Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescentsSARS-CoV-2 회복기의 장기 추적 및 예방 접종 중 스파이크 및 뉴클레오캡시드 특이적 면역의 역학Article Published on 2022-01-102022-09-10 Journal: Nature Communications [Category] 진단, 치료법, [키워드] Anti-viral immunity antibody antibody levels Antibody titers Asymptomatic BNT162b2 BNT162b2 mRNA boost circulating convalescent convalescent individual convalescent individuals correlated Decline declined delayed response Dynamics follow-up period Frequency Immunity increase in individual Infection long-lasting Long-term follow-up mild SARS-CoV-2 infection mRNA naïve vaccinees neutralizing antibody titers nucleocapsid Outcomes research responded to vaccination SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific T cells selective specific immunity spike strength T cell T cell response T cells vaccination viral infection virus-neutralizing antibody waning immunity [DOI] 10.1038/s41467-021-27649-y PMC 바로가기 [Article Type] Article
COVID-19 in Joint Ageing and Osteoarthritis: Current Status and Perspectives관절 노화 및 골관절염의 COVID-19: 현황 및 전망Review Published on 2022-01-102022-09-12 Journal: International Journal of Molecular Sciences [Category] 진단, [키워드] accelerated adipose Adipose tissue Ageing aging aging process analyzed angiotensin angiotensin-converting enzyme 2 calcium Characteristics Connective tissues contribute COVID-19 COVID-19 patients current deficiency dysfunction Effect endothelial evaluated explain exploration expression hypovitaminosis Hypovitaminosis D Inflammation joint joint and muscle pain knowledge long-COVID long-lasting molecular morbidity muscle pain Musculoskeletal musculoskeletal aging musculoskeletal symptom neuronal function new treatment strategy Osteoarthritis Pain Perturbation perturbations phenotype primary site recent Renin renin-angiotensin system road SARS-CoV-2 Society status Symptom tissue Topic Treatment [DOI] 10.3390/ijms23020720 PMC 바로가기 [Article Type] Review
Substantial Impact of COVID-19 on Self-Reported Mental Health of Healthcare Professionals in the NetherlandsPublic Health Published on 2022-01-102022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] affected Anxiety Burnout caused contrary COVID-19 COVID-19 infection COVID-19 pandemic decrease feeling healthcare Healthcare professional healthcare professionals hospital hospitals Impact increasingly Initially investigated long-lasting measure Mental mental health mental health problem Netherland pandemic Patient patients prevalent professional Psychological question SARS-CoV-2 social distancing Stress Support Symptom The Netherlands Treatment [DOI] 10.3389/fpubh.2021.796591 PMC 바로가기 [Article Type] Public Health
Immunity to SARS-CoV-2 up to 15 months after infectionArticle Published on 2022-01-072022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract antibodies B cells Beta concerning COVID-19 convalescent patients COVID-19 patient Delta Gamma IgG antibody immune response Immunity immunology implication Infection long-lasting majority memory B memory B cell natural infection Neutralizing activity neutralizing antibody Patient plasma plasma neutralizing titer Postinfection SARS-CoV-2 significant decrease Specific symptoms onset the SARS-CoV-2 Vaccines variant variants of concern Virology [DOI] 10.1016/j.isci.2022.103743 PMC 바로가기 [Article Type] Article
Diet and Hygiene in Modulating Autoimmunity During the Pandemic EraImmunology Published on 2022-01-052022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] approach autoimmune condition Autoimmunity contribute COVID-19 Defense diet Effect environmental factor homeostasis Host hygiene immune Immune homeostasis immune response immune system Immunological memory immunomodulation incidence individual Inflammatory response long-lasting measure micronutrients mitigate modulate pandemic populations promote SARS-CoV-2 severity of COVID-19 Still systemic lupus erythematosus Tolerance [DOI] 10.3389/fimmu.2021.749774 PMC 바로가기 [Article Type] Immunology
Sustained Delivery of SARS-CoV-2 RBD Subunit Vaccine Using a High Affinity Injectable Hydrogel Scaffold고친화성 주사 가능한 하이드로겔 지지체를 사용한 SARS-CoV-2 RBD 소단위 백신의 지속 전달Article Published on 2022-01-012022-09-12 Journal: Advanced Healthcare Materials [Category] MERS, SARS, 진단, [키워드] Activation acute respiratory syndrome Administered affinity antibody approach cellular cellular immunity circulating comparable coronavirus coronavirus disease COVID-19 delivery demonstrated Efficacy effort elicit ENhance Germinal center host cell humoral Humoral immunity hydrogel induce Inflammatory injectable hydrogel scaffolds Injections innate immune cell Local long-lasting lymphoid tissues mice Pathogens Prolonged provide RBD Reactions Receptor binding Receptor binding domain robust SARS-CoV-2 SARS-CoV-2 RBD serum IgG severe acute respiratory syndrome coronavirus 2 receptor binding domain Spike protein Subunit vaccine sustained sustained release T cell responses Vaccine development Vaccines viral entry [DOI] 10.1002/adhm.202101714 PMC 바로가기 [Article Type] Article
T cell phenotypes in COVID-19 – a living reviewShort Communication Published on 2021-12-292022-10-29 Journal: Oxford Open Immunology [Category] COVID-19, [키워드] Activation Adaptive immune response alteration antigen-specific characterisation characterized children clearance COVID-19 disease severity driver highlight immune immune function immune memory implication investigated knowledge likelihood long-lasting lung Lungs lymphopenia marker markers of activation mechanism Peripheral blood Phenotypes Post-infection predict PROTECT Re-infection SARS-CoV-2-specific T cell T cell T cell memory T cell phenotype T cell response T cell subset T cells tissue damage Vaccine development virus virus clearance [DOI] 10.1093/oxfimm/iqaa007 PMC 바로가기 [Article Type] Short Communication
Pros and Cons of CAD/CAM Technology for Infection Prevention in Dental Settings during COVID-19 OutbreakCOVID-19 발생 시 치과 환경에서 감염 예방을 위한 CAD/CAM 기술의 장단점Review Published on 2021-12-222022-09-10 Journal: Sensors (Basel, Switzerland) [Category] SARS, 치료기술, [키워드] Activation aerosol Asymptomatic case Asymptomatic cases COVID-19 COVID-19 pandemic dental dentistry digital technology dormant ECDC Effectiveness Evidence focus fomite guidelines identify immune protection Infection Infection prevention information International intraoral scanning limitation long-lasting manifestation microbial microbial infections National oral cavity oral manifestations Patient prevention Pro promotion reconditioning reported Safety Saliva SARS-CoV-2 SARS-CoV-2 transmission setting technology Triage vaccination ward Waves [DOI] 10.3390/s22010049 PMC 바로가기 [Article Type] Review
“World in motion” – emulsion adjuvants rising to meet the pandemic challengesReview Article Published on 2021-12-212022-10-04 Journal: NPJ Vaccines [Category] 비임상, [키워드] adaptive immune responses adjuvant adjuvants Administered antibody Antigen AS03 characterized clinical experience component cross-neutralizing defined dose draining lymph nodes Effectiveness Emulsion H1N1 influenza highlight human immunity immune response immune responses immunological responses induce Infectious diseases influenza vaccine injection long-lasting long-lived plasma cells mechanism mechanism of action memory B cells MF59 pandemic platform Population response rising safety profile SARS-CoV-2 pandemic Seasonal influenza T cell response Vaccine Vaccines variants Viral variants [DOI] 10.1038/s41541-021-00418-0 PMC 바로가기 [Article Type] Review Article
Temporal Patterns of COVID-19-Associated Pulmonary Pathology: An Autopsy StudyPathology Published on 2021-12-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress age alveolar alveolar cell Autopsy Bulgaria cause Cell change changes in clinical complication clinically Cohort coronavirus COVID-19 criteria develop disease disease onset distress Endotheliitis Endothelitis expired female fibrosis Gross Hematoxylin and eosin Histopathology hyaline membrane independent Infection interstitial light microscopy long-lasting lung changes Lungs male manifested Marina material mechanism morbidity and mortality notable Novel coronavirus novel coronavirus disease pathology Patient pattern polymerase chain Probability pulmonary pulmonary morphology Pulmonary pathology respiratory tract Result SARS-CoV-2 selected severe complication severe COVID-19 severe disease severity significantly increased squamous cell metaplasia symptom onset syndrome Temporal the disease the mean Type II pneumocyte university variant Varna Vascular withdrawn [DOI] 10.7759/cureus.20522 PMC 바로가기 [Article Type] Pathology