highly pathogenic

[키워드] ACE2 ACE2, angiotensin converting enzyme 2 addition addressed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Antigen binding C-type lectins Cat B/L, cathepsin B/L cathepsin cathepsin B Cathepsins CD147 CD147, cluster of differentiation 147 Cell cofactor cofactors complex coronavirus Cyp A/B, cyclophilin A/B determine disrupt endocytosis ENhance entry cofactor examined Factor Factors feature HCoV, human coronavirus heparan sulfate highlighting highly pathogenic Host host cell host cell membrane host protease host proteases HSPG, heparin sulfate proteoglycan human coronaviruses human population identify IFITM, interferon-induced transmembrane proteins interferon ISG, Interferon-stimulated gene locus Ly6E, lymphocyte antigen 6E lymphocyte mechanism membrane fusion MERS-CoV, Middle East respiratory syndrome coronavirus MHV, mouse hepatitis virus neuropilin Neuropilin-1 NRP-1, neuropilin-1 pathogenicity Phosphatidylserine plasma membrane protease proteoglycans PS, phosphatidylserine RBD, receptor binding domain recent receptor receptors RNA virus role SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 pandemic SARS-CoV-2 receptor SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SARS-CoV, severe acute respiratory syndrome coronavirus Serine serine 2 sialic acids Spike protein sulfate the cell the SARS-CoV-2 TIM-1, T-cell immunoglobulin and mucin domain 1 TMPRSS2 TMPRSS2, transmembrane protease, serine 2 transmembrane transmembrane protease serine 2 transmembrane protein unique Viral viral envelope viral spike protein virus entry virus receptor zoonotic transmission
[DOI] 10.1016/j.jbc.2021.100847 PMC 바로가기 [Article Type] Review