Severe vivax malaria: a systematic review and meta-analysis of clinical studies since 1900심각한 비바스 말라리아: 1900년 이후의 임상 연구에 대한 체계적 검토 및 메타 분석Research Published on 2014-12-082024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Complication malaria Meta-analysis Plasmodiumvivax Prevalence severe systematic review [DOI] 10.1186/1475-2875-13-481 PMC 바로가기 [Article Type] Research
A descriptive study of 16 severe Plasmodium vivax cases from three municipalities of Colombia between 2009 and 20132009년부터 2013년까지 콜롬비아의 세 개 지방자치단체에서 발생한 16건의 중증 플라스모디움 비박스 사례에 대한 기술적 연구Research Published on 2014-10-152024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Colombia Plasmodium vivax severe [DOI] 10.1186/1475-2875-13-404 PMC 바로가기 [Article Type] Research
Plasmodium ovale : a case of not-so-benign tertian malaria플라스모디움 오발레: 그리 benign하지 않은 삼일열 말라리아의 사례Case Report Published on 2014-03-102024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Infection malaria Plasmodium ovale severe [DOI] 10.1186/1475-2875-13-85 PMC 바로가기 [Article Type] Case Report
Bayesian Reconstruction of Disease Outbreaks by Combining Epidemiologic and Genomic DataResearch Article Published on 2014-01-232022-10-28 Journal: PLoS Computational Biology [Category] Coronavirus, MERS, [키워드] 2003 After Analysis approach Author Bayesian caused Containment strategy detect disease DNA early stage Epidemic Epidemics epidemiological event events genetic data genome sequence Genome sequences heterogeneous identify IMPROVE Infected infections Infectious disease information Making methodological one individual outbreak Outbreaks pathogen R package recent reconstruction respiratory Secondary infection sequence severe statistical statistically subsequent subsequent infections super-spreaders the disease Transmission transmitted understanding variety [DOI] 10.1371/journal.pcbi.1003457 PMC 바로가기 [Article Type] Research Article
Randomized Controlled Trial of Levamisole Hydrochloride as Adjunctive Therapy in Severe Falciparum Malaria With High Parasitemia심한 열대열 말라리아에서 고수치 기생충 감염에 대한 보조 요법으로서 레바미졸 염산염의 무작위 대조 시험Article Published on 2014-01-012024-08-13 Journal: Nanoscale [Category] 말라리아, [키워드] artesunate Falciparum Levamisole malaria sequestration severe [DOI] 10.1093/infdis/jit410 PMC 바로가기
In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infectionShort Report Published on 2013-12-232022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] acute renal failure Angiotensin-converting-enzyme-2 ARF benefit bronchial epithelial cell bronchial epithelial cells Case report cause Cell cell type cells cellular receptor Characteristics Comparative description Dipeptidyl-peptidase-4 epithelial epithelial cell epithelial cells experiment explain finding histological staining human coronavirus human kidney impairment individual Infected Infection infections infectious kidney kidney infection median time MERS MERS patient MERS-CoV Middle East Middle East respiratory syndrome occurred Patient peer-reviewed potential mechanism produced progeny renal Renal epithelial cells Replication respiratory reveal SARS patients SARS- and MERS-CoV SARS-CoV SD severe staining Symptom systematic review Transmission Treatment Urine [DOI] 10.1186/1743-422X-10-359 PMC 바로가기 [Article Type] Short Report
Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential TherapeuticsResearch Article Published on 2013-08-152022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] 5-FU activity antiviral activity antiviral drug Author biochemical Combination compared conserved coronavirus CoV CoV replication CoVs Critical decrease demonstrated determine Epidemic Evidence Exoribonuclease Express Genetic high mutation rate human coronavirus human disease Hypothesis identify increase in inhibitor inhibitory activity lethal MERS-CoV Middle East Mutagenesis Mutation Next-generation sequencing NO nonstructural protein 14 nsp14-ExoN nucleotides Population Potential Prevent Probability Proofreading provide RdRP Replication required respiratory responsible ribavirin RNA RNA synthesis RNA virus SARS-CoV selective sensitivity severe Support susceptible target Therapeutics to define treated Vaccine viral adaptation Viral protein viral RNA synthesis virus virus replication while wild-type zoonotic [DOI] 10.1371/journal.ppat.1003565 PMC 바로가기 [Article Type] Research Article
A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory VirusesResearch Article Published on 2013-07-252022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] approach both virus component conserved Critical dataset disease pathology effort epithelial cell event Factor feature Gene Host host response human lung identify Infection influence Influenza virus integration Interaction Intervention involved lung epithelial Metrics network Pandemics pathogen pathogenicity predict predicted proteome public health threat Regression model regulator Regulatory related respiratory respiratory virus SARS-CoV severe therapeutic target transcriptome dataset utility viral pathogenesis virus [DOI] 10.1371/journal.pone.0069374 PMC 바로가기 [Article Type] Research Article
Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations세 아프리카 인구에서 심각한 말라리아의 대치 기반 메타 분석Research Article Published on 2013-05-232022-09-12 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] Affect affected African allele alleles Analysis approach association assumption Author Bayesian approach Bayesian approaches Blood blood type cause Cell children Community complex conducted confounding effect Control country detect different disease DNA variant ethnic group Ethnic groups Europe European feasibility fixed genes ABO genetic diversity genetic risk factor genetic risk factors genetics Genome-wide association studies Genome-wide association study genome-wide data genomic location genotype imputation GWAS Haemoglobin Haplotype HBB healthy individual heterogeneity heterogeneous individual Kenya kill location malaria malaria susceptibility loci Meta-analysis multicentre observation Population populations risk S allele Sample size sample sizes severe severe malaria sickle cell Sickle cell disease sickle cell disease) statistical model statistical test Statistical tests strength [DOI] 10.1371/journal.pgen.1003509 PMC 바로가기 [Article Type] Research Article
Identifying SARS-CoV Membrane Protein Amino Acid Residues Linked to Virus-Like Particle AssemblyResearch Article Published on 2013-05-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] acid acute respiratory syndrome addition affected Amino acid amino acid residue analyses Analysis assembly codon coexpressed Combined conserved coronavirus Critical cysteine residue ectodomain endodomain identify identifying Interaction involved membrane motif mutant Mutation nucleocapsid Particle Protein reduced reduction in regions required residue Result SARS-CoV SARS-CoV virus secretion sequence Serine severe significantly Substitution transmembrane vesicles virus Virus-like particle VLP VLPs [DOI] 10.1371/journal.pone.0064013 PMC 바로가기 [Article Type] Research Article