disease non-NASH patients nonalcoholic fatty liver Nonalcoholic Fatty Liver Disease oral administration Pathogenesis pathogenic Patient PPARα profiles qPCR qPCR analysis randomly divided RATs Registered Registration Regulation Regulatory restored Result reversed screened serum transaminase serum transaminases significantly significantly increased sphingolipid steatohepatitis steatosis subject three groups Treatment were measured [DOI] 10.1186/s12944-019-1118-0 PMC 바로가기 [Article Type] Research
Influence of hepatic steatosis on the outcomes of patients with chronic hepatitis B treated with entecavir and tenofovirArticle Published on 2019-09-012023-06-18 Journal: Clinical and molecular hepatology [Category] B형 간염, Fulltext, [키워드] antiviral agent Fatty liver Hepatitis B, chronic [DOI] 10.3350/cmh.2018.0054 PMC 바로가기
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE NetworkResearch Article Published on 2019-07-172024-09-02 Journal: BMC Medicine [Category] 대상포진, [키워드] Fatty liver Genetic polymorphism GWAS NAFLD PheWAS polygenic risk score [DOI] 10.1186/s12916-019-1364-z PMC 바로가기 [Article Type] Research Article
Fibrosis evolution in chronic hepatitis B e antigen-negative patients across a 10-year intervalArticle Published on 2019-07-012023-06-18 Journal: Journal of viral hepatitis [Category] B형 간염, [키워드] Fatty liver hepatitis B Liver fibrosis metabolic syndrome [DOI] 10.1111/jvh.13095
Hepatobiliary and pancreatic manifestations in inflammatory bowel diseases: a referral center studyResearch Article Published on 2019-04-032023-05-23 Journal: BMC Gastroenterology [Category] B형 간염, Fulltext, [키워드] acute pancreatitis Fatty liver Hepatobiliary manifestations hepatotoxicity immunomodulators Inflammatory bowel disease Pancreatic manifestations [DOI] 10.1186/s12876-019-0967-3 PMC 바로가기 [Article Type] Research Article
Association between hepatic steatosis and the development of hepatocellular carcinoma in patients with chronic hepatitis BArticle Published on 2019-03-012023-06-18 Journal: Clinical and molecular hepatology [Category] B형 간염, Fulltext, [키워드] Fatty liver Hepatitis B virus Liver cancer metabolic syndrome Nonalcoholic fatty liver disease (NAFLD). [DOI] 10.3350/cmh.2018.0040 PMC 바로가기