moderate disease – Page 9 – Communicable Diseases Research

Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers

COVID-19 환자의 대사체 분석은 단계 의존적 및 예후 바이오마커를 밝힙니다.

Clinical Trial

Published on 2021-03-112022-08-13
Journal: Cell Death & Disease [Category] SARS, 바이오마커, 임상, 진단,

Low Sensitivity of Admission Lung US Compared to Chest CT for Diagnosis of Lung Involvement in a Cohort of 82 Patients with COVID-19 Pneumonia

COVID-19 폐렴 환자 82명 코호트에서 폐 침범 진단을 위한 흉부 CT와 비교한 입원 폐 US의 낮은 민감도

Article

Published on 2021-03-042022-09-10
Journal: Medicina [Category] SARS, 진단, 치료기술,

[키워드] (Computed Tomography Abnormalities abnormality Admission calculated Chest-CT clinical evaluation Computed tomography consolidation coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia crazy-paving pattern CT finding CT findings Department detect diagnostic test diagnostic tests disease Emergency emergency department Ground-glass opacities ground-glass opacity hospital integration interstitial pneumonia Involvement lung lung involvement lung ultrasound (LUS) Mild Mild disease moderate disease Nasopharyngeal swab objective Patient performed Pneumonia presenting pulmonary lesion pulmonary lesions ranged recruited reference standard Result SARS-CoV-2 SARS-CoV-2 pneumonia sensitivity severe disease subpleural with COVID-19 zone
[DOI] 10.3390/medicina57030236 PMC 바로가기 [Article Type] Article

Loss of smell and taste in COVID-19 infection in adolescents

청소년의 COVID-19 감염에서 후각과 미각 상실

Article

Published on 2021-03-012022-09-11
Journal: International journal of pediatric otorhinolaryngo [Category] SARS, 치료기술,

Serum β 2 -microglobulin levels in Coronavirus disease 2019 (Covid-19): Another prognosticator of disease severity?

코로나바이러스 질병 2019(Covid-19)의 혈청 β 2 -마이크로글로불린 수준: 질병 중증도의 또 다른 예후 인자?

Observational Study

Published on 2021-03-012022-09-10
Journal: PLoS ONE [Category] 바이오마커, 임상,

[키워드] accompanied Admission age ANOVA test Arabian Peninsula Care circulation Cohort confirmation conformation Control controls coronavirus disease Coronavirus disease 2019 disease disease severity disorder domain elevated Ethnicity etiology FIVE hospital Increases increases in infected with SARS-CoV-2 kDa limitation linear MHC MHC class MHC class I microglobulin Mild Mild disease moderate disease on admission outcome Pathogenesis Patient predict Protein protein complex Sample size Saudi Arabia severe COVID-19 severe disease severity Severity of disease Shed single-center study the major histocompatibility uninfected Viral viral infections were measured WHO
[DOI] 10.1371/journal.pone.0247758 PMC 바로가기 [Article Type] Observational Study

The characteristics of HIV-positive patients with mild/asymptomatic and moderate/severe course of COVID-19 disease-A report from Central and Eastern Europe

COVID-19 질병의 경증/무증상 및 중등도/중증 경과를 가진 HIV 양성 환자의 특성-중부 및 동부 유럽의 보고서

Article

Published on 2021-03-012022-09-11
Journal: International Journal of Infectious Diseases [Category] SARS, 치료제,

[키워드] Albania Analysis antiretroviral Antiretroviral therapy Asymptomatic Bulgaria Characteristics characteristics of patient collected comparable contrary contribute country Course COVID-19 COVID-19 disease Czech Republic diagnosed with COVID-19 Estonia Europe Evidence except for Factor FIVE General population group HIV Hospitalization Hungary immunological inhibitor Lithuania Mild disease moderate disease network non-nucleoside reverse transcriptase inhibitors nucleoside Patient patients performed Poland Prospective Study protease inhibitors regimen reported respiratory Respiratory failure Retrospective analysis reverse transcriptase Romania Russia SARS-CoV-2 SARS-COV-2 infection severe disease severity statistical analysis systemic symptom transcriptase Treatment Viral with mild disease
[DOI] 10.1016/j.ijid.2020.12.026 PMC 바로가기 [Article Type] Article

Clonal expansion and activation of tissue-resident memory-like T H 17 cells expressing GM-CSF in the lungs of patients with severe COVID-19

중증 COVID-19 환자의 폐에서 GM-CSF를 발현하는 조직 상주 기억 유사 T H 17 세포의 클론 확장 및 활성화

Research Article

Published on 2021-02-232022-09-12
Journal: Science Immunology [Category] Fulltext, MERS, 진단,

[키워드] Activation acute respiratory distress acute respiratory distress syndrome Analysis Autoimmune diseases Bacterial bacterial pneumonia BAL Blood Bronchoalveolar lavage Bronchoalveolar lavage fluid CD8 Cell cell type cells cellular characterized Clinical course clonal expansion clone Cohort cohort of patient collected contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia CSF2 cytokine cytokine expression profile disease severity elevated expressing feature Generation GM-CSF helper high mortality hyperinflammation identify IL-17A IL17A Immune cell immune cell type immune cells immune response Immunopathogenesis interactome investigated involved lung lung damage Lung injury Lung pathology lung tissue Lungs Macrophage macrophages mechanism memory T cell moderate disease pathogenic Patient patients with COVID-19 Pneumonia protein level pulmonary T respiratory distress Respiratory distress syndrome serum severe coronavirus disease severe COVID-19 Severe COVID-19 pneumonia single-cell subsequent syndrome T cell T cell response T cells T helper TCR Th17 cells Therapies tissues Transcriptome Viral viral clearance viral infection
[DOI] 10.1126/sciimmunol.abf6692 PMC 바로가기 [Article Type] Research Article

Thirty-day readmission rate of COVID-19 patients discharged from a tertiary care university hospital in Turkey: an observational, single-center study

터키의 3차 치료 대학 병원에서 퇴원한 COVID-19 환자의 30일 재입원률: 관찰, 단일 센터 연구

Observational Study

Published on 2021-02-202022-09-11
Journal: International journal for quality in health care : [Category] 임상, 치료기술,

[키워드] 2019 30-day readmission rate Adult patient Adult patients age Cancer cancers Care cause causes Clinical data coronavirus coronavirus disease COVID-19 COVID-19 patient database detect Diagnosis diagnosis of COVID-19 died discharge discharged disease Factor health information Health information system hospital Hospitalized hypertension information information management Information System interquartile range malignancy management median time metastatic cancers Mild Mild disease moderate Moderate COVID-19 moderate disease Patient patient information patient safety predictor readmission readmission. Research retrieved Sepsis severity single-center study System the patient Two patient two patients university hospital was recorded
[DOI] 10.1093/intqhc/mzaa144 PMC 바로가기 [Article Type] Observational Study

A quadruple blinded placebo controlled randomised trial to evaluate the effectiveness of an Iodine complex for patients with mild to moderate COVID-19 in Pakistan (I-COVID-PK): A structured summary of a study protocol for a randomised controlled trial

파키스탄에서 경증에서 중등도의 COVID-19 환자에 대한 요오드 복합체의 효과를 평가하기 위한 4중 맹검 위약 대조 무작위 시험(I-COVID-PK): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-02-102022-09-10
Journal: Trials [Category] MERS, 임상,

[키워드] 30-Day mortality Admission age alleviation alleviation of symptom approved Arm ARMS baseline blinded Blinding calculated Care care providers Chest chest scan Chronic illness clinic clinical Clinical improvement Clinical management co-morbidities co-morbidity comparator complex coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 adult patient COVID-19 adult patients Disinfection dissemination doctor Effectiveness Efficacy element enrolled evaluate excluded four group four groups Gender groups HRCT Infection information initial initial symptom initial symptoms Intention investigator investigators Iodine IRB lung involvement management guidelines Mild mild to moderate mild to moderate disease Moderate COVID-19 moderate disease morbidities National Health Service National Health Services non-pregnant females number objective outcome Pakistan participant Participants Patient patients PCR Placebo placebo-controlled Polymer positive Primary outcomes protocol radiological radiological improvement randomised randomised controlled trial Randomised trial randomization Randomized receiving recruited recruitment Registered remained reported resolved RT-PCR Sample size SARS-CoV-2 RT-PCR secondary outcome severity severity of symptom shown Standard standard care status Study protocol supplementary material Symptom symptomatic syrup the patient time Trial Version Viral viral clearance website
[DOI] 10.1186/s13063-021-05081-3 PMC 바로가기 [Article Type] Letter

Hematological and biochemical abnormalities associated with severe forms of COVID-19: A retrospective single-center study from Morocco

심각한 형태의 COVID-19와 관련된 혈액학적 및 생화학적 이상: 모로코의 후향적 단일 센터 연구

Observational Study

Published on 2021-02-042022-09-10
Journal: PLoS ONE [Category] MERS, 임상, 치료기술,

[키워드] Abnormalities abnormality Admission advanced age affected African age Alanine alanine aminotransferase Analysis analyzed aspartate Aspartate aminotransferase biochemical biological parameter biological parameters Blood cells C-reactive protein Characteristics clinical clinician Cohort Comorbidities conducted coronavirus coronavirus disease COVID-19 creatinine Critical disease CRP D-dimers deaths detect died disease Disease progression early stage environmental factor Epigenetic Evolution Factor ferritin form Genetic Genetic studies group Health Health crisis Health Sciences Hospitalization Hospitalized identify immunological individual Infection Lactate lactate dehydrogenase LDH literature review Lymphocytes male Male sex median age Mild mild to moderate mild to moderate disease moderate moderate disease MONITOR Morocco Neutrophils non-severe patients North pandemic parameter Patient patients older Predictive presence of comorbidities procalcitonin progression radiological retrospective Retrospective study risk factor Risk factors severe and non-severe patients severe disease severity single-center single-center study survived the median Univariate analysis university was performed WBC White blood cell White blood cells
[DOI] 10.1371/journal.pone.0246295 PMC 바로가기 [Article Type] Observational Study

The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity

Clinical Trial

Published on 2021-02-012022-10-05
Journal: The Journal of Clinical Investigation [Category] 임상,