Broad antiviral and anti‐inflammatory efficacy of nafamostat against SARS‐CoV‐2 and seasonal coronaviruses in primary human bronchiolar epitheliaResearch Article Published on 2021-06-302022-10-29 Journal: Nano Select [Category] COVID-19, [키워드] Activation airway epithelia airway epithelium anti‐inflammatory Antiviral antiviral activity antiviral effects antiviral property block bronchiolar Cell chronic obstructive COVID‐19 cytokine Donor Effect Efficacy epithelia epithelial cell evaluate exhibit healthy donors help Host host protease host serine protease human coronaviruses human coronaviruses 229E independent infect Inflammation inhibit log mitigate nafamostat Nafamostat mesylate observé Pathogenesis primary human airway pulmonary disease reduce reduction Replication respiratory infection SARS‐CoV‐2 SARS‐CoV‐2 seasonal coronavirus serine protease inhibitor smoker subject therapeutic therapeutic potential TMPRSS2 Treatment viral spike protein virus infection [DOI] 10.1002/nano.202100123 PMC 바로가기 [Article Type] Research Article
The Impact of COVID-19 on Smoking Behaviours and Support for Smoke-Free Zones in Saudi ArabiaArticle Published on 2021-06-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] affected analysed Analysis barriers for quitting COVID-19 COVID-19 pandemic Express help highlighting Impact Jeddah limitation media participant quitting tobacco products reductions in response retrospective Saudi Arabia secondhand smoking smoke free zones smoker smoking smoking cessation Support university widespread zone [DOI] 10.3390/ijerph18136927 PMC 바로가기 [Article Type] Article
Influenza vaccination coverage in elderly and high-risk adults: characterization of associated factorsOriginal Article Published on 2021-06-282022-10-31 Journal: Einstein [Category] Coronavirus, SARS, [키워드] Adults analyzed Barreiras ao acesso aos cuidados de saúde Barriers to access of health services carried coronavirus 2019 disease Coverage COVID-19 cross-sectional defined demographic Depressive symptoms evaluate Factor group grupos de risco Health Service Health services research hospital individual Influenza influenza vaccination influenza vaccines Mortality objective outcome participated pelo coronavírus Pesquisa sobre serviços de saúde physical activity pregnant women Prevalence Prevenção primária Primary prevention public health Result Rio Grande risk risk groups saúde pública similarity smoker vaccination Vacinas contra influenza variables [DOI] 10.31744/einstein_journal/2021AO5830 PMC 바로가기 [Article Type] Original Article
SARS-Co-V2 infection in never, former, and current tobacco/nicotine users: a cohort study of 4040 Egyptian healthcare workersResearch Published on 2021-06-282022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] adjusted adverse outcomes Analysis analyzed association baseline Cairo Characteristics co-morbidities Cohort cohort study confounder country COVID-19 COVID-19 case COVID-19 severity demographics Egypt Evidence examined Follow-up Frequency HCW HCWs healthcare facility healthcare worker Healthcare workers Impact Infection multivariable logistic regression Nicotine performed positive Positive test Prevalence Previous studies proportion prospective cohort study Result risk SARS-Co-V2 SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 tests significantly smoker smoking Study design supplementary material Symptom Symptoms Tobacco took place [DOI] 10.1186/s12889-021-11290-x PMC 바로가기 [Article Type] Research
SARS-CoV-2 serology in 4000 health care and administrative staff across seven sites in Lombardy, Italy이탈리아 롬바르디에있는 7 개 사이트에 걸친 4000 명의 건강 관리 및 행정 직원의 SARS-COV-2 혈청학Clinical Trial Published on 2021-06-102022-08-13 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, [키워드] affected Anosmia anosmia/dysgeusia anti-SARS-CoV-2 IgG antibody anti-spike antibody anti-spike antibody response antibody asymptomatic individual Biomarkers Care Comorbidities comparable correlated COVID-19 COVID-19 incidence COVID-19 symptoms dependent on dysgeusia Epidemic exposure to facility family female Fever Frequency geographical location Health healthcare facility hospital IgG IgG antibodies IgG positivity individual individuals infected individuals interactions Italian Italy lombardy magnitude male plasma positive Prevalence questionnaire SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection serology Seven smoker Smokers smoking subject Symptoms tested the SARS-CoV-2 these symptom these symptoms Variation virus [DOI] 10.1038/s41598-021-91773-4 PMC 바로가기 [Article Type] Clinical Trial
Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020SARS-COV-2 Seroprevalence 및 감염 사망률 비율의 추정 및 결정 요인 잠재 계급 분석 : 2020 년 봄 가장 어려운 독일 카운티에서 인구 기반 Tirschenreuth 연구Article Published on 2021-06-102022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, [키워드] accounted age Analysis analyzed antibodies antibody tests Care case fatality ratio CFR class CLIA computation conducted deaths determinant ELISA estimate Factor fatality IFR implication individual Infection infection fatality ratio infections Latent latent class analysis Measures molecular cause outbreak participant proportion Ratio reflected Registered SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection senior care homes Seroprevalence severe SARS severe SARS-CoV-2 smoker Smokers smoking spring suffered underreported infections while [DOI] 10.3390/v13061118 PMC 바로가기 [Article Type] Article
Changes in Smoking Behavior Since the Declaration of the COVID-19 State of Emergency in Japan: A Cross-sectional Study From the Osaka Health AppOriginal Article Published on 2021-06-052022-10-30 Journal: Journal of Epidemiology [Category] COVID-19, MERS, [키워드] 95% CI 95% confidence interval Behavior calculated change changed changes in cigarette conducted covariates COVID-19 COVID-19 pandemic cross-sectional survey declaring the state of emergency Emergency examined Factor Government infection control introduced Japan Japanese less Measures men multivariable Older age outcomes participant Poisson regression prevalence ratio Result risk factor significantly higher significantly lower smoker smoking state Tobacco variables [DOI] 10.2188/jea.JE20200533 PMC 바로가기 [Article Type] Original Article
Smokers’ cognitive and behavioural reactions during the early phase of the COVID-19 pandemic: Findings from the 2020 ITC Four Country Smoking and Vaping SurveyCovid-19 Pandemic의 초기 단계에서 흡연자의인지 및 행동 반응 : 2020 ITC Four Country Smoking and Vaping Survey의 연구 결과Clinical Trial Published on 2021-06-042022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] Analysis association behavioural belief Canada change changes in cognitive conducted confirmed case confirmed cases country COVID-19 cross-sectional cross-sectional study death early phase England examined Factor females finding Government greater health belief Health Belief Model highest immune Impact Infection ITC less lockdowns lowest majority Model National Nicotine nicotine dependence Other pandemic positive public health reaction reduce reduced reducing Regression Regression analyses reported respiratory Respiratory illness response responses Result risk severity of COVID-19 significantly lower smoker Smokers smoking social distancing Stress survey susceptibility susceptibility to infection thinking thought United State United States Wave [DOI] 10.1371/journal.pone.0252427 PMC 바로가기 [Article Type] Clinical Trial
Perceived Stress During the COVID-19-Related Confinement in CyprusPublic Health Published on 2021-06-022022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] average conducted COVID-19 COVID-19 pandemic cross-sectional Cyprus Data collection demographic characteristics Government group health emergency higher risk information Intervention Linear regression model lockdown male mandatory median medium mental health pandemic participated Perceived Perceived stress perceived stress score physical activity physically Prevalence provided Psychological public mental health quarantine questionnaire smoker smoking Stress was done [DOI] 10.3389/fpubh.2021.673411 PMC 바로가기 [Article Type] Public Health
Chronic E-Cigarette Aerosol Inhalation Alters the Immune State of the Lungs and Increases ACE2 Expression, Raising Concern for Altered Response and Susceptibility to SARS-CoV-2Physiology Published on 2021-05-312022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] ACE2 ACE2 expression acute lung injury acute respiratory syndrome addition aerosol aerosol exposure Aerosols Alter alteration Altered angiotensin-converting enzyme 2 BAL C57BL/6 CD1 CD177 CD4 CD4 T cells cell activation change changes in chronic component concern Conventional coronavirus coronavirus disease COVID-19 Defense demonstrated E-cigarette Epidemic form Gene Expression Gene expression analysis GSE hierarchical clustering higher risk Host host cells host response host susceptibility IgA immune Immunoglobulin immunomodulation impairment increase infect Infection Inflammation Inflammatory inflammatory disorder inflammatory pathways inhalation involved Lipidomics lung lung disorders Lung injury Lungs mice moderate monocyte neutrophil neutrophil activation Neutrophils occurred pathogen profile receptor reduced reductions in response RNAseq SARS-CoV-2 SARS-COV-2 infection smoker smoking state suggested susceptibility upregulation vaping [DOI] 10.3389/fphys.2021.649604 PMC 바로가기 [Article Type] Physiology