Could changes in the airborne pollutant particulate matter acting as a viral vector have exerted selective pressure to cause COVID-19 evolution?바이러스 매개체로 작용하는 공기 중 오염 물질 입자상 물질의 변화가 코로나19 진화를 유발하는 선택적 압력을 가했을 수 있습니까?Article Published on 2021-01-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 변종, [키워드] acting addressed adherent affected Air pollution appearance Cardiovascular health Cell changes in China Chinese Clade D Clade G contributed corollary country COVID-19 COVID-19 infection deleterious effect deleterious effects elevated except for form hydrophobic Hypothesis Iceland Immunity implicated incidence index case initial lockdown male matter Mortality mutant Mutation National natural selection outbreak pandemic Particulate Particulate matter Particulate matter (PM) peptide peptides Pollution reported Reproduction number Research respiratory selective shown Smokers smoking Spike protein Spread steadily decreased suggested the spike protein Transmission transmission rate variant vector Viral viral spike protein Viral vector virus Wuhan [DOI] 10.1016/j.mehy.2020.110401 PMC 바로가기 [Article Type] Article
Incidence, Clinical Characteristics, and Evolution of SARS-CoV-2 Infection in Patients With Inflammatory Bowel Disease: A Single-Center Study in Madrid, SpainObservational Study Published on 2021-01-012022-10-05 Journal: Inflammatory bowel diseases [Category] 임상, [키워드] 95% CI 95% confidence interval Analysis biologic clinical Clinical course Comorbidities COVID-19 Crohn disease cross-sectional diagnosed diarrhea died disease Dyspnea female greater IBD identify immunomodulator Immunosuppression incidence Infection Inflammatory bowel disease medical record Mild moderate MOST myalgia Odds ratio one patient Patient patient age patients reported SARS-CoV-2 SARS-COV-2 infection Severe infection severity severity of COVID-19 Smokers Spain Symptom the patient therapy treated Treatment World Health Organization [DOI] 10.1093/ibd/izaa221 PMC 바로가기 [Article Type] Observational Study
Behavioral preventive measures and the use of medicines and herbal products among the public in response to Covid-19 in Bangladesh: A cross-sectional study방글라데시에서 코로나19에 대응한 대중의 행동 예방 조치와 의약품 및 한방 제품 사용: 단면 연구Clinical Trial Published on 2020-12-112022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] adopted age Antibiotics Antihistamines calcium categories conducted cross-sectional cross-sectional survey drug Factor identify information Kruskal-Wallis test management Masks Medicine Medicines MOST multivariable logistic regression pandemic Paracetamol participant preventive measure preventive measures preventive medicines reported significantly smoker Smokers smoking Symptoms was performed was used washing hand washing hands wearing mask were used Zinc [DOI] 10.1371/journal.pone.0243706 PMC 바로가기 [Article Type] Clinical Trial
Prevalence of Depression, Anxiety, and Stress among the General Population in Saudi Arabia during Covid-19 PandemicArticle Published on 2020-12-092022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] Anxiety approach Arabic Care collected Contact coronavirus Coronavirus disease 2019 COVID-19 cross-sectional DASS-21 Depression depressive females General population groups Health Intervention knowledge Mental mental health moderate pandemic participant Population positive Prevalence problems promote Psychological questionnaire reported Saudi Arabia significantly higher Smokers Stress stress levels Stress Scale was used with COVID-19 [DOI] 10.3390/ijerph17249183 PMC 바로가기 [Article Type] Article
Association of Cigarette Smoking, COPD, and Lung Cancer With Expression of SARS-CoV-2 Entry Genes in Human Airway Epithelial CellsMedicine Published on 2020-12-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% confidence interval ACE2 ACE2 (Angiotensin Converting Enzyme-2) affecting Analysis calculated cathepsin L cathpesin L Cell changes in chronic obstructive cigarette CIs contribute COPD COVID-19 decreased expression dependent on effect size effective eligible epithelial cell examined expression expression of SARS-CoV-2 expression profile Genes GEO database GEO dataset healthy control Human human airway epithelial human airway epithelial cells identify increased expression lung cancer mean difference membrane fusion Meta-analysis Patient performed potential risk primary human airway pulmonary disease reduce RStudio SARS-CoV-2 SARS-CoV-2 entry smoker Smokers smoking smoking status TMPRSS2 transcriptomic data transmembrane serine protease 2 was performed [DOI] 10.3389/fmed.2020.619453 PMC 바로가기 [Article Type] Medicine
Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: A comparison of patients with and without SARS-CoV-2 infection코로나19 의심환자 1054명 내원한 성인 1054명의 임상적 특징, 증상 및 결과: SARS-CoV-2 감염 여부 비교Article Published on 2020-12-012022-09-11 Journal: The Journal of Infection [Category] MERS, SARS, 진단, 치료기술, [키워드] 95%CI Anosmia Atypical Bacteria Characteristics characteristics of patient clinical Clinical characteristics Cohort Comorbidities Comparator group COPD COVID-19 COVID-19 patient COVID-19 patients Ethnicity First wave healthcare healthcare worker Healthcare workers hospital hospitalised invasive ventilation Laboratory lack molecular MOST negative patients non-randomised trial outcome outcomes pandemic Patient patient data point-of-care positive presenting reported respiratory respiratory virus respiratory viruses RT-PCR SARS-CoV-2 SARS-COV-2 infection smoker Smokers Symptom Symptoms tested These data viruses was obtained white with COVID-19 [DOI] 10.1016/j.jinf.2020.09.033 PMC 바로가기 [Article Type] Article
Right ventricular-arterial uncoupling independently predicts survival in COVID-19 ARDSResearch Published on 2020-11-302022-11-01 Journal: Critical Care [Category] COVID-19, SARS, [키워드] 95%CI age Analysis ARDS circulation clinically consecutive patient Corona coupling COVID-19 cutoff value deaths echocardiography enrolled evaluated FIO heart failure independent predictor interleukin-6 invasive invasively ventilated patients less majority Mortality Non-survivors noninvasive NT-proBNP oxygen PaO Patient predict Prevalence Prognosis prognostic pulmonary artery pressure respiratory Respiratory failure Result right Right ventricular-arterial uncoupling Smokers survival survivor TAPSE tricuspid ventilatory support ventricular was increased [DOI] 10.1186/s13054-020-03385-5 PMC 바로가기 [Article Type] Research
Association of the COVID‐19 lockdown with smoking, drinking and attempts to quit in England: an analysis of 2019–20 dataResearch Report Published on 2020-11-262022-10-28 Journal: Addiction (Abingdon, England) [Category] COVID-19, SARS, [키워드] adjusted odds ratio age alcohol alcohol dependence alcohol reduction Analysis behavioural changes in COVID‐19 COVID‐19 dependent variable Drinking England finding increase in increases in independent lockdown measurement Odds ratio participant Prevalence quit attempts reduce reduction SARS‐CoV‐2 Sex smoker Smokers smoking smoking cessation Support the timing [DOI] 10.1111/add.15295 PMC 바로가기 [Article Type] Research Report
Risk for COVID-19 infection in patients with tobacco smoke-associated cancers of the upper and lower airwayReview Article Published on 2020-11-202022-10-31 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, MERS, SARS, [키워드] ACE2 Activation advanced age airway Cancer cerebrovascular diseases characterized chronic inflammation chronic obstructive clinical Clinical course Clinical outcome Comorbidity condition COPD COVID-19 COVID-19 infection COVID-19 patient cytokine cytokine release epithelial Factor Gender Head neck cancer iatrogenic IL-6 immune Immunity impairment increased risk Infection Inflammation inflammatory cell Interaction interleukin-6 key factor lower airway lung cancer male morbidity and mortality Multi-organ damage nasal occur overexpressed pathophysiological Patient Patients with cancer receptors respiratory cell Respiratory disease respiratory infectious disease Result review risk Risk factors SARS-CoV-2 replication smoker Smokers syndrome the cytokine storm TMPRSS2 tobacco smoke triggering viral infection [DOI] 10.1007/s00405-020-06456-z PMC 바로가기 [Article Type] Review Article
COVID-19 in Patients with Hematologic Malignancies: A Single-Center ExperienceConference abstract Published on 2020-11-042022-10-05 Journal: Blood [Category] 유전자 메커니즘, [키워드] Absolute lymphocyte count active cancer acute respiratory syndrome age ALC Allogeneic autologous B-cell lymphoma board Cancer therapy cardiac disease Care Cell center Cohort cohort of patient collected Comorbidities Complication conditions conducted coronavirus cough COVID-19 COVID-19 diagnosis COVID-19 in patient COVID-19 infection database defined demographic characteristics described Diagnosis diagnosis of COVID-19 died download electronic medical records expected experience Fever for inclusion funding health system Hematologic malignancy higher risk HM patient Hospital admission ICU immune dysfunction impacted include Infection Innate intubation Jazz Kiowa laboratory data lymphopenia majority median mortality rate Multiple myeloma Nasopharyngeal swab network Older age outcome pandemic Patient patients patients with HM positive result presenting symptom presenting symptoms Prevalence promote rates of infection real-time RT-PCR required Retrospective study risk factor robust SARS-CoV-2 SCT Seattle severe COVID-19 Shortness of breath shown Smokers social distancing specimen subsequent supportive care symptomatic table therapy treated Treatment Two patient underlying disease with COVID-19 [DOI] 10.1182/blood-2020-140719 [Article Type] Conference abstract