Severe COVID-19 in inflammatory bowel disease patients in a population-based settingResearch Article Published on 2021-10-052022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI Admission affected age BMI Clinical course comparable confidence Course COVID-19 COVID-19 patient Crohn’s disease death determine Follow-up General population hospital Hospitalization Hospitalized hospitalized patient IBD ICU admission impacted incidence rate increased risk Infection Inflammatory bowel disease IQR mechanical ventilation Netherlands objective Patient populations reflect Research Result severe COVID-19 statistically significant systemic medication ulcerative colitis [DOI] 10.1371/journal.pone.0258271 PMC 바로가기 [Article Type] Research Article
Consequences of the COVID-19 Lockdown in Germany: Effects of Changes in Daily Life on Musical Engagement and Functions of MusicArticle Published on 2021-10-052022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] affected asked attribute change connection consequence coronavirus COVID-19 COVID-19 pandemic Daily Effect Engagement Factor function Germany handling investigated killing killing time life lockdown logistic regression model loneliness music music listening pandemic participant reactivity reduced reflect Social distance spring Stress synchronization worries [DOI] 10.3390/ijerph181910463 PMC 바로가기 [Article Type] Article
Hospital presentations for self-poisoning during COVID-19 in Sri Lanka: an interrupted time-series analysisArticles Published on 2021-10-012022-10-30 Journal: The lancet. Psychiatry [Category] COVID-19, MERS, SARS, [키워드] 95% CI Abstract Admission age Analysis calculate Care clinician collected country COVID-19 determine Elizabeth Blackwell Evidence female females finding funding help hospital Hospital admission incidence individual Interaction lockdowns main analysis males material mental health pandemic Patient pesticide prevention public health public health measures reduction in reflect seeking Sex Suicide Teaching toxicology translation Treatment unit University of Bristol Wellcome Trust were excluded widespread with COVID-19 [DOI] 10.1016/S2215-0366(21)00242-X PMC 바로가기 [Article Type] Articles
Standardizing PaO2 for PaCO2 in P/F ratio predicts in-hospital mortality in acute respiratory failure due to Covid-19: A pilot prospective studyObservational Study Published on 2021-10-012022-10-05 Journal: European journal of internal medicine [Category] SARS, 임상, [키워드] Acute respiratory failure adjusted Analysis ARF AUROC Blood calculated COVID-19 death defined disease effort enrolled FiO2 fraction Hypocapnia hypoxemic in-hospital mortality Invasive mechanical ventilation maintain marker Mortality observé outcome oxygen Oxygenation P/F P/F ratio PaCO2 pandemic coronavirus PaO2 paO2/fiO2 pathophysiology Patient predict Prognosis Prospective Study Ratio receiver reflect Respiratory failure ROC ROC Curve severity Standard Standard PaO2. subject tachypnea [DOI] 10.1016/j.ejim.2021.06.002 PMC 바로가기 [Article Type] Observational Study
Quantifying bacterial evolution in the wild: A birthday problem for Campylobacter lineages야생에서 박테리아 진화를 정량화 : 캄 필로 박터 계통의 생일 문제Research Article Published on 2021-09-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accumulate Accuracy addition alteration Analysis approach approaches Bacteria Bacterial bacterium birthday problem Campylobacter Campylobacter jejuni clinical isolates CLOCK clock rate dataset DNA replication ecological effective estimates estimation event Evolution focus gastroenteritis gene transfer Genome genomic growth help horizontal gene Horizontal gene transfer Host humans identifying infect information introduced isolates lead Lineage lineages maintenance molecular molecular evolution Non-synonymous not applicable nucleotide nucleotide change nucleotide changes nucleotide sequence organism outbreak pathogen pathogenic bacteria pathogenic strains Pathogens Population Probability provide reducing reflect Region reproduction robust sampling selected Spread strain Strains synonymous toolkit transfer Transmission turnover Variation [DOI] 10.1371/journal.pgen.1009829 PMC 바로가기 [Article Type] Research Article
Estimating epidemiologic dynamics from cross-sectional viral load distributions단면 바이러스 부하 분포에서 역학적 역학 추정Article Published on 2021-09-262022-09-12 Journal: Science (New York, N.y.) [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect approach arising biases calibrated can be used Care Chain Reaction changes in collected conducted coronavirus Course cross cross-sectional Ct values current cycle threshold death declining develop Diseases distribution emerging viruses Epidemic estimate feature flexible framework growth growth rate highlight Hospital admission hospitalizations implication IMPROVE incidence individual individuals infected individual Infection infection prevalence Infectious diseases information inherent Intervention Long-term care management Massachusett Massachusetts mathematical mathematical model Metrics offer Older outbreak overcome pandemic performed polymerase chain polymerase chain reaction population distribution populations positive Precision proportion proportions provide Public health response Public health responses Quantitative random Random sample rationale real time reflect reflected repeated reported Reporting reproductive reveal reverse transcription reverse transcription quantitative polymerase chain reaction rising robust robustness RT-qPCR sample collection SARS-CoV-2 SARS-CoV-2 testing severe acute respiratory syndrome Coronavirus specimen Surveillance surveillance data surveillance testing the epidemic the median trajectory turn understanding variant variants Variation variety viral kinetics Viral load viral loads virus [DOI] 10.1126/science.abh0635 PMC 바로가기 [Article Type] Article
Does reactogenicity after a second injection of the BNT162b2 vaccine predict spike IgG antibody levels in healthy Japanese subjects?Research Article Published on 2021-09-202022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] 95% confidence interval adjusted adverse event Adverse reaction age antibody antibody production antibody unit blood sample BNT162b2 BNT162b2 vaccine calculated correlated geometric healthcare worker healthy IgG level injection Japanese log-transformed magnitude median Messenger RNA positively correlated predict Questionnaires reactogenicity reflect Sample size SARS CoV-2 severity Sex significantly spike spike IgG Vaccine virus spike protein [DOI] 10.1371/journal.pone.0257668 PMC 바로가기 [Article Type] Research Article
Development of a physiological model of human middle ear epitheliumOriginal Research Published on 2021-09-182022-10-30 Journal: The Laryngoscope [Category] COVID-19, [키워드] acute infection Antimicrobial therapy Biological models cells changed children ciliated clinical implication complex conditions Culture develop development disease Diseases epithelial epithelial cell epithelial cell type goblet immunofluorescence immunohistochemistry in vivo lack Level media membrane Microscopy mucosal otitis otitis media otorhinolaryngologic diseases physiological polymerase chain positive reflect Research respiratory mucosa Result Safe SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 shown subtype susceptible the healthy translational transmission electron microscopy Treatment undergo Ventilated [DOI] 10.1002/lio2.661 PMC 바로가기 [Article Type] Original Research
Skin manifestations associated with systemic diseases – Part I ☆ ☆☆Continuing Medical Education Published on 2021-09-172022-10-28 Journal: Anais Brasileiros de Dermatologia [Category] Coronavirus, MERS, SARS, [키워드] alteration biopsies cause Combination condition cutaneous manifestation Dermatology dermatomyositis described Diagnosis diagnostic disease Diseases eye functions group hematological Histopathology hypothese Infection Intention manifestation occur organ Part patients Protective provide pruritus Pyoderma gangrenosum raise recognize reflect renal sarcoidosis SARS-CoV-2 coronavirus skin manifestation Sweet syndrome systemic disease systemic diseases systemic lupus erythematosus Systemic scleroderma the disease variety Vascular Vasculitis [DOI] 10.1016/j.abd.2021.02.008 PMC 바로가기 [Article Type] Continuing Medical Education
Early Detection of Symptom Exacerbation in Patients With SARS-CoV-2 Infection Using the Fitbit Charge 3 (DEXTERITY): Pilot EvaluationOriginal Paper Published on 2021-09-162022-10-30 Journal: JMIR Formative Research [Category] COVID-19, [키워드] age Apple Watch asked Asymptomatic causes charge clinical COVID-19 COVID-19 symptom COVID-19 symptoms death defined detection Deterioration diagnosed discharged patient early stage enrolled estimated oxygen variation Exacerbation exhibiting extracorporeal membrane oxygenation female Fitbit help identify Infection Infectious disease mechanical ventilation MONITOR network objective obstructive sleep apnea occurred outcome Outpatient oxygen oxygen saturation Oxygenation Patient patients patients with COVID-19 per day physical activity physiological pilot study polymerase chain positive predict Primary outcome readmission recruited reflect Registration registry Result SARS-CoV-2 Secondary outcomes Sensitivity and specificity severity silent hypoxia Sleep sleep quality study period Symptom Symptoms syndrome unique university Variation wearable wearable device with COVID-19 [DOI] 10.2196/30819 PMC 바로가기 [Article Type] Original Paper