Infections with the SARS-CoV-2 Delta variant exhibit fourfold increased viral loads in the upper airways compared to Alpha or non-variants of concernSARS-CoV-2 Delta 변이체 감염은 우려되는 알파 또는 비 변이체에 비해 상기도에서 4배 증가된 바이러스 부하를 나타냅니다.Article Published on 2022-08-172022-09-11 Journal: Scientific Reports [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age all age group all age groups Alpha Alpha variant B.1.1.7 B.1.617.2 coronavirus Delta delta variant dominant Evidence evidenced genomic Genomic surveillance group groups in viral no difference Older age other variants reported respiratory sample Respiratory samples Sample size SARS-CoV-2 severe acute respiratory syndrome Coronavirus Sex significantly lower suggested Surveillance the SARS-CoV-2 Transmissibility upper airway vaccination variant variants Viral load viral loads Wuhan strain [DOI] 10.1038/s41598-022-18279-5 PMC 바로가기 [Article Type] Article
Advancing Precision Vaccinology by Molecular and Genomic Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 in Germany, 20212021년 독일에서 중증 급성 호흡기 증후군 코로나바이러스 2의 분자 및 게놈 감시를 통한 정밀 백신학 발전Article Published on 2022-08-152022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 유전자 메커니즘, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Advancing Alpha variant Analysis approach Beta collected complement Comprehensive contributed coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 dataset deceleration Delta wave Effectiveness effort estimate Evolution expansion facilitated Genetic genomic genomic sequencing Genomic surveillance Germany GISAID immune evasion in vitro incidence incidence estimation indicated Laboratory molecular molecular surveillance Multiple multiple mutations Mutation National neutralization assays observation period pathogen pathogen genomics Phylogenetic analysis powerful tool Precision Public public health Randomly respiratory resulting Robert Koch SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 genomic surveillance sequence sequenced sample Spread Surveillance the SARS-CoV-2 undergo vaccination Vaccination strategies Vaccination strategy Vaccine variant variant of concern variants of concern virus whole-genome sequencing [DOI] 10.1093/cid/ciac399 PMC 바로가기 [Article Type] Article
Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients향상된 SARS-CoV-2 시퀀싱 감시를 통해 감염된 환자의 새로운 변이체 및 서명 식별 가능Article Published on 2022-08-122022-09-11 Journal: Genome Medicine [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis applied approach Automation B.1 Campania cohorts of patients collected coronavirus correlated COVID-19 pandemic Disease progression Efficacy gain-of-function gene expression signature generate genetic variability Genome genomic Genomic surveillance highest Host host gene expression identify immune protection Improved increase in infected patient Infection Italy lab limit Metadata MONITOR Mutation nasal swab nasal swabs pandemic Patient premises principle producing prognostic biomarker Prognostic biomarkers reconstructed respiratory epithelium reverse transcribed RNA Sample SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-COV-2 infection SARS-CoV-2 sequencing scrutiny sequence sequenced sequences severe acute respiratory syndrome Coronavirus Spread Surveillance Transcriptome Treatment upper respiratory Vaccination strategies Vaccination strategy Variability variant variants of concern viral genome Viral genome sequencing viral genomes Viral load viral variant virus VoC was performed [DOI] 10.1186/s13073-022-01098-8 PMC 바로가기 [Article Type] Article
Genomic surveillance of SARS-CoV-2 in Puerto Rico enabled early detection and tracking of variants Research Published on 2022-08-112022-10-05 Journal: Communications Medicine [Category] 변종, 치료기술, [키워드] agency Analysis approach cause circulation competing conducted COVID-19 COVID-19 case COVID-19 pandemic Critical Epidemic event genomic Genomic surveillance Health highlight Lineage Local Molecular epidemiology phylogenetic inference predominant public health Public health responses replaced Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomic surveillance SARS-CoV-2 variant sequenced Spread spread to study period Surveillance The United States variant virus [DOI] 10.1038/s43856-022-00168-7 [Article Type] Research
Genomic surveillance, evolution and global transmission of SARS-CoV-2 during 2019-20222019-2022년 동안 SARS-CoV-2의 게놈 감시, 진화 및 전 세계 전파Article Published on 2022-08-012022-09-11 Journal: PLoS ONE [Category] SARS, 변종, 유전자 메커니즘, [키워드] analyzed Beta conducted correlation COVID-19 pandemic Delta died E484K Evolution Evolutionary rate fatality followed by Frequency Gamma genomic genomic data Genomic surveillance growth growth rate Health help information L452R likelihood Multiple Multiple sequence alignment Mutation N439K N501Y omicron outcome pandemic Point mutation point mutations predominant prevalent reduce SARS-COV-2 infection sequence Sequence alignment Spike protein Substitution Surveillance transmission of SARS-CoV-2 Vaccine variant variants VoC [DOI] 10.1371/journal.pone.0271074 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Omicron sublineage BA.2 replaces BA.1.1: Genomic surveillance in Japan from September 2021 to March 2022SARS-CoV-2 Omicron 하위 계통 BA.2가 BA.1.1을 대체: 2021년 9월부터 2022년 3월까지 일본의 게놈 감시Comment Published on 2022-08-012022-09-11 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Abstract BA.2 Genomic surveillance Japan omicron Omicron, BA.1 SARS-CoV-2 variant variant of concern [DOI] 10.1016/j.jinf.2022.04.040 PMC 바로가기 [Article Type] Comment
Evaluation of EPISEQ SARS-CoV-2 and a Fully Integrated Application to Identify SARS-CoV-2 Variants from Several Next-Generation Sequencing ApproachesEPISEQ SARS-CoV-2 평가 및 여러 차세대 시퀀싱 접근 방식에서 SARS-CoV-2 변이체 식별을 위한 완전 통합 애플리케이션Article Published on 2022-07-292022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] accelerate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis application approach bioinformatics clade Concordance consensus sequence coronavirus Coverage effort Genome genome assembly genomic Genomic surveillance handling Laboratory Lineage Mutation mutation screening Next-generation sequencing Nextstrain Nextstrain clade NGS pango lineage platform reagents reference genome SARS-CoV-2 SARS-CoV-2 mutation Sequencing sequencing protocol severe acute respiratory syndrome Coronavirus spike mutation Support Surveillance variant variant identification. variety whole-genome sequencing [DOI] 10.3390/v14081674 PMC 바로가기 [Article Type] Article
SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.22021년 9월부터 11월까지 영국의 SARS-CoV-2 계보 역학: Delta 하위 계통의 높은 다양성과 AY.4.2의 전파 가능성 증가Article Published on 2022-07-272022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI assessment Clustering Community community transmission country COVID-19 COVID-19 symptom Delta delta variant endemicity England exhibiting genetic diversity genomic data Genomic surveillance greater immune Immune escape Immunity increases in individual introduced less Lineage lineages Mutation mutation rate natural infection no symptom no symptoms nose swab Phylogenetic relationship positive individuals Predictive prevalent lineage proportion provided random reduced reduction in Region reported Reproduction number RT-PCR testing SARS-CoV-2 SARS-CoV-2 lineage South study period surveillance data symptom status symptomatic individuals Transmissibility Transmission advantage unique vaccination variant virus [DOI] 10.1186/s12879-022-07628-4 PMC 바로가기 [Article Type] Article
A comparison of high-throughput SARS-CoV-2 sequencing methods from nasopharyngeal samples비인두 샘플의 고처리량 SARS-CoV-2 시퀀싱 방법 비교Article Published on 2022-07-222022-09-11 Journal: Scientific Reports [Category] Coronavirus, COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, 치료제, [키워드] absence acute respiratory syndrome coronavirus amplification applied approach caused coronavirus 2 Coverage COVID-19 pandemic COVIDSeq detect epidemiological genomic Genomic surveillance Healthcare system Healthcare systems infected individuals limitation multiplex nasopharyngeal sample Nasopharyngeal samples Nasopharyngeal swab nasopharyngeal swabs Next-generation sequencing pandemic of COVID-19 public health respiratory risk SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequencing SARS-CoV-2 sequencing severe acute respiratory syndrome coronavirus 2 successive wave supply shortage Supply shortages Surveillance tested Transmissibility Treatment Vaccine variant variants virulence was obtained whole genome [DOI] 10.1038/s41598-022-16549-w PMC 바로가기 [Article Type] Article
Genomic surveillance of SARS-CoV-2 in US military compounds in Afghanistan reveals multiple introductions and outbreaks of Alpha and Delta variants아프가니스탄의 미군 화합물에서 SARS-CoV-2의 게놈 감시는 알파 및 델타 변이체의 다중 도입 및 발생을 보여줍니다Article Published on 2022-07-152022-09-11 Journal: BMC Genomics [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Afghanistan alpha and delta variants analyzed base collected Compound compounds Delta delta variant Epidemiology genomic Genomic surveillance independent military occur occurred outbreak Outbreaks phylogenetic analyses Phylogenetic analysis reveal SARS-CoV-2 SARS-CoV-2 variants Sequencing Spread Surveillance sustained variant variants virus [DOI] 10.1186/s12864-022-08757-5 PMC 바로가기 [Article Type] Article