SARS-CoV-2, ACE2, and Hydroxychloroquine: Cardiovascular Complications, Therapeutics, and Clinical Readouts in the Current SettingsReview Published on 2020-07-072022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome Analysis angiotensin-converting enzyme 2 benefit cardiovascular cardiovascular complication cardiovascular disease (CVD) Cardiovascular function cardiovascular system caused clinical clinical settings clinics coronavirus coronavirus disease COVID-19 Critical current drug Efficacy functional global healthcare HCQ Hydroxychloroquine immunomodulatory activities Intervention key consideration physiological provide recommendation report SARS-CoV-2 SARS-CoV-2 replication setting target receptor targets Therapeutics while widespread [DOI] 10.3390/pathogens9070546 PMC 바로가기 [Article Type] Review
Ethics for surgeons during the COVID-19 pandemic, review articleReview Article Published on 2020-06-082022-10-28 Journal: Annals of Medicine and Surgery [Category] COVID-19, [키워드] applied Autonomy Care conducted COVID-19 COVID-19 pandemic Effect effort Ethics global healthcare help Justice outcome pandemic Patient patients predict professionalism public health surgeon Surgeons surgery surgical Treatment [DOI] 10.1016/j.amsu.2020.06.003 PMC 바로가기 [Article Type] Review Article
The role of the orthopaedic surgeon in the COVID-19 era: cautions and perspectivesReview Paper Published on 2020-05-272022-10-30 Journal: Journal of Experimental Orthopaedics [Category] COVID-19, [키워드] activity addition affected Care consequence Contact coronavirus coronavirus disease COVID-19 COVID-19 pandemic COVID-19 patient education Elective surgery exceptional Frame global healthcare Healthcare provider hospital Implications indication Infection Inpatient International Intervention Isolation management National orthopaedic surgery other diseases outpatients pandemic Particular Patient patients Perspective PPE recruited reduce resulting Safe SARS-CoV-2 significantly Spread surgeon surgical Surgical algorithm Surgical indication Telemedicine Treatment urgency [DOI] 10.1186/s40634-020-00255-5 PMC 바로가기 [Article Type] Review Paper
Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 InfectionImmunology Published on 2020-05-122022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress addition ARDS Care caused clinical trial combined treatment Complication complications coronavirus Coronavirus infection COVID-19 Cytokine storm direct infection Effect global healthcare global pandemic Guidance hematopathologic effect Host immune response immune Immune cell immune response immune responses immune therapy infection mechanism infection-induced lymphopenia Invasion killing mechanism medication MERS-CoV molecular mechanism Novel coronavirus outbreak Patient Potential treatment Prevent Prophylactic pulmonary fibrosis reduce Replication required response responses resulting risk SARS-CoV SARS-CoV-2 SARS-CoV-2 infected patient Severe case severe respiratory syndrome Spread syndrome the disease Therapeutic approach therapeutic approaches therapy Vaccine Vaccine development Wuhan, China [DOI] 10.3389/fimmu.2020.01022 PMC 바로가기 [Article Type] Immunology
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach새로운 MMP12 유전자좌는 게놈 전체 발병 연령 정보 접근 방식을 사용하여 대동맥 죽상경화성 뇌졸중과 연관됩니다Research Article Published on 2014-07-312022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] (atherosclerosis) affected affection age analyses Analysis approach arteries Artery association associations Atherosclerosis atherosclerotic carotid carotid artery chromosome chromosome 11 Conditioning controls covariate demonstrated detect disease disease risk European evaluate Evidence evidence of examined explain Fold change fraction genetic association genetic associations genetic component Genetic predisposition Genetic variant Genome-wide association studies global healthcare GWAS heterogeneity identify IMPROVE increased risk independent information Informed investigated ischaemic stroke large artery lead loci locus Meta-analysis MMP12 mRNA expression novel novel association novel associations overexpressed performed phenotype phenotypic plaque plaques power prevalence rate prevalence rates Regression regression analysis Replication risk significantly small vessel SNP association SNP associations stroke subtype Subtypes the disease variant variants was performed [DOI] 10.1371/journal.pgen.1004469 PMC 바로가기 [Article Type] Research Article