On the temporal spreading of the SARS-CoV-2Research Article Published on 2020-10-292022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Activation analysed changes in Characteristics complex Contagion country Course highlight identify information latency Mathematical modelling Measures outbreak pandemic physical progression SARS-CoV-2 virus Stage the SARS-CoV-2 virus [DOI] 10.1371/journal.pone.0240777 PMC 바로가기 [Article Type] Research Article
Is Covid-19 lockdown related to an increase of accesses for seizures in the emergency department? An observational analysis of a paediatric cohort in the Southern ItalyCovid-19 Published on 2020-10-232022-10-30 Journal: Neurological Sciences [Category] Coronavirus, MERS, SARS, [키워드] activities Administered Admission Analysis caused changes children Cohort concerning COVID-19 DST eligible event febrile global pandemic incidence increase in Italian Italy latency lockdown media median age MMD Mobile media devices negative correlation overlapping Patient physical Prevalence Psychiatric disorders questionnaire reported Result screen time Seizure Seizures sleep disorder Spearman’s ρ statistically significant difference supplementary material Trigger TST two groups were excluded WHO World Health Organization [DOI] 10.1007/s10072-020-04824-5 PMC 바로가기 [Article Type] Covid-19
Twelve Children with Varicella Vaccine Meningitis: Neuropathogenesis of Reactivated Live Attenuated Varicella Vaccine Virus수두 백신 수막염이 있는 열두 명의 어린이: 재활성화된 생약화 수두 백신 바이러스의 신경병리학Review Published on 2020-09-252023-05-24 Journal: Viruses [Category] Fulltext, 대상포진, 두창, 수두, 홍역, [키워드] herpes vaccine herpes zoster latency RNA polymerase III trigeminal ganglion Varicella-Zoster Virus viral meningitis VZV gC [DOI] 10.3390/v12101078 PMC 바로가기 [Article Type] Review
The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic reviewReview Published on 2020-09-092022-10-04 Journal: Virus research [Category] SARS, 유전자 메커니즘, [키워드] accompanied addition C-lectin pathways candidate gene Case report caused CCR1 CCR9 coronavirus coronavirus endoribonuclease COVID-19 COVID-19 case COVID-19 GWAS COVID-19 pathogenesis Cytokine storm DC-SIGN DC-SIGN, Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin DC-SIGNDendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin deficiency Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin disease double-strand RNA dsRNA, double-strand RNA dsRNAdouble-strand RNA dysregulated endoU, coronavirus endoribonuclease endoUcoronavirus endoribonuclease Evidence explain expression genetic study Genetic variant genome wide association studies GWAS GWAS, genome wide association studies GWASgenome wide association studies Herpes Simplex Virus 1 herpses simplex encephalitis Host host genetics Host immune defenses HSE, herpses simplex encephalitis HSEherpses simplex encephalitis HSV-1, Herpes Simplex Virus 1 HSV-1Herpes Simplex Virus 1 Human hypothese IL-18 IL-18 binding protein IL-18BP, IL-18 binding protein IL-18BPIL-18 binding protein immune immune response gene immune system implicated inborn errors of immunity Inclusion Inflammasome inflammasome activation Interaction interferon Interleukins International Union of Immunological Societies IUIS, International Union of Immunological Societies IUISInternational Union of Immunological Societies lactate dehydrogenase latency LDH, lactate dehydrogenase LDHlactate dehydrogenase lectin manifestation medical subject heading MeSH, medical subject heading MeSHmedical subject heading Meta-analysis minor allele frequency NLRP1 objective OMIM, Online Mendelian Inheritance in Man (OMIM) OMIMOnline Mendelian Inheritance in Man (OMIM) Online Mendelian Inheritance in Man (OMIM) Pathogenesis pathway Pathways PBMCs, peripheral blood mononuclear cells PBMCsperipheral blood mononuclear cells Peripheral blood mononuclear cells Protein reported Result SARS Coronavirus SARS coronavirus 2 SARS-coronavirus 2 SARS-CoV SARS-CoV-2 SARS-CoV-2, SARS Coronavirus 2 SARS-CoV-2SARS Coronavirus 2 SARS-CoV, SARS Coronavirus SARS-CoVSARS Coronavirus severe COVID-19 Study design susceptibility systematic review therapeutic targets TLR pathway TLR pathways treatment for COVID-19 variant viral disease viral infection Viral susceptibility [DOI] 10.1016/j.virusres.2020.198163 PMC 바로가기 [Article Type] Review
Does Sars-Cov-2 threaten our dreams? Effect of quarantine on sleep quality and body mass indexResearch Published on 2020-08-182022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, MERS, [키워드] addition age baseline BMI BMI value BMI values body mass index changes Cohort COVID 19 COVID-19 dysfunction Effect Efficiency enrolled evaluated female females Gender increase in index latency male males material Nutritionist obesity objective outpatient clinic parameters physical activity Pittsburgh Quality quarantine questionnaire Result SARS-CoV-2 significant increase significantly Sleep Sleep disturbance sleep quality Smart-working statistical significance subject was related were assessed worsened worsening [DOI] 10.1186/s12967-020-02465-y PMC 바로가기 [Article Type] Research
Sleep Pattern Changes in Nursing Students during the COVID-19 LockdownArticle Published on 2020-07-202022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] 95% CI affected aggressive behavior alcohol Analysis change changed changes changes in components conducted coronavirus COVID-19 cut-off determine Dietary changes Efficiency FIVE latency lockdown nonparametric test Nursing pandemic Parametric pattern Pittsburgh Prevalence reduced Seven significantly Sleep sleep disorders sleep quality Standard deviation statistically stratified student were used women [DOI] 10.3390/ijerph17145222 PMC 바로가기 [Article Type] Article
Epigenetic Regulator miRNA Pattern Differences Among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 World-Wide Isolates Delineated the Mystery Behind the Epic Pathogenicity and Distinct Clinical Characteristics of Pandemic COVID-19SARS-CoV, SARS-CoV-2 및 SARS-CoV-2 전 세계 분리주 사이의 후성유전 조절자 miRNA 패턴 차이로 팬데믹 COVID-19의 서사적 병원성과 독특한 임상적 특징 뒤에 숨겨진 미스터리Genetics Published on 2020-07-102022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] alleviate anomalies Anomaly antiviral miRNAs autophagy binding breathing complications cardiovascular diseases cellular miRNA cellular pathway clinical Comorbidities Complication computational approach Computational approaches country COVID-19 COVID-19 patients death death rates diabetes difference disease effective epigenetic modulator epigenetic regulator experiments Factors functional Gene Expression Host host antiviral miRNA host genes host immunity host miRNA host's miRNAs human cell IFN-I IFN-I signaling immune regulation immune-escape mechanism immune-signaling pathways implication isolate latency lead Microarray miRNA miRNA clusters miRNA-mediated interaction miRNA-microRNA miRNAs mode modulate molecular mechanism Neutralizing normalized over representation analysis Pathogenesis Pathways patients with comorbidity pattern predict predicted profile regulator RNA therapeutics RNA-Seq SARS virus SARS viruses SARS-CoV SARS-CoV and SARS-CoV-2 viral miRNAs SARS-CoV and SARS-CoV-2 viruses SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 miRNAs SARS-CoV-2 pathogenesis SARS-CoV-2 viral SARS-CoV-2 virus SARS-infected human cell microarray signaling pathways Support symptoms of COVID-19 target targets the SARS-CoV-2 Viral viral miRNA viral miRNAs viral pathogenesis viruses [DOI] 10.3389/fgene.2020.00765 PMC 바로가기 [Article Type] Genetics
Is Guillain-Barrè syndrome triggered by SARS-CoV-2? Case report and literature reviewOriginal Article Published on 2020-07-092022-10-30 Journal: Neurological Sciences [Category] COVID-19, MERS, [키워드] acute respiratory syndrome AIDP cerebrospinal fluid clinical entities clinician coronavirus coronavirus disease correlation Course COVID-19 COVID-19 patient defined demyelinating described description Diagnosis distal etiological F wave gastrointestinal symptoms Guillain-Barrè latency less literature review lower limbs manifestation monophasic muscular neurological neurological manifestations Neuropathy Para-infectious Polyradiculoneuropathy positive reported respiratory responsible SARS-CoV-2 Support Swab Symptom syndrome tested the SARS-CoV-2 Trigger triggered virus weakness [DOI] 10.1007/s10072-020-04553-9 PMC 바로가기 [Article Type] Original Article
Bromodomain Inhibitors as Therapeutics for Herpesvirus-Related Disease: All BETs Are Off?article Published on 2020-07-022024-09-02 Journal: Frontiers in Cellular and Infection Microbiology [Category] 대상포진, [키워드] BET bromodomain inhibitor epigenetics herpesvirus latency Reactivation therapy [DOI] 10.3389/fcimb.2020.00329 PMC 바로가기 [Article Type] article
Clinical and Histopathological Features and Potential Pathological Mechanisms of Skin Lesions in COVID-19: Review of the LiteratureReview Published on 2020-06-302022-11-01 Journal: Dermatopathology [Category] COVID-19, [키워드] appear articles Case report children clinical clinical form clinical manifestations clinical presentation clinical symptom COVID-19 COVID-19 cases COVID-19 patient COVID-19 symptoms cutaneous manifestation database described epidermal feature Frequency histopathological feature Histopathology Infection Inflammatory latency lesion lesions literature majority male mechanisms microvascular injury Necrosis pathological Patient patients pediatric Potential presenting reported review SARS-CoV-2 severe cases severity skin skin lesion skin lesions syndrome the patient Vascular Vesicle with COVID-19 [DOI] 10.3390/dermatopathology7010002 PMC 바로가기 [Article Type] Review