SARS-CoV-2 evolution – Page 9 – Communicable Diseases Research

Stability of SARS-CoV-2 phylogenies

SARS-CoV-2 계통발생의 안정성

Research Article

Published on 2020-11-182022-08-13
Journal: PLoS Genetics
[Category] COVID-19, Medicine and Health Sciences, SARS,

[키워드] Affect building clade collected Community comparison Comparisons develop discourse effort Evolutionary inference evolutionary inferences evolutionary relationship evolutionary relationships excess facilitate feature genome sequence Genome sequences groups Host host viral genome editing identified variant Inclusion lab local lineage tracing molecular molecular and bioinformatic techniques mutations natural selection phylogenetic inference phylogenies Phylogeny primer binding site primer binding sites problematic variant problematic variants processing produced protein-coding sequence protein-coding sequences provided real-time genetic tracing Recombination recurrent mutation reported SARS-CoV-2 evolution SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 pandemic SARS-CoV-2 phylogenies SARS-CoV-2 phylogeny Scientific community screened sequence Sequencing sequencing error stable clade structure systematic errors the SARS-CoV-2 These data toolkit variant variants variety Viral viral genome viral lineages viral recombination viral sample viral samples Visualization
[DOI] 10.1371/journal.pgen.1009175 PMC 바로가기 [Article Type] Research Article

Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area

Research Article

Published on 2020-10-302022-10-29
Journal: mBio
[Category] COVID-19, MERS, SARS,

[키워드] acute respiratory syndrome Amino acid amino acid replacement amino acid replacements Analysis architecture Area caused Community coronavirus coronavirus disease COVID-19 COVID-19 disease CR3022 defined Diagnosis disease disease severity Evidence Evolution Features future infection generate Genome Genome sequencing genomic genomic data Genotype help host genetics Host immune response Houston Infection infections initial introduced Major massive Medical conditions molecular molecular population genomics monoclonal antibody nasopharynx Neutralizing pandemic Patient polymorphism produced provide Receptor binding domain Region SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 strain second second wave sequenced significantly higher Spike protein strain subsequent the SARS-CoV-2 the spike protein therapeutic trajectory Transmission Vaccine variant virulence virus virus virus genotype virus load Wave
[DOI] 10.1128/mBio.02707-20 PMC 바로가기 [Article Type] Research Article

Benchmarking evolutionary tinkering underlying human–viral molecular mimicry shows multiple host pulmonary–arterial peptides mimicked by SARS-CoV-2

Article

Published on 2020-10-022022-10-04
Journal: Cell Death Discovery
[Category] 유전자 메커니즘,

Genetic grouping of SARS-CoV-2 coronavirus sequences using informative subtype markers for pandemic spread visualization

전염병 확산 시각화를 위한 유익한 하위 유형 마커를 사용한 SARS-CoV-2 코로나바이러스 서열의 유전적 그룹화

Research Article

Published on 2020-09-172022-08-13
Journal: PLoS Computational Biology
[Category] SARS, 유전자 메커니즘,

[키워드] added addition Analysis analysis Applying Asia Author base cause Clustering complementary confirmed case Containment strategy COVID-19 COVID-19 pandemic D614G detect disease spread distribution downstream analyses effective efficient epidemiological studies Epidemiological study Europe followed by founder effect Frequency frequency analysis generate Genetic Genetic variant genetic variants Geographic distribution GISAID GISAID database Github highlight identify include increasingly individuals infected individual infected individuals information Local Major marker modeling Mutation New York Nextstrain Novel coronavirus nucleotide nucleotides ORF1ab outbreak pandemic Phylogenetic prevalent researcher responsible SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 evolution SARS-CoV-2 pandemic SARS-CoV-2 sequence SARS-CoV-2 sequences selection pressure sequence sequenced spatiotemporal Spike protein Spread subtype Subtypes temporal dynamics the spike protein the United State The United States therapeutic threshold United States utility Vaccine variant Viral viral dynamics viral genome viral genomes Viral transmission virus Visualization website
[DOI] 10.1371/journal.pcbi.1008269 PMC 바로가기 [Article Type] Research Article

Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets

Comparative Study

Published on 2020-07-102022-10-05
Journal: Nature Microbiology
[Category] SARS, 진단,

Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting

Article

Published on 2020-07-072022-10-29
Journal: International Journal of Molecular Sciences
[Category] COVID-19, SARS,

[키워드] addition Affect Alter amino acid changes analysed cardiovascular disease changes in conserved conserved mutation Critical expressed Genome genomic globe host cells host miRNA host miRNAs human host humans interfere introduced microRNA miRNA miRNA target Mutation mutations offer overexpressed pathogen Pathogenesis Patient platform predicted Replication RNA RNA secondary structure SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 isolate SARS-CoV-2 replication SARS-CoV-2 virus secondary structure secondary structures sequence splice site Structure subset target targeting the SARS-CoV-2 Transmission Vaccine development viral fitness viral life cycle viral tropism zoonotic
[DOI] 10.3390/ijms21134807 PMC 바로가기 [Article Type] Article

Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site

Research Article

Published on 2020-07-032022-10-31
Journal: Emerging Microbes & Infections
[Category] COVID-19, MERS, SARS,

Phylogenetic network analysis of SARS-CoV-2 genomes

530

Published on 2020-04-282022-10-29
Journal: Proceedings of the National Academy of Sciences of
[Category] COVID-19, SARS,