Factors associated with anti-SARS-CoV-2 spike antibody titers after a second BNT162b2 mRNA COVID-19 vaccination in Japanese hemodialysis patients일본 혈액투석 환자에서 두 번째 BNT162b2 mRNA COVID-19 백신 접종 후 항-SARS-CoV-2 스파이크 항체 역가와 관련된 요인Article Published on 2022-09-012022-09-12 Journal: Clinical and experimental nephrology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome age Analysis anti-SARS-CoV-2 Anti-severe acute respiratory syndrome coronavirus 2 spike antibody Antibody titer Blood urea nitrogen BNT162b2 BNT162b2 messenger RNA vaccine BNT162b2 mRNA Concentration coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional determine disease enrolled Factor healthcare worker Hemodialysis hemoglobin investigated Japanese Lymphocyte count lymphocyte counts men Messenger RNA Multiple linear regression parameters Patient SARS-CoV-2 second dose severe acute respiratory syndrome coronavirus 2 significantly significantly lower single-center Vaccine [DOI] 10.1007/s10157-022-02223-y PMC 바로가기 [Article Type] Article
The Effects of Motivational Messages Sent to Emergency Nurses During the COVID-19 Pandemic on Job Satisfaction, Compassion Fatigue, and Communication Skills: A Randomized Controlled TrialResearch article Published on 2022-09-012022-10-05 Journal: Journal of emergency nursing [Category] 임상, [키워드] Administered affected age assigned communication Communication skills Compassion Compassion fatigue conducted control group control groups Controlled COVID-19 COVID-19 pandemic Effect Emergency Factor fatigue hospital IMPROVE Intervention intervention group Isolation İstanbul job Job satisfaction message motivation no significant difference Nurse Nursing participant physically psychologically Randomized Randomly reducing Research resources Result Satisfaction scale Sent significantly higher significantly lower skill [DOI] 10.1016/j.jen.2022.06.001 [Article Type] Research article
Long-term survival benefit of male and multimorbid COVID-19 patients with 5-day remdesivir treatmentObservational Study Published on 2022-08-312022-10-05 Journal: Journal of Global Health [Category] SARS, 변종, 임상, [키워드] all-cause mortality Alpha Analysis Anemia antiviral medication benefit center clinical condition Cohort collected Comorbidity COPD coronavirus disease Course covariates COVID-19 COVID-19 pandemic COVID-19 patient diabete effective Efficacy epidemiological situation Frequency greater group hospitalized patients Hungary Inpatient lack male men Mortality multiple comorbidities multivariate Observational cohort study outcome parenchymal participant Patient performed Primary outcome RDV real-world data receiving Remdesivir retrospective risk reduction Significant significantly lower significantly more specific patient groups Standard of care supplementary oxygen survival Treatment Treatment protocol treatment regimen university Vaccinations variant [DOI] 10.7189/jogh.12.05031 PMC 바로가기 [Article Type] Observational Study
Third Early “Booster” Dose Strategy in France of bnt162b2 SARS-CoV-2 Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients Enhances Neutralizing Antibody ResponsesArticle Published on 2022-08-302022-11-15 Journal: Viruses [Category] SARS, 변종, 진단, [키워드] administration allogeneic HSCT Anti-spike antibody Antibody Response Beta BNT162b2 vaccine booster Breakthrough infection can be used circulation correlated COVID-19 COVID-19 vaccine Delta delta variant dose enzyme France healthy hematopoietic high-risk population HSCT HSCT immunocompromised patients HSCT recipient humoral Humoral response immune immune protection Immune suppression immunoassay Immunocompromised immunocompromised individuals Immunocompromised patients Immunosuppressed individual marker monoclonal antibody Neutralization assay neutralization titer Neutralizing Neutralizing activity neutralizing antibody Neutralizing antibody response omicron preventive measure PROTECT Protein question raised recipient recipients response SARS-CoV-2 SARS-CoV-2 variant sensitivity significantly lower STEM Strategy Support tested the vaccine Transplant vaccination vaccine dose variant variant of concern variants [DOI] 10.3390/v14091928 PMC 바로가기
Viral RNA Load in Symptomatic and Asymptomatic COVID-19 Omicron Variant-Positive PatientsArticle Published on 2022-08-292022-11-16 Journal: Canadian Respiratory Journal [Category] SARS, 변종, [키워드] acute respiratory syndrome age Analysis Asymptomatic asymptomatic patient children coronavirus COVID-19 cycle threshold evaluate infected with SARS-CoV-2 load median nasal nasopharynx not differ omicron Patient patients PCR polymerase chain respiratory sample respiratory tract sample RNA SARS-CoV-2 significantly significantly lower strain symptomatic symptomatic and asymptomatic symptomatic patient the mean variant viral dynamics Viral load Viral transmission [DOI] 10.1155/2022/5460400 PMC 바로가기
A Long-Term Comparison of Presenting Characteristics of Children with Newly Diagnosed Type 1 Diabetes Before and During the COVID-19 PandemicArticle Published on 2022-08-252022-11-15 Journal: Journal of clinical research in pediatric endocrinology [Category] 진단, [키워드] Admission age antibody autoantibody C-peptide Characteristics Child childhood children Clinical characteristics Contact Coverage COVID-19 diabete diabetes Diabetes Mellitus Diabetic diabetic ketoacidosis diagnosed Diagnosis Diseases duration of symptom Frequency group healthcare service hemoglobin Hospital stay Infection investigated Laboratory less morbidity and mortality no difference not differ other disease other diseases pandemic Patient polymerase chain presenting provide raise raised risk severity Sex significantly higher significantly lower significantly shorter Symptom T1D T1D patient the patient Thyroid tissue Transmission two group Type type-1 diabetes. were recorded [DOI] 10.4274/jcrpe.galenos.2022.2021-10-2 PMC 바로가기
Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant by Sera From BNT162b2 or CoronaVac Vaccine RecipientsBNT162b2 또는 CoronaVac 백신 수혜자의 혈청에 의한 중증 급성 호흡기 증후군 코로나바이러스 2 오미크론 변이체의 중화Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody titer Antibody titers Beta Beta variant beta variants BNT162b2 CoronaVac coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine Delta variants detectable Effectiveness elicited evade genome sequence geometric geometric mean GISAID database GMT GMTs Health Organization isolate Lineage Live virus microneutralization Mutation Nanopore nanopore sequencing neutralization Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer no significant difference not affect of BNT162b2 omicron Omicron variant Patient recipient recipients respiratory risk Risk assessment SARS-CoV-2 Sequencing sera severe acute respiratory syndrome Coronavirus significant difference significantly lower spike mutation strain Strains susceptibility TMPRSS2 Vaccine Vaccines variant variant of concern VeroE6 cells virus was determined whole genome sequence World Health Organization [DOI] 10.1093/cid/ciab1041 PMC 바로가기 [Article Type] Article
Necessity of Coronavirus Disease 2019 (COVID-19) Vaccination in Persons Who Have Already Had COVID-19이미 COVID-19에 걸린 사람에 대한 코로나바이러스 질병 2019(COVID-19) 예방 접종의 필요성Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] 95% CI Cleveland clinic coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination Cox proportional hazard cumulative incidence demonstrated employee evaluate examined group groups Hospitalization hospitalizations Immunity incidence infected individual Infection lower risk mRNA vaccine multivariable Not demonstrated omicron Omicron variant Person positive provide receiving remained risk risk of COVID-19 SARS-CoV-2 second dose significantly lower subjects symptomatic symptomatic COVID-19 tested uninfected vaccination Vaccines variant [DOI] 10.1093/cid/ciac022 PMC 바로가기 [Article Type] Article
Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational studyResearch article Published on 2022-08-242022-10-05 Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] admitted to ICU Affect affecting Analysis Antwerp Aspergillus autophagy Belgium Bronchoalveolar lavage fluid bronchoalveolar lavage sample bronchoalveolar lavage samples calculate Cell chemokines collected Concentration conidia COVID-19 Critically ill patient Cytokines development diagnose differentially expressed disrupting downregulated downregulation elevated Eligible patients encoding protein enrichment analysis epithelial European expression expression data finding foundation fraction France function funding Gene expression analysis growth factor Horizon hospital hyphae ICU IFNγ IL-1β Immunity in vivo increased mortality Influenza Influenza virus Innate immunity intensive care invasive invasive ventilation investigated kill killing lung epithelial Max Planck Society network neutrophil Neutrophils Non-invasive pathophysiology pathway Pathway analysis Pathways Patient patients patients with COVID-19 patients with influenza performed phagocytosis Protein recruited Regional retrieved SARS-COV-2 infection SARS-CoV-2 RNA several gene significantly significantly lower spores TNF-α tracheobronchial transcriptomics Treatment Type I IFN type II IFN university University Hospitals Leuven were used [DOI] 10.1016/S2213-2600(22)00259-4 [Article Type] Research article
Prospective Evaluation of Coronavirus Disease 2019 (COVID-19) Vaccine Responses Across a Broad Spectrum of Immunocompromising Conditions: the COVID-19 Vaccination in the Immunocompromised Study (COVICS)광범위한 면역 손상 조건에 걸친 코로나바이러스 질병 2019(COVID-19) 백신 반응의 전향적 평가: 면역 손상 연구(COVICS)의 COVID-19 백신 접종Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome adenovirus vector vaccine age anti-CD20 antibody antibody level Antibody Response approach autoimmune condition autoimmune conditions BNT162b2 cause comparison coronavirus coronavirus disease correlated correlation COVID-19 COVID-19 vaccine COVID-19 vaccines domain Factor greater HCW HCWs healthcare worker Hematologic malignancy Hematological malignancy HIV Human immunodeficiency virus Humoral response identify Immunocompromised immunocompromised adult immunocompromised individual Immunocompromised patient immunodeficiency Immunoglobulin Immunosuppression Logistic regression lowest Messenger RNA Moderna monoclonal monoclonal antibodies mRNA-1273 neutralization titer neutralization titers outcome participant Pfizer Primary outcome proportion Prospective pseudovirus reactive recipient recipients response SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 neutralization secondary seropositive seropositive participant significantly lower solid cancers solid organ transplant solid tumor SOT Spearman Spectrum vaccination Vaccine was used [DOI] 10.1093/cid/ciac103 PMC 바로가기 [Article Type] Article