RIG-I and TLR3 are both required for maximum interferon induction by influenza virus in human lung alveolar epithelial cellsArticle Published on 2015-08-012023-06-24 Journal: Virology [Category] 신종인플루엔자, [키워드] A549 AEC Human Influenza Innate immunity interferon lung PR8 RIG-I TLR3 [DOI] 10.1016/j.virol.2015.03.048 PMC 바로가기
Muscovy duck retinoic acid-induced gene I (MdRIG-I) functions in innate immunity against H9N2 avian influenza viruses (AIV) infectionsArticle Published on 2015-02-152023-06-02 Journal: Veterinary Immunology and Immunopathology [Category] 조류인플루엔자, [키워드] DF-1 H9N2 IFN-β innate immune response Muscovy duck RIG-I [DOI] 10.1016/j.vetimm.2014.12.009
Function of duck RIG-I in induction of antiviral response against IBDV and avian influenza virus on chicken cellsArticle Published on 2014-10-132023-06-02 Journal: Virus research [Category] 조류인플루엔자, [키워드] Apoptosis H9N2 IBDV RIG-I [DOI] 10.1016/j.virusres.2014.07.028
SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complexResearch Article Published on 2014-03-142022-10-29 Journal: Protein & Cell [Category] Coronavirus, [키워드] activated Activation antagonistic antiviral activity complex component deubiquitinase develop disrupt domain elicit evade explain expression form host innate immunity IFN IFN response IKKε inhibit interact Interaction interferon IRF3 mechanism Papain-like protease pathway Phosphorylation physically PLPro previous study reduce regulate RIG-I robust SARS Coronavirus SARS-CoV signaling pathway STING-TRAF3-TBK1 complex suggested TBK1 TRAF3 Type I IFN type I interferon yielding [DOI] 10.1007/s13238-014-0026-3 PMC 바로가기 [Article Type] Research Article
Regulation of macrophage and dendritic cell function by pathogens and through immunomodulation in the avian mucosaReview Published on 2013-11-012023-06-02 Journal: Developmental and comparative immunology [Category] 조류인플루엔자, [키워드] (Draining) lymph nodes Ag AIV Antigen antigen-presenting cells APC Avian influenza virus BALT BM Bone marrow bronchus-associated lymphoid tissue C-type lectin receptors CG chicken galectin chicken lung lectin CLL CLR DC DC-SIGN DC-specific intercellular adhesion molecule-3-grabbing non-integrin dendritic cells DLN GALT gut-associated lymphoid tissue HA Haemagglutinin highly-pathogenic avian influenza HPAI IAV IBDV IBV immunomodulation Infection Infectious Bronchitis Virus infectious bursal diease virus influenza A virus laboratory of genetics and physiology 2 LGP2 lipopolysaccharide Low pathogenic influenza LPAI LPS macrophage galactose binding lectin macrophage mannose receptor macrophages MDA5 Melanoma differentiation-associated protein 5 MGL MMR MPh mucosal NA NALT nasal associated lymphoid tissue NDV neuraminidase newcastle disease virus Pattern recognition receptors PRR respiratory tract retinoic acid-inducible gene I RIG-I Rt TLR Toll-like receptors [DOI] 10.1016/j.dci.2013.03.008 [Article Type] Review
Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: Hide, mask, hitArticle Published on 2013-10-122023-08-30 Journal: Antiviral Research [Category] E형 간염, [키워드] Innate immune system evasion Interferon alpha/beta LGP2 MDA5 RIG-I Viral dsRNA detection [DOI] 10.1016/j.antiviral.2013.10.002 PMC 바로가기 [Article Type] Article
Avian influenza virus H5N1 induces rapid interferon-beta production but shows more potent inhibition to retinoic acid-inducible gene I expression than H1N1 in vitroResearch Published on 2012-08-032023-06-07 Journal: Virology Journal [Category] 신종인플루엔자, [키워드] avian influenza virus H5N1 Interferon-beta RIG-I [DOI] 10.1186/1743-422X-9-145 PMC 바로가기 [Article Type] Research
Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated SignalingResearch Article Published on 2012-02-012022-10-06 Journal: PLoS ONE [Category] 진단, [키워드] Activation acute respiratory syndrome Antiviral block catalytic catalytically active Cell cells complex complexes contributing to coronavirus CoV Defense disrupting Disruption domain Endoplasmic reticulum evade expressing expression form found HCoV-NL63 Host IFN IKKε inactive Infected inhibit Innate innate immune innate immune response interferon MAVS mechanism membrane mutant NL63 nuclear translocation Papain-like protease PLP promoters Protein reduced regulate required response RIG-I SARS-CoV Signaling signaling molecule subsequent TBK1 wild type [DOI] 10.1371/journal.pone.0030802 PMC 바로가기 [Article Type] Research Article