mouse – Page 9 – Communicable Diseases Research

Inhaled [D-Ala 2 ]-Dynorphin 1-6 Prevents Hyperacetylation and Release of High Mobility Group Box 1 in a Mouse Model of Acute Lung Injury

Research Article

Published on 2021-09-272022-10-29
Journal: Journal of Immunology Research [Category] COVID-19,

[키워드] abrogate acute lung injury acute respiratory distress airway epithelial cell ARDS bind Box caused cellular chemokines COVID-19 Critical Cytokine storm Cytokines cytoplasm disease severity Effect endothelial cells enzyme expression Extracellular group HMGB1 HMGB1 release HMGB1 secretion identify immune cells Inflammatory Inflammatory mediators Inhaled inhibit life-threatening lung Lung diseases lysine mechanism of action mice Mobility Model modulation mouse nuclear nucleus occur peptide Pneumonia posttranslational modifications Proinflammatory cytokine Protein pulmonary inflammation RAGE receptors redox state Release released residue respiratory infection significantly SIRT1 syndrome the SARS-CoV-2 virus therapeutic TLR4 toll-like receptor 4 translocation treating COVID-19 Treatment
[DOI] 10.1155/2021/4414544 PMC 바로가기 [Article Type] Research Article

Effects of endurance training on the expression of host proteins involved in SARS‐CoV‐2 cell entry in C57BL/6J mouse

Original Article

Published on 2021-09-142022-10-28
Journal: Physiological Reports [Category] COVID-19, SARS,

Development of an mRNA-LNP Vaccine against SARS-CoV-2: Evaluation of Immune Response in Mouse and Rhesus Macaque

Article

Published on 2021-09-102022-10-28
Journal: Vaccines [Category] COVID-19,

PTX Instructs the Development of Lung-Resident Memory T Cells in Bordetella pertussis Infected Mice

PTX는 백일해균 감염 마우스에서 폐 거주 기억 T 세포의 발달을 지시합니다.

Article

Published on 2021-09-082024-07-28
Journal: Toxins [Category] 백일해,

[키워드] Bordetella pertussis lung mouse Pertussis toxin resident memory T cells
[DOI] 10.3390/toxins13090632 PMC 바로가기 [Article Type] Article

Targeting of Protein’s Messenger RNA for Viral Replication, Assembly and Release in SARS-CoV-2 Using Whole Genomic Data From South Africa: Therapeutic Potentials of Cannabis Sativa L

Pharmacology

Published on 2021-09-022022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] activity Analysis assembly attack bat binding affinity cannabinol cannabis Cannabis sativa China Clinical studies coding computational tools country COVID-19 docking envelope Genome glycoprotein homology IBV implicated in viral Interaction investigated Italy MERS-CoV messenger MHV Middle East mouse mRNA mRNAs Nucleocapsid phosphoprotein ORF1ab other coronaviruses Patient phytocannabinoids Potential potential therapy Protein Release Replication respiratory RNA SARS CoV SARS-CoV-2 South South Africa Spain Spectroscopy Spread surface targeting translation United States viral nucleotide whole genome
[DOI] 10.3389/fphar.2021.736511 PMC 바로가기 [Article Type] Pharmacology

Animal Models for COVID-19: Hamsters, Mouse, Ferret, Mink, Tree Shrew, and Non-human Primates

Microbiology

Published on 2021-08-312022-10-31
Journal: Frontiers in Microbiology [Category] COVID-19,

Multi-Organ Histopathological Changes in a Mouse Hepatitis Virus Model of COVID-19

Article

Published on 2021-08-272022-10-28
Journal: Viruses [Category] COVID-19, MERS, SARS,

[키워드] alveolar animal model Asymptomatic Blood blood vessels Brain bronchiolar capillary cause Cell change changes characterized cortical COVID-19 COVID-19 pandemic Cytokine storm death distal edema epithelial hemorrhage Hemorrhagic Hepatitis Human humans hyaline membrane formation infect Infection infiltration inoculated interstitial interstitial tissue intra-alveolar liver macrophages mechanism mice Mild Model moderate mononuclear cell mouse mouse hepatitis virus-1 multiorgan histopathology Necrosis necrotic necrotic debris Neuron nuclei organ system oxidative stress pathophysiologic peribronchiolar perivascular Pneumonia precipitated red blood cells renal reported representing Respiratory illness responsible Safe SARS-CoV-2 SARS-CoV-2 infected individual SARS-COV-2 infection Septic shock severe lung inflammation severe symptom therapeutic interventions thrombosis thrombotic event Tubular Necrosis uninfected vascular congestion vascular defect vessels virus was used weight loss widespread
[DOI] 10.3390/v13091703 PMC 바로가기 [Article Type] Article

An easy method for developing fusion enabled SARS-CoV2 virus fusion mimic (SCFM), bypassing the need of Bio Safety Level (BSL) facility

Research Article

Published on 2021-08-262022-10-27
Journal: Bioengineered [Category] COVID-19,

An easy method for developing fusion enabled SARS-CoV2 virus fusion mimic (SCFM), bypassing the need of Bio Safety Level (BSL) facility

Research Article

Published on 2021-08-262022-10-27
Journal: Bioengineered [Category] Coronavirus, COVID-19, Fulltext, SARS,

Mild and Severe SARS-CoV-2 Infection Induces Respiratory and Intestinal Microbiome Changes in the K18-hACE2 Transgenic Mouse Model

경증 및 중증 SARS-CoV-2 감염은 K18-hACE2 형질전환 마우스 모델에서 호흡기 및 장내 미생물군유전체 변화를 유도합니다

Research Article

Published on 2021-08-112022-09-10
Journal: Microbiology Spectrum [Category] MERS, SARS, 치료제,

[키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Affect Antiviral Antiviral treatment Bacteroidete Bacteroidetes cecum change changes in characterized Clinical sign Clinical signs coronavirus COVID-19 COVID-19 pandemic death deaths declining Decreased develop disease dissimilarity dosage dose dose-dependent manner family Firmicute firmicutes groups hACE2 High dose High-dose immune system increasingly independent independent of Infection inhibitor intestinal intestine K18-hACE2 K18-hACE2 mice K18-hACE2 transgenic mice less lung Lungs M pro mice microbe microbes microbial Microbiome Model mouse presence or absence prevalent Proteobacteria respiratory respiratory infection respiratory infections SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe SARS severe SARS-CoV-2 significantly Treatment Verrucomicrobia Viral viral infections virus with infection
[DOI] 10.1128/Spectrum.00536-21 PMC 바로가기 [Article Type] Research Article