Real-life use of tocilizumab with or without corticosteroid in hospitalized patients with moderate-to-severe COVID-19 pneumonia: A retrospective cohort study중등도에서 중증 COVID-19 폐렴으로 입원한 환자에서 코르티코스테로이드 유무에 관계없이 토실리주맙의 실제 사용: 후향적 코호트 연구Research Article Published on 2021-09-102022-09-12 Journal: PLoS ONE [Category] 진단, [키워드] Administered administration of corticosteroid affected age Analysis baseline clinical trials Comorbidities Comorbidity conducted Corticosteroid Corticosteroids COVID-19 COVID-19 pneumonia death Effectiveness efficacious therapeutic Efficacy evaluate evaluated Factors First wave hospital Hospital admission Hospitalized hospitalized patient Infectious disease intubation Invasive mechanical ventilation Italy Lazio median median time men Mild moderate moderate-to-severe COVID-19 moderate-to-severe COVID-19 patient moderate-to-severe COVID-19 patients moderate-to-severe COVID-19 pneumonia Multivariate analysis objective outcome Patient Pneumonia primary and secondary outcomes protective effect randomized clinical trial recruited Result retrospective cohort study risk Safe SARS-CoV-2 pandemic secondary outcome Severe case severe cases Severe COVID-19 pneumonia SOC Standard of care symptom onset the median Tocilizumab Treatment were recorded [DOI] 10.1371/journal.pone.0257376 PMC 바로가기 [Article Type] Research Article
Case Report: Potential Role of Corticosteroids in the Management of Post-COVID-19 PneumoniaMedicine Published on 2021-09-092022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] accelerated activities acute respiratory distress Admission ARDS benefit characterized chest CT scan clinical symptom clinically complex coronavirus disease Corticosteroid corticosteroid therapy cough COVID-19 discharge discharged home dose Dyspnea Follow-up high-flow oxygen therapy Hospitalized immune reaction Inflammatory initial intensive care interstitial Interstitial lung diseases Lung disease lung lesions management Organizing pneumonia outcome oxygen Oxygen therapy Patient performed Pneumonia post-COVID-19 infection Potential pulmonary lesions required role SARS-CoV-2 PCR test Severe COVID-19 pneumonia severe pneumonia severity subject symptomatic symptomatic improvement syndrome the patient treated Withdrawal [DOI] 10.3389/fmed.2021.686806 PMC 바로가기 [Article Type] Medicine
The Role of Noninvasive Respiratory Management in Patients with Severe COVID-19 PneumoniaReview Published on 2021-09-032022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] close monitoring Complication COVID-19 COVID-19 disease death employment Endotracheal intubation Evidence healthcare personnel HFNO High flow nasal oxygen Hospitalization hypoxemic implementation intensive care unit intubated patient intubation Invasive mechanical ventilation NIV noninvasive respiratory treatment Noninvasive ventilation Oxygen treatment pandemic era Patient Precaution PROTECT reducing respiratory Respiratory failure respond risk role SARS-CoV-2 severe COVID-19 Severe COVID-19 Infection Severe COVID-19 pneumonia severe hypoxemia sparing Viral transmission with COVID-19 [DOI] 10.3390/jpm11090884 PMC 바로가기 [Article Type] Review
Interstitial Lung Disease at High Resolution CT after SARS-CoV-2-Related Acute Respiratory Distress Syndrome According to Pulmonary Segmental AnatomyArticle Published on 2021-09-022022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress syndrome affected alteration ARDS average changes consecutive patient consolidation consolidations correlated Corticosteroid COVID-19 pneumonia CT finding CT scan demographic data described Diagnosis discharge distribution enrolled evaluate evaluated GGO GGOs Ground glass opacity high resolution computed tomography hospital discharge hospitalised HRCT Laboratory linear low-dose lower lobe lung median time Methylprednisolone Patient pulmonary pulmonary fibrosis pulmonary parenchyma Resolution respiratory Retrospective study Segmental Severe COVID-19 pneumonia spirometry survivor treated Volume [DOI] 10.3390/jcm10173985 PMC 바로가기 [Article Type] Article
Pulmonary function and six-minute-walk test in patients after recovery from COVID-19: A prospective cohort studyCOVID-19 회복 후 환자의 폐 기능 및 6분 걷기 검사: 전향적 코호트 연구Research Article Published on 2021-09-022022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] 6MWT abnormality age BMI body mass body mass index Chest Chest radiograph chest radiographs conducted confirmed case coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia COVID-19 pneumonia patient discharged fibrosis Follow-up FVC group groups hospital majority medical school men Mild Mild symptom mild symptoms objective Obstructive onset of symptoms Patient Pneumonia prevalence rate prospective cohort study pulmonary Result Severe COVID-19 pneumonia severe pneumonia spirometry statistically significant Study design survivor Symptom the mean the patient walking distance women [DOI] 10.1371/journal.pone.0257040 PMC 바로가기 [Article Type] Research Article
Antiviral treatment could not provide clinical benefit in management of mild COVID-19: A Retrospective Experience from Field hospital항바이러스 치료는 경증 COVID-19 관리에 임상적 이점을 제공할 수 없음: 현장 병원의 회고적 경험Article Published on 2021-09-012022-09-11 Journal: Journal of infection and public health [Category] SARS, 치료법, 치료제, [키워드] 95%CI abdominal pain acute respiratory distress acute respiratory distress syndrome Adverse drug reaction Adverse drug reactions affected age Antiviral antiviral drug antiviral drugs antiviral medication Antiviral treatment antiviral treatments Asymptomatic caused clinical benefit Clinical outcome clinical outcomes Complication coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 pneumonia Critical darunavir Darunavir-ritonavir death demonstrated diagnosed with COVID-19 diarrhea discharged home Disease progression evaluated experience Favipiravir field hospital Hepatitis hospital Hospital stay IQR Laboratory results Lopinavir Lopinavir-ritonavir Lopinavir/ritonavir males management median medical history Mild mild COVID-19 patient mild COVID-19 patients moderate past medical history Patient patients with asymptomatic Positive test receiving regimen respiratory distress Ritonavir Severe COVID-19 pneumonia significantly Standard standard supportive care supportive care Supportive treatment syndrome Treatment Treatment outcome university [DOI] 10.1016/j.jiph.2021.07.019 PMC 바로가기 [Article Type] Article
Evaluation of long-term radiological findings, pulmonary functions, and health-related quality of life in survivors of severe COVID-19중증 코로나19 생존자의 장기 방사선 소견, 폐 기능 및 건강 관련 삶의 질 평가Article Published on 2021-09-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료기술, [키워드] 6MWT applied changes in Chest computed tomography Chest CT Computed tomography coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 pneumonia discharge evaluate evaluated expected female patient fibrosis forced expiratory volume forced vital capacity functions Health health parameter hospital interstitial lung lung involvement male Pain Pathogenesis Patient patients physical problem Psychology pulmonary fibrosis Pulmonary function Quality of life radiological radiological abnormalities radiological abnormality respiratory tract severe coronavirus disease severe COVID-19 Severe COVID-19 pneumonia social science spirometry survivor virus virus classification vital capacity was performed [DOI] 10.1002/jmv.27101 PMC 바로가기 [Article Type] Article
Biomarkers of severe COVID-19 pneumonia on admission using data-mining powered by common laboratory blood tests-datasets일반적인 실험실 혈액 검사 데이터 세트로 구동되는 데이터 마이닝을 사용하여 입원 시 중증 COVID-19 폐렴의 바이오마커Article Published on 2021-09-012022-09-11 Journal: Computers in biology and medicine [Category] MERS, SARS, 바이오마커, [키워드] acid-base balance Admission Algorithm analyzed approach artificial intelligence best Biomarkers Blood blood gas Blood gas analyses C-reactive protein clinical laboratory Clinical laboratory techniques clinical outcomes Clustering complex conducted correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 pneumonia COVID-19 research Data mining dataset datasets Decision tree disease severity epidemiological feature fluctuation form Glucose group hematological Hemogram hidden Hierarchical high risk Hypoxemia Inflammation investigated involved knowledge Laboratory Laboratory tests leukocyte limitation lymphocyte machine machine learning Medical Informatics Applications neutrophil on admission PaO Pearson perceptron performed Pneumonia Precision predict processed Protein Prothrombin time R software severe severe COVID-19 Severe COVID-19 pneumonia severity skill supervised learning therapeutic targets unique variable [DOI] 10.1016/j.compbiomed.2021.104738 PMC 바로가기 [Article Type] Article
Cytokine storm in severe COVID-19 pneumonia심각한 COVID-19 폐렴의 사이토카인 폭풍Article Published on 2021-09-012022-09-11 Journal: Journal of medical virology [Category] SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome addition Alanine ALT Anemia anti-cytokine anti-cytokine therapy ARDS aspartate AST clinic Confirmed COVID-19 infection coronavirus COVID-19 COVID-19 infection COVID-19 patient COVID-19 pneumonia criteria Cytokine storm decrease determine develop disease elevated elevated lactate dehydrogenase feature ferritin help hemoglobin hemophagocytic lymphohistiocytosis Hospitalized Hyperferritinemia hyperfibrinogenemia Hyperinflammatory syndrome ICU ICU admission identify immnopathology immune immune responses in some include Inflammation intensive care intensive care unit Laboratory laboratory parameter Laboratory parameters Lactate lactate dehydrogenase LDH leukocyte Liver function Liver function test lymphocyte lymphocytopenia Macrophage macrophage activation syndrome Novel coronavirus occurred parameter parameters Patient patients Planning Platelet Pneumonia predict procalcitonin progression reduced respiratory distress Respiratory distress syndrome retrospective cohort study secondary hemophagocytic lymphohistiocytosis Severe COVID-19 pneumonia Severe patient severe pneumonia sHLH significant changes in significantly significantly increased Symptom syndrome the cytokine storm the patient thrombocytopenia transferred Triglyceride troponin two subgroups virus virus classification with COVID-19 worsened worsening [DOI] 10.1002/jmv.27068 PMC 바로가기 [Article Type] Article
The Angiotensin Converting Enzyme Deletion/Deletion Genotype Is a Risk Factor for Severe COVID-19: Implication and Utility for Patients Admitted to Emergency DepartmentObservational Study Published on 2021-08-202022-10-04 Journal: Medicina [Category] MERS, SARS, 임상, [키워드] ACE ACE2 activity affected age alteration angiotensin angiotensin converting enzyme Angiotensin-converting enzyme ARDS association caused Complication conducted correlated COVID-19 COVID-19 disease Department described distress Emergency Evolution Factor Genetic Genetic predisposition Genotype healthy controls hypothesised increase Italy majority marker material Mutation Naple observation outcome Patient performed Pneumonia polymorphism positive Prevalence Result risk risk factor SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe COVID-19 patient Severe COVID-19 pneumonia severity significantly higher subject syndrome tested the disease thrombosis unit Venous Thromboembolism VTE [DOI] 10.3390/medicina57080844 PMC 바로가기 [Article Type] Observational Study