Respiratory illness – Page 9 – Communicable Diseases Research

What GI Physicians Need to Know During COVID-19 Pandemic

COVID-19 팬데믹 동안 소화기 의사가 알아야 할 사항

Review

Published on 2021-09-012022-09-11
Journal: Digestive diseases and sciences [Category] SARS, 치료기술,

Multi-Organ Histopathological Changes in a Mouse Hepatitis Virus Model of COVID-19

Article

Published on 2021-08-272022-10-28
Journal: Viruses [Category] COVID-19, MERS, SARS,

[키워드] alveolar animal model Asymptomatic Blood blood vessels Brain bronchiolar capillary cause Cell change changes characterized cortical COVID-19 COVID-19 pandemic Cytokine storm death distal edema epithelial hemorrhage Hemorrhagic Hepatitis Human humans hyaline membrane formation infect Infection infiltration inoculated interstitial interstitial tissue intra-alveolar liver macrophages mechanism mice Mild Model moderate mononuclear cell mouse mouse hepatitis virus-1 multiorgan histopathology Necrosis necrotic necrotic debris Neuron nuclei organ system oxidative stress pathophysiologic peribronchiolar perivascular Pneumonia precipitated red blood cells renal reported representing Respiratory illness responsible Safe SARS-CoV-2 SARS-CoV-2 infected individual SARS-COV-2 infection Septic shock severe lung inflammation severe symptom therapeutic interventions thrombosis thrombotic event Tubular Necrosis uninfected vascular congestion vascular defect vessels virus was used weight loss widespread
[DOI] 10.3390/v13091703 PMC 바로가기 [Article Type] Article

D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with COVID-19

COVID-19 예후 평가를위한 바이오 마커로서의 D-Dimer : COVID-19를 가진 입원 환자에서 입원 및 질병 결과를 예측하는 데있어서 D-Dimer 수준.

Research Article

Published on 2021-08-262022-08-13
Journal: PLoS ONE [Category] Biochemistry, MERS, SARS, 바이오마커,

[키워드] 95% CI Accuracy adjusted Admission age an area analyzed Biomarker calculate characteristic clinical confirmed COVID-19 case coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 patients Cox proportional hazard Cox proportional hazards regression analysis Cutoff cutoff value D-dimer D-dimer level D-dimer value determine died dimer disease Elevation fibrinogen Fibrinogen Equivalent Unit hazard ratio hospital Hospital mortality Hospital stay hospitalized patient hospitals in Kathmandu immunofluorescence assay laboratory parameter Laboratory parameters Mortality on admission outcome Patient patients with COVID-19 poor prognosis predict Predictive Predictive value Prognosis receiver operating characteristic receiver operating characteristic curve recorded regression analysis reported respiratory Respiratory illness Result ROC Curve sensitivity specificity surviving patient surviving patients thrombotic disorders two group two groups was measured was used with COVID-19
[DOI] 10.1371/journal.pone.0256744 PMC 바로가기 [Article Type] Research Article

Pollen antigens and atmospheric circulation driven seasonal respiratory viral outbreak and its implication to the Covid-19 pandemic

꽃가루 항원 및 대기 순환 구동 계절적 호흡기 바이러스 성 발병 및 Covid-19 Pandemic에 미치는 영향

Article

Published on 2021-08-202022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 진단,

Pharmacophore-Based Virtual Screening, Quantum Mechanics Calculations, and Molecular Dynamics Simulation Approaches Identified Potential Natural Antiviral Drug Candidates against MERS-CoV S1-NTD

Article

Published on 2021-08-172022-10-30
Journal: Molecules [Category] COVID-19,

[키워드] ADME Analysis antiviral drug Arabian Peninsula binding free energy binding site Bioactivity blocking candidate cause Compound compounds coronavirus DFT docking drug Dynamics effective evaluated exhibited facilitate Fatality rate FMO Homo host protein Human human host cells Identified identify Initially LUMO Mechanics MERS-CoV Middle East MM/GBSA molecular molecular docking molecular dynamics Molecular dynamics simulation N-terminal domain natural natural antiviral NTD pathogen performed pharmacophore modeling Potential predicted Protein quantum quantum mechanical calculation reactivity recognize reported Respiratory illness respiratory syndrome coronavirus retrieved S1 subunit S1-NTD Screening selected Simulation Sophoricoside stability Support Toxicity variety Virtual screening virus zoonotic
[DOI] 10.3390/molecules26164961 PMC 바로가기 [Article Type] Article

Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals

Article

Published on 2021-08-122022-10-28
Journal: Viruses [Category] COVID-19, MERS, SARS,

Plant-produced SARS-CoV-2 receptor binding domain (RBD) variants showed differential binding efficiency with anti-spike specific monoclonal antibodies

Research Article

Published on 2021-08-112022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] ACE2 acute respiratory syndrome Anti-spike Beta binding binding affinity binding domain binding efficiency characterized contrary convalescent coronavirus disease Coronavirus-2 COVID-19 CR3022 death ELISA enzyme exhibited Host host cell receptor increase in mAb mAbs monoclonal antibody Mutation neutralization neutralizing antibody Nicotiana benthamiana other variants pandemic produced raise RBD RBD-Fc receptor reported required Respiratory illness responsible SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 RBD protein SARS-CoV-2 receptor sera severe pneumonia South Africa strain suggested the spike protein transient expression United Kingdom vaccinated individual variant
[DOI] 10.1371/journal.pone.0253574 PMC 바로가기 [Article Type] Research Article

Paradigm Shift in Antimicrobial Resistance Pattern of Bacterial Isolates during the COVID-19 Pandemic

Article

Published on 2021-08-072022-10-27
Journal: Antibiotics [Category] COVID-19,

[키워드] antibiotic antibiotic use Antibiotics antimicrobial antimicrobial resistance Bacterial bacterial co-infection bacterial pathogen Blood blood sample Care clinician COVID-19 COVID-19 cases COVID-19 pandemic COVID-19 patient Department develop Escherichia coli evaluate help highlight hospital Hospital staff Hospitalized hospitals ICU ICUs IMPROVE increase in India infection control investigated irrational consumption isolate isolates maintain mechanism medication Microbiology MRSA negative observé occurred pandemic paradigm pathogen Pathogens patients with SARS-CoV-2 pattern positive processed public health resistance Respiratory illness shift single-center study Staphylococcus Staphylococcus aureus Surveillance Urine use of antibiotics
[DOI] 10.3390/antibiotics10080954 PMC 바로가기 [Article Type] Article

Therapeutic development by repurposing drugs targeting SARS-CoV-2 spike protein interactions by simulation studies

Research article

Published on 2021-08-012022-10-05
Journal: Saudi Journal of Biological Sciences [Category] 신약개발,

[키워드] affected Analysis antiviral drugs binding energy conducted Corona COVID-19 COVID-19 disease deviation docking Doxorubicin drug drugs drugs targeting evaluate Exemestane fluctuation Gatifloxacin gyration host cell Hydrogen bond in silico inhibit Interaction Interpretation MDs molecular interaction Molecular simulation pandemic pathogenic Prevent radius RBD complex reference Research respiratory Respiratory illness RMSD RMSF root SARS-CoV-2 SARS-CoV-2 spike protein Simulation study Spike protein Spread square suggested the SARS-CoV-2 therapeutic molecules transmitted virus spike protein Wuhan, China
[DOI] 10.1016/j.sjbs.2021.04.057 [Article Type] Research article

Systematic Network and Meta-analysis on the Antiviral Mechanisms of Probiotics: A Preventive and Treatment Strategy to Mitigate SARS-CoV-2 Infection

프로바이오틱스의 항바이러스 메커니즘에 대한 체계적인 네트워크 및 메타 분석: SARS-CoV-2 감염을 완화하기 위한 예방 및 치료 전략

Comment

Published on 2021-08-012022-09-11
Journal: Probiotics and antimicrobial proteins [Category] SARS, 유전자 메커니즘, 치료제,

[키워드] Activation affecting Analysis association biological network Biological network analysis boosting immunity candidate gene Clinical outcome common cold Comorbidities concerning country COVID-19 deaths domain functional Glucose Gut gut microbiome gut microbiota gut-lung axis Immune cell immune system immunomodulatory Immunosuppressed implementation IMPROVE individuals with COVID-19 infect infected case infected cases lung cells Lung infection lung tissue Meta-analysis metabolic pathway Microbiome Migration modulating molecular target network NLRP3 offer pandemic Pathway enrichment analysis Pathways Pneumonia Probiotics Prognosis rationale Respiratory illness resulting SARS-CoV-2 severity shown specific treatment Strategy systemic immune response the disease therapeutic effect therapeutic effects therapeutic strategy treating COVID-19 Treatment viral infection virus virus entry with COVID-19
[DOI] 10.1007/s12602-021-09748-w PMC 바로가기 [Article Type] Comment