Newer Horizon of Mesenchymal Stem Cell–Based Therapy in the Management of SARS-CoV-2–Associated Mucormycosis: A Safe Hope for Future MedicineMicrobiology Published on 2021-10-112022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] addition affected approach boost chemotactic clinical trial Combination Complication COVID-19 Cytokine storm Diabetes Mellitus Diabetic drug early diagnosis Factor Future growth help Hope Horizon hyphae Immunity Immunocompromised Immunocompromised patient immunomodulation immunomodulatory innate immune response life-threatening management mechanism Medicine Mesenchymal stem cells MSC MSCs Mucorale Mucormycosis Neurological complications outcomes overcome Patient Prolonged Proteins regenerative reported responsible SARS-CoV-2 SARS-CoV-2–infected patient STEM stem cell therapy Treatment use of steroids variety [DOI] 10.3389/fmicb.2021.738983 PMC 바로가기 [Article Type] Microbiology
Interferon gamma runs interference on persistent COVID-19인터페론 감마는 지속적인 COVID-19에 대한 간섭을 실행합니다Comment Published on 2021-10-082022-09-11 Journal: Med (New York, N.Y.) [Category] SARS, 변종, [키워드] approach COVID-19 disease FIVE IFNγ Immunocompromised patient infection with SARS-CoV-2 interferon gamma Precision Stage stages treated viral variant [DOI] 10.1016/j.medj.2021.09.004 PMC 바로가기 [Article Type] Comment
Sensitivity of two SARS-CoV-2 variants with spike protein mutations to neutralising antibodies중화 항체에 대한 스파이크 단백질 돌연변이를 갖는 2 개의 SARS-COV-2 변이체의 민감도Original Paper Published on 2021-10-042022-09-01 Journal: Virus Genes [Category] MERS, SARS, 변종, 진단, [키워드] accumulate addition Affect antibody antibody treatment assigned B.1.351 Complete COVID-19 distribution Donor Efficacy elicit escape mutation evaluated greater humoral immune response Immune escape Immunocompromised patient infected patient infected with SARS-CoV-2 insensitivity Lineage monoclonal mutated variant Mutation Mutation E484K mutations neutralisation neutralising Neutralising activity Neutralising Antibodies neutralising antibody Patient patients Prolonged infection reduction in representing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variant sensitivity serum sample serum samples Spike protein the spike protein Therapeutics Vaccine variant variants variants of concern virus virus variant wild-type wild-type SARS-CoV-2 [DOI] 10.1007/s11262-021-01871-8 PMC 바로가기 [Article Type] Original Paper
SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USAHIV/AIDS 환자의 SARS-CoV-2 중화 저항성 돌연변이, 캘리포니아, 미국Research Letter Published on 2021-10-012022-09-10 Journal: Emerging Infectious Diseases [Category] 변종, [키워드] 2019 novel coronavirus disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 AIDS antimicrobial resistance California coronavirus coronavirus disease Coronaviruses COVID-19 HIV/AIDS Immunocompromised Immunocompromised patient Immunocompromised patients Infection mutations N terminal domain neutralization Patient Receptor binding domain resistance respiratory respiratory infections SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 United States USA variant viral evolution virus viruses zoonoses [DOI] 10.3201/eid2710.211461 PMC 바로가기 [Article Type] Research Letter
COVID-19-related outcomes in immunocompromised patients: A nationwide study in KoreaResearch Article Published on 2021-10-012022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval adjusted adjusted odds ratio Analysis approach baseline baseline characteristics calculated CIs Comorbidities Comorbidity coronavirus disease Corticosteroid COVID-19 COVID-19 patient determine Diagnosis had more higher risk HIV/AIDS identify Immunocompromised Immunocompromised patient immunocompromised status Immunosuppressant in-hospital mortality in-hospital mortality rate increased risk malignancy Mortality multivariable logistic regression Older organ outcome Probability Result risk risk factor severe COVID-19 significantly higher significantly increased Treatment vulnerable patients Weighting with COVID-19 [DOI] 10.1371/journal.pone.0257641 PMC 바로가기 [Article Type] Research Article
A unique case of Miller Fisher-Guillain-Barré overlap syndrome in a liver transplant recipient간 이식 환자의 Miller Fisher-Guillain-Barré 중첩 증후군의 독특한 사례Case Reports Published on 2021-09-222022-09-10 Journal: Journal of Neurovirology [Category] MERS, SARS, 변종, [키워드] Acute respiratory failure Chain Reaction Complication COVID-19 COVID-19 infection cranial Cranial nerve demonstrated descending Descending paralysis diagnosed Diagnosis Diaphragm electromyography facial Fisher Fisher syndrome Guillain-Barré syndrome Guillain-barrè syndrome highlight Immunocompromised patient Infection liver liver transplant Liver transplantation Miller Miller fisher syndrome Nasopharyngeal swab nasopharyngeal swabs Nerve conduction nerve conduction study neurologic Neurological complication Neurological complications occur ophthalmoplegia overlap overlap syndrome paralysis patients plasma plasma exchange polymerase chain polymerase chain reaction Polyneuropathy positive predominant progressed quadriparesis recipients Respiratory failure SARS-CoV-2 IgG serology solid organ solid organ transplant Symptom syndrome thought Treatment unique variant [DOI] 10.1007/s13365-021-01015-6 PMC 바로가기 [Article Type] Case Reports
Outpatient Management of COVID-19 With Monoclonal Antibody Therapy in a Young Renal Transplant PatientInternal Medicine Published on 2021-09-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] available data baseline Care complex coronavirus disease cough COVID-19 high mortality rate highlight Hospitalization ICU Immunocompromised patient Immunosuppression immunosuppressive increased risk infectious complication mAb male mild case monoclonal antibodies monoclonal antibody monotherapy Mortality Outpatient Patient positive receiving recipient regimen regimens renal Renal transplant significantly lower solid organ transplant symptomatic tested therapy Transplant treated [DOI] 10.7759/cureus.17672 PMC 바로가기 [Article Type] Internal Medicine
Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study영국 런던의 신종 SARS-CoV-2 B.1.1.7 계통의 게놈 특성 및 임상 효과: 전체 게놈 시퀀싱 및 병원 기반 코호트 연구Article Published on 2021-09-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] SARS, 변종, 치료기술, [키워드] adjusted age analysed Analysis association B.1.1.7 B.1.1.7 variant Characteristics Clinical effect Clinical severity Cohort cohort study collected college Comorbidities Council Cycle threshold value death defined emergence Engineering epitope Epitopes Ethnicity Evidence evidence of genomic genomic read hospital hospitalised identify Immunocompromised patient Immunocompromised patients inclusion criteria Infection Lineage London mass vaccination monoclonal antibodies Mutation mutations NHS NIHR no evidence of Ordinal Scale Patient patients PCR PCR cycle Poisson regression model Poisson regression models positive Positive test Prevalence raise Remdesivir SARS-CoV-2 SARS-CoV-2 B.1.1.7 Science sequenced Sequencing severe disease Sex specific mutation specific mutations Spike protein Symptom the spike protein the WHO threshold value Transmissibility Trust university vaccination variant variants Viral load Virological virus load VoC WHO ordinal scale whole-genome sequencing [DOI] 10.1016/S1473-3099(21)00170-5 PMC 바로가기 [Article Type] Article
Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland면역 저하 환자, 아일랜드에서 SARS-CoV-2 바이러스의 게놈 진화Research Letter Published on 2021-09-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] 2019 novel coronavirus disease acute respiratory syndrome B-cell therapy coronavirus coronavirus disease COVID-19 Evolution examined Genetic variation genomic genomic sequencing Immunocompromised Immunocompromised patient Immunocompromised patients Infection Ireland lead Mutation new virus Prolonged Prolonged infection respiratory respiratory infections SARS-CoV-2 Sequencing severe acute respiratory syndrome coronavirus 2 superinfection variants virus Virus evolution viruses zoonoses [DOI] 10.3201/eid2709.211159 PMC 바로가기 [Article Type] Research Letter
Bamlanivimab as monotherapy in two immunocompromised patients with COVID-192명의 면역저하 코로나19 환자에서 단독요법으로 밤라니비맙(Bamlanivimab)Article Published on 2021-09-012022-09-12 Journal: The Lancet. Microbe [Category] Fulltext, SARS, 진단, [키워드] bamlanivimab Immunocompromised patient monotherapy with COVID-19 [DOI] 10.1016/S2666-5247(21)00189-0 PMC 바로가기 [Article Type] Article