CytoSorb Rescue for COVID-19 Patients With Vasoplegic Shock and Multiple Organ Failure: A Prospective, Open-Label, Randomized Controlled Pilot StudyRandomized Controlled Trial Published on 2022-06-012022-10-04 Journal: Critical Care Medicine [Category] 임상, [키워드] 1:1 95% CI adjusted Adsorption adverse event age Antibiotics Berlin C-reactive protein clinical concentrations control group Controlled COVID-19 COVID-19 patient COVID-19 patients cytokine dose Effect Endpoint enrolled excluded Gender greater groups hazard ratio Hemodialysis ICU IMPROVE inflammatory markers interleukin-6 interquartile range IQR junction measurement median membrane Monmouth Mortality mortality rate Multiple one patient Patient pilot study primary endpoint Prospective Randomized receive reduction Registered registry rescue Resolution secondary Secondary endpoints Shock Standard of care Standard therapy study inclusion the primary endpoint treatment group university hospital variable Withdrawal [DOI] 10.1097/CCM.0000000000005493 PMC 바로가기 [Article Type] Randomized Controlled Trial
Humoral and Cellular Responses to BNT162b2 as a Booster Following Two Doses of ChAdOx1 nCov-19 Determined Using Three SARS-CoV-2 Antibody Assays and an Interferon-Gamma Release Assay: A Prospective Longitudinal Study in Healthcare Workers세 가지 SARS-CoV-2 항체 분석 및 인터페론-감마 방출 분석을 사용하여 결정된 2회 용량의 ChAdOx1 nCov-19 후 부스터로서의 BNT162b2에 대한 체액 및 세포 반응: 의료 종사자에 대한 전향적 종단 연구Article Published on 2022-06-012022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Abbott Adverse reactions antibody antibody assay Antibody titer assay BNT162b2 booster booster dose booster vaccination Booster vaccine cellular response Cellular responses ChAdOx1 ChAdOx1 nCoV-19 collected contribute coronavirus disease determine dose Genscript healthcare humoral IgG INF-γ information interferon-γ Laboratory longitudinal longitudinal change median Mild MOST Neutralizing antibodies neutralizing antibody participant Participants positive Prospective provide Quantitative questionnaire Release reported response Roche SARS-CoV-2 second dose significantly increased Spread vaccination Vaccine worker [DOI] 10.3389/fimmu.2022.859019 PMC 바로가기 [Article Type] Article
Factors Associated with Post-Acute Sequelae of SARS-CoV-2 (PASC) After Diagnosis of Symptomatic COVID-19 in the Inpatient and Outpatient Setting in a Diverse CohortObservational Study Published on 2022-06-012022-10-04 Journal: Journal of General Internal Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI acute COVID-19 Anosmia association baseline BMI Clinical characteristics clinical factor clinical symptom Cohort conducted COVID-19 COVID-19 infection death demographic development diabete evaluate Factor fatigue Follow-up functional greater hospital discharge Hospitalized hospitalized patient incidence index Infection information Inpatient laboratory-confirmed Medicaid Odds ratio Older age older patients Organ transplant Outpatient outpatients PASC Patient Population Prospective questionnaire risk factor risk of death SARS-CoV-2 setting Shortness of breath subset survivor Symptom symptomatic USA vulnerability while with COVID-19 [DOI] 10.1007/s11606-022-07523-3 PMC 바로가기 [Article Type] Observational Study
Lifestyle risk behaviours among adolescents: a two-year longitudinal study of the impact of the COVID-19 pandemicClinical Trial Published on 2022-06-012022-10-04 Journal: BMJ Open [Category] 임상, [키워드] age alcohol approach baseline changes in chronic disease clinical cohort study control group Course COVID-19 COVID-19 pandemic declined Epidemiology Gender group Health impacted IMPROVE lockdown maintain New pandemic Physical inactivity Prevalence prevalent Prospective public health reduced registry risk risk factor screen time South Support supported [DOI] 10.1136/bmjopen-2021-060309 PMC 바로가기 [Article Type] Clinical Trial
The Value of Lung Ultrasound to Detect the Early Pleural and Pulmonary Pathologies in Nonhospitalized COVID-19-Suspected Cases in a Population With a Low Prevalence of COVID-19 Infection: A Prospective Study in 297 SubjectsCOVID-19 감염 유병률이 낮은 집단에서 입원하지 않은 COVID-19 의심 사례에서 조기 흉막 및 폐 병리를 감지하기 위한 폐 초음파의 가치: 297명의 대상자를 대상으로 한 전향적 연구Article Published on 2022-06-012022-09-11 Journal: Journal of Ultrasound in Medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 air bronchogram bronchogram can not Chain Reaction consolidation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 infection COVID-19-suspected cases defined Diagnosis diagnostic Diagnostic accuracy disease early diagnosis evaluate examined Infection low prevalence lung Lung ultrasound Nasopharyngeal swab Negative predictive value nonhospitalized Pathologies pleura pleural and pulmonary pathologies. pleural effusion polymerase chain polymerase chain reaction Population positive Positive predictive value Predictive value Prevalence prevalence of COVID-19 Prospective Prospective Study pulmonary reverse transcription reverse transcription polymerase chain reaction RT-PCR RT-PCR test SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus specificity study participant Study participants subject subjects the disease the patient Ultrasound value visceral visceral pleura [DOI] 10.1002/jum.15822 PMC 바로가기 [Article Type] Article
Efficacy and Safety of ELOM-080 as Add-On Therapy in COVID-19 Patients with Acute Respiratory Insufficiency: Exploratory Data from the Prospective Placebo-Controlled COVARI TrialRandomized Controlled Trial Published on 2022-06-012022-10-05 Journal: Advances in therapy [Category] COVID19(2023년), SARS, 임상, [키워드] breath clearance clinical status COVID-19 double-blind Dyspnoea ELOM-080 enhancement enhancer enrolment EudraCT evaluated exploratory exploratory study had no hospitalisation hospitalised IMPROVE Inflammatory less MCC MCC enhancement Mucociliary clearance Patient patients treated patients with COVID-19 per-protocol Placebo PPS Prospective randomised recruitment required respiratory respiratory diseases Safety Shortness of breath. significant effect supplemental oxygen the placebo group therapy treat treating COVID-19 Trial [DOI] 10.1007/s12325-022-02135-z PMC 바로가기 [Article Type] Randomized Controlled Trial
Quality of life and persistent symptoms after hospitalization for COVID-19. A prospective observational study comparing ICU with non-ICU patientsObservational Study Published on 2022-06-012022-10-04 Journal: Revista española de anestesiología y reanimació [Category] COVID19(2023년), SARS, 임상, [키워드] Acute respiratorydistress (ARDS) Calidad de vidarelacionada con lasalud cohort study COVID-19 COVID-19 patient critically ill patients decrease defined described develop Dificultad respiratoriaaguda (SDRA) discharged Dyspnea English Estado funcional Functional status Health Health-relatedquality of life hospital Hospital admission Hospitalization ICU ICU admission ICU patient ICU Patients no difference non-ICU patient Pacientes críticos pacientes hospitalizado Patient patients died patients hospitalized Primary outcome proportion Prospective prospective observational study prospectivo Quality Quality of life questionnaire reduced reported required SARS-CoV-2 Spanish Symptom Symptoms worsening [DOI] 10.1016/j.redare.2022.06.002 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France반려동물의 SARS-CoV-2 감염: 프랑스의 전향적 혈청학적 조사 및 위험 인자 분석Article Published on 2022-05-282022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% confidence interval absence acute respiratory syndrome acute respiratory syndrome coronavirus animals appear canine cat cats chi-square test circulation clinics close contact contact with Coronavirus-2 COVID-19 dog Epidemiology episode episode of Factor France French household Hypothesis investigated neutralizing SARS-CoV-2 antibodies Occurrence Odds ratio P -value populations Prospective Prospective Study Region responsible risk Risk factors SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody serology seropositive Seropositivity Seroprevalence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 statistically significant survey Viral reservoir would increase [DOI] 10.3390/v14061178 PMC 바로가기 [Article Type] Article
SARS-CoV-2 RBD-specific and NP-specific antibody response of healthcare workers in the westernmost Austrian state Vorarlberg: a prospective cohort studySARS-CoV-2 RBD 특이적 및 NP 특이적 항체 반응은 오스트리아 최서단 Vorarlberg 주에서 의료 종사자들의 전향적 코호트 연구입니다.Article Published on 2022-05-242022-09-11 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody antibodies antibody Antibody Response Antigen antigens Clinical characteristics clinical chemistry cohort study comparable COVID-19 COVID-19 infection COVID-19 pandemic demographic and clinical characteristics different time point domain enrolled Epidemiology Factors First wave FIVE General population HCW HCWs healthcare worker Healthcare workers IgG antibodies incidence rate increased risk industrial medicine Infection infection control infections nucleocapsid protein occupational occupational & Prevalence Prospective prospective cohort study public health RBD Receptor-binding domain response reverse transcription PCR risk RT-PCR SARS-CoV-2 second wave Serological testing seropositive Seropositivity Seroprevalence specimen state hospital Surveillance Symptom the disease Vaccinations with COVID-19 working environment [DOI] 10.1136/bmjopen-2021-052130 PMC 바로가기 [Article Type] Article
Well-being app to support young people during the COVID-19 pandemic: randomised controlled trialRandomized Controlled Trial Published on 2022-05-192022-10-05 Journal: BMJ Open [Category] 임상, [키워드] Adolescent analysed Anxiety application baseline Care changes in clinical clinically Compassion controls coping skills COVID-19 COVID-19 pandemic Depression Developed effective Efficacy emotional Endpoint engage evaluate evaluated form group Health help index indicated individual Interaction intervention group linear mixed model media Mental mental health mHealth Mobile mobile apps New outcome outcomes pandemic participant Perceived Stress Scale physical Prospective Psychological Quality randomised controlled trial recruited registry remained Resilience scale secondary self self-compassion Seven significantly higher significantly lower Sleep statistically significant statistically significant difference Stress Support the WHO Usability Well-being young adult [DOI] 10.1136/bmjopen-2021-058144 PMC 바로가기 [Article Type] Randomized Controlled Trial