PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complexPRM1 및 KAR5는 세포-세포 융합 및 핵종에서 기능하여 Cryptococcus 병원성 종 복합체에서 뚜렷한 양성 및 단성 주기를 유도합니다Research Article Published on 2017-11-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence adaptation bisexual reproduction Cell Cell fusion cell-cell fusion cellular processe characterization characterized complex conserved Critical Cryptococcus Cryptococcus neoforman Cryptococcus neoformans de novo demonstrated diploid eukaryotic eukaryotic systems events Evolution forms fungal fungal pathogens fungi fusion protein generate Genetic genotypic hyphae hyphal independent individual involved isolate karyogamy mating type mechanism Morphological nuclear nuclear fusion nuclear membrane observation occur offset opposite organism ortholog orthologs pathogen pathogenic Pathogens pathway phenotypic diversity plants plasma membrane PRM1 produced regulate selfing sexual cycles sexual reproduction Sexuality similarities similarity Stage trajectory undergo yeast [DOI] 10.1371/journal.pgen.1007113 PMC 바로가기 [Article Type] Research Article
A Novel Highly Divergent Protein Family Identified from a Viviparous Insect by RNA-seq Analysis: A Potential Target for Tsetse Fly-Specific AbortifacientsRNA-seq 분석을 통해 태생 곤충에서 식별된 매우 다양한 새로운 단백질 패밀리: 체체 파리 관련 낙태 환자의 잠재적 표적Research Article Published on 2014-04-242022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Abortifacient addition African Amino acid amino acid sequence Analysis approaches casein cattle causative agents characterization coding control mechanisms Critical Differential analysis enrichment Factor family fecundity female functional genes encoding Genome genomic homeostasis Human Identified identify indicate insect Interference knockdown lactating lactation lipid metabolism maintenance mammalian mechanism mechanisms metabolism mother s milk novel occur organized Potential progeny Protein protein level protein synthesis Proteins proteome provided reduce reduced reducing Region reproductive resource RNA-Seq RNA-seq data secretion sequence similarity Seven shown similarities sleeping sickness specificity suppression synthesis target to define transcript Transcriptome transcripts Transferrin tsetse tsetse flies tsetse fly unique variant Viviparous were expressed while [DOI] 10.1371/journal.pgen.1003874 PMC 바로가기 [Article Type] Research Article
High-Resolution Transcriptome Maps Reveal Strain-Specific Regulatory Features of Multiple Campylobacter jejuni Isolates고해상도 전사체 지도는 여러 Campylobacter jejuni 분리주의 균주 특이적 조절 기능을 보여줍니다Research Article Published on 2013-05-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptation addition Analysis analyzed approach Author automated Bacterial bioinformatics Campylobacter Campylobacter jejuni compared consequence conservation conserved contribute CRISPR different DNA ecological niche ecological niches eukaryote eukaryotes facilitate feature functional gastroenteritis Gene Gene Expression Gene regulation Genetic Genome genome sequence Genome sequences genomic variation genomic variations genotypic genotypic variations growth Host hosts humans immune system IMPROVE include integration isolate isolates lead Map maturation modulate Multiple organism Organisms Pathogens pathway phenotypic phenotypic diversity phenotypic variation promoter promoter regions promoters provide Regulation related reveal RNA RNA sequencing RNase similarities similarity small RNA SNP sRNA strain Strains stress conditions time-consuming transcribed transcriptional Transcriptome transcriptomes TSS unique upstream Variation whole-genome [DOI] 10.1371/journal.pgen.1003495 PMC 바로가기 [Article Type] Research Article