COVID-19 autopsy cases: detection of virus in endocrine tissues코로나19 부검 사례: 내분비 조직에서 바이러스 검출Article Published on 2022-01-012022-09-11 Journal: Journal of Endocrinological Investigation [Category] MERS, SARS, 진단, 치료기술, [키워드] adipose Adipose tissue Analysis Autopsy Blood clinically COVID-19 died Effect Endocrine endocrine organ endocrine organs Evidence evidence of Faeces function investigated lung mild cases nine organ Patient phenomenon SARS-CoV-2 SARS-CoV-2 genome Semen severe cases specimen specimens Testis Thyroid tissue tissue sample tissues Urine variety Viral viral genome virus virus spread [DOI] 10.1007/s40618-021-01628-y PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 and Respiratory Virus Sentinel Surveillance, California, USA, May 10, 2020–June 12, 2021중증 급성 호흡기 증후군 코로나바이러스 2 및 호흡기 바이러스 센티넬 감시, 미국 캘리포니아, 2020년 5월 10일–2021년 6월 12일Review Published on 2022-01-012022-09-10 Journal: Emerging Infectious Diseases [Category] SARS, 치료기술, [키워드] activity acute respiratory syndrome age California Co-infection coronavirus coronavirus 2 coronavirus disease Coronaviruses COVID-19 disease enterovirus Health health departments increasingly Latino Local male participants obesity pathogen Pathogens Poisson regression positive respiratory respiratory infections respiratory pathogen Respiratory pathogens respiratory virus respiratory viruses rhinovirus SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 positivity sentinel sentinel surveillance severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen specimens state Surveillance System tested United States USA viruses zoonoses [DOI] 10.3201/eid2801.211682 PMC 바로가기 [Article Type] Review
Patterns of SARS-CoV-2 Testing Preferences in a National Cohort in the United States: Latent Class Analysis of a Discrete Choice Experiment미국 국가 코호트의 SARS-CoV-2 검사 선호도 패턴: 이산 선택 실험의 잠재 클래스 분석Original Paper Published on 2021-12-302022-09-10 Journal: JMIR Public Health and Surveillance [Category] SARS, 변종, [키워드] addition age antibody Antibody test antibody tests Chain Reaction changed choice class Cohort Community community transmission conducted COVID COVID-19 COVID-19 diagnosis COVID-19 pandemic demographic characteristics diagnostic diagnostic testing Discrete discrete choice discrete choice experiment disease distribution dual effort elicited employment estimate experiment faster Features heterogeneity Households identify Inadequate invasive Latent latent class latent class analysis less logit nasal swab National objective offered pandemic participant Participants pattern polymerase chain polymerase chain reaction predict predicted preference preferences public health Result Saliva SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 testing Simulation specimen specimen collection specimens swab specimen test type Testing the United State threat Threats Transmission trend United States uptake utility vaccination Vaccinations Vaccine vaccine availability Vaccines Variability variants Viral widespread would increase [DOI] 10.2196/32846 PMC 바로가기 [Article Type] Original Paper
Potential quality pitfalls of digitalized whole slide image of breast pathology in routine practiceArticle Published on 2021-12-272022-10-04 Journal: Modern pathology : an official journal of the Unit [Category] 바이오마커, [키워드] assessment balancing Breast cancer Cancer clinical impact correlation Diagnosis diagnostic examined fat Final Frequency glass slides Histopathology implementation Laboratory linear measure missing pathology Potential Quality control ranged reduced risk scanning specimens tissue tissue area were assessed [DOI] 10.1038/s41379-021-01000-8 PMC 바로가기 [Article Type] Article
Postmortem Biopsies of the Lung, Heart, Liver, and Spleen of COVID-19 PatientsRadiology Published on 2021-12-272022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acquisition alteration autopsy studies biopsies biopsy Case series Characteristics Chest computed tomography collected Complete coronavirus disease correlated COVID-19 died Diffuse alveolar damage evaluate examined feasible FIVE Ground-glass opacities heart heart tissue histopathologic histopathological infiltration liver lung lung biopsy Lungs material Microscope mononuclear cell Necrosis neutrophil infiltration nonspecific objective Patient patients performed Postmortem Result SARS-CoV-2 specimens spleen spleen tissue Splenic steatosis the patient tissue Treatment underlying disease were stained [DOI] 10.7759/cureus.20734 PMC 바로가기 [Article Type] Radiology
Infection With the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta Variant Is Associated With Higher Recovery of Infectious Virus Compared to the Alpha Variant in Both Unvaccinated and Vaccinated Individuals중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 델타 변이형 감염은 백신 접종을 받지 않은 사람과 백신을 맞은 사람 모두에서 알파 변이형에 비해 감염성 바이러스의 더 높은 회복률과 관련이 있습니다Major Article Published on 2021-12-182022-09-10 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료제, [키워드] (alpha acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Alpha variant anti-SARS-CoV-2 antibody Antiviral B.1.1.7 B.1.617.2 breakthrough infections Capital Capital Region Cell culture circulating clinical chart Cohort Comorbidities coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 cycle threshold Delta delta variant disease severity greater transmissibility groups IgG IgG levels Immunoglobulin Immunoglobulin G increase in Increases increases in individual Infection infections Infectious virus Lineage Local nasal predominant Region respiratory Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 lineage severe acute respiratory syndrome Coronavirus significant increase significantly higher specimens symptomatic the median vaccinated individual vaccinated individuals vaccination variant variants Viral Viral RNA virus VoC Whole genome sequencing [DOI] 10.1093/cid/ciab986 PMC 바로가기 [Article Type] Major Article
Clinical and Laboratory Findings in Patients With Potential Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection, May-July 2020중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 재감염 가능성이 있는 환자의 임상 및 실험실 결과, 2020년 5월-7월Article Published on 2021-12-162022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 antibody Asymptomatic CDC center clinical Clinical course Clinical finding Comorbidities conducted Control coronavirus coronavirus 2 coronavirus disease COVID-19 COVID-19 symptom demographics diagnose diagnoses explained Guidance Infection initial initial symptom interquartile investigated Laboratory laboratory characteristics laboratory finding median medical record network Patient PCR polymerase chain Potential prevention quarantine Reinfection remained reported respiratory reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 positive RT-PCR screened Sequencing specimen specimens Support Symptom Testing the United State viral culture whole genome [DOI] 10.1093/cid/ciab148 PMC 바로가기 [Article Type] Article
Simplified Point-of-Care Full SARS-CoV-2 Genome Sequencing Using Nanopore TechnologyProtocol Published on 2021-12-162022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] (+)RNA genome sequencing Amplicon applied bioinformatics Combination conducted Coverage COVID-19 surveillance criteria Ct value decrease described experiment genome coverage help less local outbreak overlapping Oxford parameter PCR primer set protocol qPCR Rapid recognize SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 pandemic SARS-CoV-2 variant SARS-CoV-2-positive specimen Sequencing specimen specimens Standardization Surveillance technology tested threshold time-consuming variant-of-concern (VOC) variant-of-interest (VOI) variants of concern [DOI] 10.3390/microorganisms9122598 PMC 바로가기 [Article Type] Protocol
Association of Complement and MAPK Activation With SARS-CoV-2–Associated Myocardial InflammationSARS-CoV-2–관련 심근 염증과 보체 및 MAPK 활성화의 연관성Research Published on 2021-12-152022-09-10 Journal: JAMA Cardiology [Category] MERS, SARS, 유전자 메커니즘, [키워드] abundance age Analysis assessment biopsies C1q capture capture sequencing cardiac Cardiomyopathy cascade case sery CD163 center Characteristics characterized clade Cohort cohort of patients collected complement Complement cascade component confirmation cysteine Endomyocardial biopsy Ethnicity Exome exploratory exposure Factor finding Future Germany highest histologic Hospitalized immune pathway immune signature Immune-mediated implication Importance individual Infection Inflammatory inflammatory condition inflammatory conditions inhibitor Injury kinases lymphocyte Lymphocyte count lymphocyte counts Macrophage macrophages male MAPK mass mass spectrometry Maximilian measure median age mitogen mitogen-activated protein kinase Munich Myocardial inflammation myocardial injury myocarditis objective participant Participants pathway Pathways Patient patients with SARS-CoV-2 phenotype Point Protein protein kinase protein kinases proteinase Proteins proteomic Proteomic analysis reduce Referral Relevance Result RNA SARS-COV-2 infection Sequencing Serine setting signaling cascade similarities specimen specimens subunit the median threonine tissue transcript transcriptomic transcriptomic analysis Treatment strategies treatment strategy Tübingen university upregulated upregulation Viral viral myocarditis were measured [DOI] 10.1001/jamacardio.2021.5133 PMC 바로가기 [Article Type] Research
A Study of Analytical and Clinical Sensitivity of Aptima SARS-CoV-2 Assay (Hologic) and Proposals of Complementary Tests for SARS-CoV-2 Detection in Low Viral Load SpecimensAptima SARS-CoV-2 Assay(Hologic)의 분석 및 임상 민감도에 관한 연구 및 낮은 바이러스 부하 표본에서 SARS-CoV-2 검출을 위한 보완 테스트 제안Article Published on 2021-12-142022-09-11 Journal: Current microbiology [Category] SARS, 치료기술, [키워드] Aptima SARS-CoV-2 assay automated calculated clinical detect detection determined by Diagnosis diagnostic diagnostic testing dilution sery evaluated IMPROVE Laboratory limit of detection limitations load positive relative light unit relative light units replicate reported resource RLU SARS-CoV-2 specimen specimens Test tested Transmission true negative viral loads was determined [DOI] 10.1007/s00284-021-02730-3 PMC 바로가기 [Article Type] Article